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Pharmaceutical composition for relieving muscular soreness and preparation method thereof

A kind of technology for muscle soreness and composition, which is applied in the field of medicine, can solve the problems of skin itching, side effects, slow curative effect, etc., and achieve the effect of reducing discomfort and pain

Active Publication Date: 2013-06-12
福州中科伟创生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ibuprofen cream mainly uses the non-steroidal anti-inflammatory drug ibuprofen. Its mechanism of action is to inhibit the synthesis of prostaglandins, thereby exerting an analgesic and anti-inflammatory effect. Although the curative effect is good, it has certain side effects and is not suitable for long-term use by patients.
In addition, traditional Chinese medicine musk ointment or plaster is also used to relax meridians and activate collaterals, relieve muscle pain, but the specificity is not strong, the curative effect is slow, and for some allergic patients, it may cause skin itching, redness, purple spots and other allergies Phenomenon

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Step 1) Weigh the following weights of oil phase component raw materials and put them into the oil phase container to obtain oil phase mixture A: 15 kg of wintergreen oil, 5 kg of menthol, 3 kg of camphor, 3 kg of PPG-5 ceteth- 20. 0.5 kg Phenoxyethanol, 0.5 kg Sodium Polyacrylate (and) Caprylic / Capric Triglycerides (and) Mineral Oil (and) Tris(PPG-3 Myristyl Ether) Citrate (and) Sorbitan Acid Laurate (and) Trideceth-6.

[0032] Weigh the following weights of the water phase component raw materials and throw them into the water phase container to obtain the water phase mixture B: 2 kg of PEG-7 glycerin cocoate, 0.3 kg of carbomer, 72 kg of purified water, 1.0 kg of 10% triethanolamine .

[0033] Wherein the oil phase component is 27 kilograms, and the water phase component is 74.3 kilograms;

[0034] Step 2) Stir and mix the oil phase mixture A evenly;

[0035] Heat the water phase mixture B to 60-65°C, and stir while heating. When the mixture B reaches the above tem...

Embodiment 2

[0038] Step 1) Weigh the following weights of oil phase component raw materials and put them into the oil phase container to obtain oil phase mixture A: 10 kg of wintergreen oil, 3 kg of menthol, 3 kg of camphor, 1 kg of PPG-5 ceteth- 20. 0.5 kg Phenoxyethanol, 0.5 kg Sodium Polyacrylate (and) Caprylic / Capric Triglycerides (and) Mineral Oil (and) Tris(PPG-3 Myristyl Ether) Citrate (and) Sorbitan Acid Laurate (and) Trideceth-6;

[0039] Weigh the following weights of the water phase component raw materials and throw them into the water phase container to obtain the water phase mixture B: 1 kg of PEG-7 glycerol cocoate, 72 kg of purified water, 1.0 kg of 10% triethanolamine;

[0040] Wherein the oil phase component is 18 kilograms, and the water phase component is 73 kilograms;

[0041]Step 2) Stir and mix the oil phase mixture A evenly;

[0042] Heat the water phase mixture B to 60-65°C, and stir while heating. When the mixture B reaches the above temperature, keep stirring f...

Embodiment 3

[0045] Step 1) Weigh the following weights of oil phase component raw materials and put them into the oil phase container to obtain oil phase mixture A: 20 kg of wintergreen oil, 8 kg of menthol, 5 kg of camphor, 5 kg of PPG-5 ceteth- 20. 0.5 kg Phenoxyethanol, 1 kg Sodium Polyacrylate (and) Caprylic / Capric Triglycerides (and) Mineral Oil (and) Tris(PPG-3 Myristyl Ether) Citrate (and) Sorbitan Acid Laurate (and) Trideceth-6;

[0046] Weigh the following water phase component raw materials and put them into the water phase container to obtain the water phase mixture B: 5 kg PEG-7 glycerol cocoate, 0.5 kg carbomer, 75 kg purified water, 1.0 kg 10% triethanolamine ;

[0047] Wherein the oil phase component is 39.5 kilograms, and the water phase component is 80.5 kilograms;

[0048] Step 2) Stir and mix the oil phase mixture A evenly;

[0049] Heat the water phase mixture B to 60-65°C, and stir while heating. When the mixture B reaches the above temperature, keep stirring for 3...

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Abstract

The invention relates to the field of medicine, and in particular relates to a pharmaceutical composition for relieving muscular soreness and a preparation method thereof. The invention aims at providing the pharmaceutical composition which avoids the side effects of Western medicines, overcomes the slow curative effects of traditional Chinese medicines, and is used for relieving muscular soreness, and the preparation method thereof. The pharmaceutical composition for relieving muscular soreness is prepared by mixing the following raw materials in parts by weight: 10-20 parts of wintergreen oil, 3-8 parts of menthol, 1-5 parts of camphor, 1-5 parts of PPG-5 cetyl alcohol polyether-20, 0-0.5 part of phenoxyethanol, and the like. The pharmaceutical composition provided by the invention combines three spices with the analgesic effect, namely, the natural wintergreen oil, the menthol and the camphor, thereby having the superposition accumulative effects in relieving muscular soreness.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for relieving muscle soreness and a preparation method thereof. Background technique [0002] Muscle pain is usually pain caused by rheumatism, bone hyperplasia, bruises and other reasons. Common symptoms occur in muscles, meridians, ligaments and subcutaneous tissue. The occurrence of the disease is caused by fatigue and cold, or due to various violent and unexpected activities, which brings pain to the patient. Seriously affect people's daily work and quality of life. [0003] At present, the cream used to relieve muscle pain mainly includes the Fenbid 5% ibuprofen cream of China American SmithKline. Ibuprofen cream mainly uses the non-steroidal anti-inflammatory drug ibuprofen. Its mechanism of action is to inhibit the synthesis of prostaglandins, thereby exerting an analgesic and anti-inflammatory effect. Although the curative effect is good, i...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61K36/534A61K36/185A61K9/06A61K47/44A61K47/34A61P29/00A61K31/045A61K31/125
Inventor 吴燕斌肖永堂
Owner 福州中科伟创生物科技有限公司
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