Method for purifying mixed organic salts obtained by microbial fermentation production of 1, 3-propanediol

Abstract

the invention provides a method for purifying mixed organic salts obtained by microbial fermentation production of 1, 3-propanediol. When 1, 3-propanediol is produced by microbial fermentation based on glycerine as a raw material, byproducts organic acids can be produced, in order to maintain the fermentation pH value unchanged, alkali is usually added for neutralization, so that the byproducts organic salts which comprise sodium succinate, sodium lactate and sodium acetate (for example, when liquid ammonia is taken as a neutralizing agent, ammonium salts of the mixed organic acids are obtained) can be obtained at the end of fermentation. According to the method, pure succinic acid, sodium sulfate (or ammonium sulfate) and other products can be obtained through a series of methods, such as deionized water dissolution, addition of concentrated sulfuric acid for crystallization, separation and mother liquor evaporation. According to the method, the use of a large number of the byproducts organic salts in the production of polyols through a biological method can be solved, the product succinic acid with high added value can be further obtained, and the economic benefits and the social benefits can be greatly improved.

Description

technical field [0001] The invention relates to a method for purifying mixed organic salts obtained by fermenting microorganisms to produce 1,3-propanediol, and belongs to the field of biochemical synthesis. Background technique [0002] The existing method for producing 1,3-propanediol by microbial fermentation is to use glycerol as a raw material to produce 1,3-propanediol by microbial fermentation, and the strains used include Klebsiella pneumoniae and Klebsiella acidogens Or any of Clostridium butyricum, etc., these bacteria have the ability to convert glycerol into 1,3-propanediol. However, microorganisms will by-produce a large amount of organic acids during the production process. In order to maintain the fermentation environment unchanged, the pH value can only be adjusted by adding alkali to neutralize, so as to maintain the environment in the fermenter to facilitate the growth and production of bacteria. The organic acids produced by microorganisms during the ferm...

AI Technical Summary

Problems solved by technology

Although mixed organic salts can be used as snow-melting agents for airports or highways, a large amount of by-products will accumulate in summer. Moreover, it is uneconomical to consume a large amount of organic salts as snow-melting agents and is a waste of resources. waste of