Pharmaceutical composition of diclofenac sodium for injection and preparation method thereof

A technology of diclofenac sodium and its composition, which is applied in the field of medicine, can solve the problems of poor long-term stability of diclofenac sodium preparations, high toxicity and side effects, and easy crystallization and degradation, etc., so as to improve the analgesic effect, reduce the damage to the human body, and reduce the dosage Effect
CN107126418BActive Publication Date: 2020-05-29JIANGSU SIMIAO MEDICAL TECH CO LTD
7 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGSU SIMIAO MEDICAL TECH CO LTD
Publication Date
2020-05-29

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Provided in the present invention is a pharmaceutical composition of diclofenac sodium for injection, used for the treatment of mild, moderate, and severe pain; a solution prepared from a formulation comprising the following components or preferably composed of the following components is prepared by freeze drying: diclofenac sodium, a water-soluble cyclodextrin derivative, a stabiliser, and water for injection, the stabiliser increasing the placement stability of the composition.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition of diclofenac sodium for injection and a preparation method of the preparation. Background technique

[0002] Diclofenac Sodium (Diclofenac Sodium) belongs to phenylacetic acid derivatives, is the third generation of powerful non-steroidal anti-inflammatory analgesics, also known as Diclofenac, Futaline, Amirel, white crystalline powder, odorless, It is easily soluble in acetone, soluble in methanol and ethanol, slightly soluble in water, has hygroscopicity, and its molecular formula is C 14 h 10 Cl 2 NNaO 2 , with a molecular weight of 318. The structural formula of diclofenac sodium is as follows:

[0003]

[0004] The main mechanism of action of diclofenac sodium is to inhibit the activity of cyclooxygenase, thereby blocking the conversion of arachidonic acid into prostaglandins. At the same time, it can also promote the combi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More