Method for reconstructing dynamic fluorescence molecular tomography
A technology of fluorescent molecular tomography and fluorescent molecular imaging, which is applied in the field of reconstruction of fluorescent molecular tomographic images, can solve the problems of exceeding the computing power, exceeding the computing power of ordinary computers, occupying space-time weight matrix, etc., to reduce the calculation scale and make up for Time dependency considerations, effects of high data compression
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[0018] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.
[0019] For FMT imaging, based on the first-order Born approximation, the fluorescence projection image acquired at the detection point r can be expressed by the following formula:
[0020] Φ m (r)=∫ r′∈V G(r,r')n(r')Φ x (r')dr' (1)
[0021] In the formula, V is the reconstruction area; Φ x is the light field distribution function, which describes the photon density corresponding to the excitation light wavelength, Φ m is the photon density of the emission (fluorescence) wavelength; n(r′) is the fluorescence yield to be reconstructed at the point r′ in the reconstruction area V, usually n(r′) is proportional to the concentration of the fluorescent probe; Green’s function G( r, r') describe the propagation of photons in the imaging object in the fluorescence band.
[0022] For dynamic FMT, after the reconstruction area V is discretized into a smal...
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