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Device for measuring overall mechanical characteristics of eyeball of living animal and method of device

A technology of mechanical properties and animals, which is applied in the direction of eye testing equipment, applications, medical science, etc., can solve problems such as eyeball structure damage, eyeball self-structural damage, eyeball biomechanical properties and actual mechanical property errors, etc., to achieve simple structure, Easy assembly and disassembly, the effect of improving the detection ability

Inactive Publication Date: 2013-09-11
TAIYUAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the structure of the eyeball itself will be destroyed during the in vitro test, the factors affecting the interaction between the living body and the eyeball and the structure of the eyeball itself have a greater impact on the biomechanical properties of the eyeball.
Therefore, there is a large error between the biomechanical properties of the eyeball obtained by this test method and the actual mechanical properties.
In addition, the same eyeball can only be used for one test because the structure of the eyeball will be damaged during the in vitro test. As a result, this in vitro test method cannot verify certain lesions, drug effects, or LASK surgery on the same living body. Effects of Cutting Depth on Biomechanical Properties of Eyeball

Method used

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  • Device for measuring overall mechanical characteristics of eyeball of living animal and method of device
  • Device for measuring overall mechanical characteristics of eyeball of living animal and method of device
  • Device for measuring overall mechanical characteristics of eyeball of living animal and method of device

Examples

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Effect test

Embodiment 1

[0028] A device for measuring the overall biomechanical characteristics of the eyeball of a living animal, the device includes a measuring machine lifting bracket, a vertical measuring bracket, a video camera, a horizontal fixed platform, a glass tube, a flexible tube, an infusion syringe, a shut-off valve and a horizontal operating platform; its compositional relationship as follows:

[0029] Select a stainless steel material that meets medical requirements to make a level measuring machine base, install a measuring machine lifting bracket 1 vertically on the level measuring machine base, and connect and fix the measuring machine lifting bracket 1 through the camera bracket connector 4 There is a camera support 7 capable of lifting up and down and a mobile camera 8 arranged on the support; the mobile camera 8 is corresponding to the vertical glass tube 11 arranged on the lifting support 1 of the measuring machine, and is used to record the temperature in the glass tube 11. Th...

Embodiment 2

[0036] Implement the above-mentioned a kind of measuring method of the measuring device that is used for measuring the overall mechanical characteristic of living animal eyeball of the present invention, this method is to carry out according to the following steps:

[0037] Step 1. Disinfect the measuring device according to the medical and health requirements, fill the glass tube 11 and its pipeline with physiological saline for cleaning, exhaust the air, and then fill it with physiological saline to the height of the glass tube 11 to the required measurement live eye The liquid height of the measurement of animal ball overall mechanical property is approximately the top of selecting glass tube 11 heights.

[0038] Step 2: Set a fixed marking line 5 on the glass tube 11 as the camera reference line for liquid level changes, then set a crown suspension mark 6 on the surface of the saline in the glass tube 11 to float with the liquid level, and the camera 8 tracks the liquid lev...

specific Embodiment 3

[0047] Taking the New Zealand white rabbit as an example, before the measurement, the environment for the live animal measurement and the living animal measuring instrument are thoroughly disinfected first, and the anesthetized New Zealand white rabbit is fixed on the horizontal operating table 18 where the spatial position can be adjusted. On a flat surface, the eyelid speculum stretches the eyelids. Then the infusion set 17, the flexible pipe 14 and the thin glass tube 13 are filled with physiological saline.

[0048] The specific method is to use negative pressure suction to prevent the generation of air bubbles. Adjust the relative height of the liquid level buoy and the center of the eyeball of the test animal by lifting the universal material test and the lifting arm, so that it can approximately reach the statistical intraocular pressure value of the animal (about 200 mmH 2 O), and at the same time, calibrate the camera extensometer so that it can track the distance ch...

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Abstract

The invention relates to a device for measuring overall mechanical characteristics of an eyeball of a living animal, and a method of the device. The device is characterized in that a movable camera and a glass tube are fixed on a lifting support; the end of the glass tube is communicated with a hose and an infusion syringe; and a stop valve and a horizontal operating platform for injecting to the eyeball of the living animal are arranged on the infusion syringe. The method comprises the steps of communicating internal and external testing devices of the eyeball in a puncture injection manner for the eyeball of the experimental animal according to a communicator principle, and calculating to obtain the overall biomechanical characteristics of the eyeball, such as rigidity and elastic modulus by changing a liquid level of the external testing device. With the adoption of the device and the method, accurate measurement of a biomechanical characteristic carrier of the eyeball of the experimental animal is realized, the detectability of influence of ocular diseases and drugs on the biomechanical characteristics of the eyeball, and theoretical data is provided for selecting LASK (Laser Assisted In-situ Keratomi) operation parameters.

Description

technical field [0001] The invention relates to a device for measuring the mechanical properties of animal eyeballs and a measuring method thereof, in particular to a device for measuring the overall mechanical properties of living animal eyeballs and a measuring method thereof. Background technique [0002] When studying the effects of glaucoma, keratoconus and other ophthalmic diseases on the biomechanical properties of the eyeball, the overall biomechanical properties of the eyeball, such as the overall The determination of stiffness and elastic modulus is the first problem that researchers need to solve. [0003] The existing biomechanical properties of the eyeball are usually tested under in vitro conditions after the animal's eyeball is removed, and then the cornea or sclera is separated to make a non-standard test piece that can be clamped by the experimental equipment. However, because the structure of the eyeball itself will be destroyed during the in vitro test, t...

Claims

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Application Information

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IPC IPC(8): A61B3/10
Inventor 王晓君陈维毅
Owner TAIYUAN UNIV OF TECH
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