Special extraction device for main ingredient collagen II of natural cartilage matrix

A technology of cartilage matrix and collagen, which is applied in the direction of animal/human protein, peptide preparation methods, connective tissue peptides, etc., can solve the problems of reduced production and preparation efficiency and increased labor costs, so as to save manpower, reduce production costs, and improve The effect of production efficiency

Active Publication Date: 2015-04-08
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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Problems solved by technology

[0004] However, since tissue engineering scaffold materials generally select materials with the same main components as human normal articular cartilage extracellular matrix as bionic raw materials for the preparation of bionic cartilage extracellular matrix for tissue engineering, multiple steps and long-term processing are required in the preparation process , and the preparation process requires long-term stirring and centrifugation, and it usually takes 20 days to prepare a tissue engineering scaffold material. If manual operations are used, it will lead to increased labor costs and reduced production efficiency. defect

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  • Special extraction device for main ingredient collagen II of natural cartilage matrix
  • Special extraction device for main ingredient collagen II of natural cartilage matrix
  • Special extraction device for main ingredient collagen II of natural cartilage matrix

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Embodiment Construction

[0039] The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0040] Such as figure 1 Shown is a schematic structural diagram of an embodiment of a special device for extracting type II collagen, the main component of the natural cartilage matrix of the present invention. The main component of the natural cartilage matrix in this embodiment-the special device for extracting type II collagen, includes a thermostat 1, a centrifugal device arranged in the thermostat 1, and a control system for controlling the temperature in the thermostat 1 and the action of the centrifugal device. The device includes a centrifuge, a container device installed on the centrifuge, a liquid addition system for adding reagents to the container device, a filter drainage system for discharging waste liquid in the container device, and a stirring system for stirring the reagents.

[0041] The centrifuge includes a base 2 and a t...

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Abstract

The invention discloses a special extraction device for main ingredient collagen II of natural cartilage matrix. The special extraction device comprises an incubator, a centrifugal device arranged in the incubator, and a control system used for controlling the temperature in the incubator and the action of the centrifugal device, wherein the centrifugal device comprises a centrifugal machine, a container device installed on the centrifugal machine, a liquid adding system used for adding a reagent into the container device, a filtering and liquid discharging system used for discharging waste liquid in the container device, and a stirring system used for stirring the reagent. The special extraction device for main ingredient collagen II of natural cartilage matrix disclosed by the invention can be used for automatically completing the extraction of the main ingredient collagen II of the natural cartilage matrix, effectively saving the manpower, reducing the production cost and improving the production efficiency.

Description

technical field [0001] The invention relates to a professional production device for type II collagen, in particular to a special device for extracting type II collagen, the main component of natural cartilage matrix, and the extracted type II collagen is mainly used for injectable tissue engineering cartilage gel matrix preparation. Background technique [0002] Cartilage defects in joints caused by trauma or bone disease are common clinically, seriously affect the quality of life of patients, and have become one of the main causes of physical disabilities. The incidence rate in the United States is 1.5‰~3‰, and in my country it is about 5 to 6 times that of the United States, and it is increasing year by year. Articular cartilage belongs to hyaline cartilage, lacks neurovascular nutrition, and is difficult to repair itself after injury. There are obvious defects in the existing clinical treatment measures. The conservative treatment and joint debridement can only tempora...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K14/78C07K1/34
Inventor 王富友陈诚龚啸元刘清宇刘俊利杨柳
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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