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Chinese medicine effective part composition for treating breast hyperplasia and preparation method of Chinese medicine effective part composition

A technology for effective parts and mammary gland hyperplasia, which is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve the problem of lack of effective therapy for this disease, achieve rapid treatment of mammary gland hyperplasia, and the preparation method is simple and easy to operate. , maintain the effect of active ingredients

Inactive Publication Date: 2013-08-14
广州市云桥生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, modern western medicine lacks an effective treatment for this disease, and an effective treatment drug is urgently needed.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 28g of Baibaibu, 25g of Huashan ginseng, 22g of red cardamom, 15g of grass fruit and 10g of gallinaceous gold, grind them into coarse powder, add 8 times the amount of water, decoct 3 times, and decoct for 2 hours each time; filter the decoction Combine the filtrates, concentrate under reduced pressure to a paste with a relative concentration of 1.2, add ethanol to make the alcohol content 62%, let it stand overnight, reclaim the ethanol, and obtain 1000ml of the concentrated solution, take the simple syrup, add the above concentrated solution, and use citrate Adjust the pH to 4.7 with citric acid, add distilled water to 5000ml, stir evenly, filter and pack into 15ml glass bottles, and pack to obtain oral liquid.

[0018] This product is a yellow clear liquid, which will not produce turbidity within half a year, with a pH of about 4.7 and a total solid of about 7%.

Embodiment 2

[0020] 500 cases of patients were observed clinically, and all patients had obvious clinical symptoms of mammary gland hyperplasia and were diagnosed by clinicians.

[0021] The patient took the oral liquid prepared in Example 1 orally, once a day in the morning and evening, each 15ml.

[0022] After 30 days, the statistical results of patients using the oral liquid obtained in Example 1 are shown in Table 1.

[0023] Efficacy standard: Marked effect includes three grades. The first level is breast pain and lump disappear completely; the second level is premenstrual, angry and tired, the degree of breast pain is significantly reduced compared with before treatment, the size of the lump is reduced by more than half, and there is slight tenderness; the third level is premenstrual, angry and tired After the operation, the pain in the breast was relieved, the texture of the lump became softer, and the volume shrunk by less than half. Ineffective means that after treatment, the s...

Embodiment 3

[0029] The oral liquid prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half male, and the administration was continued for 90 days.

[0030] After pre-testing, the toxicity of the lotion prepared in Example 1 was very low, and the LD50 could not be measured, so the maximum daily dosage was determined for mice. The maximum dosage is 100ml / d. After 90 days, there is no case of poisoning death, and all of them are alive and healthy. This proves that the oral liquid made from the composition of the present invention will not cause toxic and side effects to the human body.

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PUM

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Abstract

The invention discloses a Chinese medicine effective part composition for treating breast hyperplasia. The Chinese medicine effective part composition is prepared from the following raw materials in parts by weight: tuber siemona root, physochlaina macrophylla, fructus galangae, tsaoko amomum fruit and endothelium corneum gigeriae galli. The Chinese medicine effective part can be prepared into medicines for treating the breast hyperplasia, has the effects of soothing the liver, regulating vital energy, dispelling melancholy, dredging collaterals, softening hard mass, reliving mass, promoting blood circulation and removing stasis, can be used for remarkably treating the breast hyperplasia and has the effects of no toxic or side effects and high safety.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition of effective fractions of traditional Chinese medicines for treating mammary gland hyperplasia and a preparation method thereof. Background technique [0002] Mammary hyperplasia refers to single or multiple benign hyperplasia of mammary ducts, mammary lobules, acinar epithelium, and fibrous tissue. The main clinical features are periodically aggravated breast tenderness and multiple breast masses. This disease is relatively common, and its incidence rate is reported to be about 10% in China, and it mostly occurs in women aged 30 to 50, and it also occurs in men. The cause of this disease has not been clarified so far, but it is mainly believed to be related to the endocrine dysfunction of the human body, especially the ovarian dysfunction of women. [0003] At present, modern western medicine lacks an effective treatment for this disease, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P15/14A61K35/37A61K35/57
Inventor 张群
Owner 广州市云桥生物科技有限公司