A digital simulation method of blood regurgitation in mitral regurgitation

A regurgitation, digital simulation technology, applied in the field of cardiovascular system, can solve the problems of mitral valve regurgitation simulation calculation error, simulated mitral valve closure, unable to measure changes in physiological parameters, etc.

Inactive Publication Date: 2016-04-06
XIAMEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If only the cardiac circulatory system is considered, the simulation calculation of mitral regurgitation will produce large errors
[0005] 2) The current mitral regurgitation simulation method cannot quantitatively simulate different degrees of mitral regurgitation, and can only simulate the "existence" or "absence" of mitral regurgitation
[0006] 3) The current mitral regurgitation simulation method only simulates the blood regurgitation, but cannot measure left ventricular pressure, left ventricular volume, left atrial pressure, left atrial volume, pulmonary venous pressure, mitral valve flow, and mitral valve volume Changes in relevant physiological parameters

Method used

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  • A digital simulation method of blood regurgitation in mitral regurgitation
  • A digital simulation method of blood regurgitation in mitral regurgitation
  • A digital simulation method of blood regurgitation in mitral regurgitation

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Embodiment Construction

[0081] The following embodiments will further illustrate the present invention in conjunction with the accompanying drawings.

[0082] The concrete steps of the embodiment of the present invention are as follows:

[0083] step one,

[0084] according to figure 1 A four-chamber lumped parameter cardiovascular dynamic circuit model was established. The meaning of each component in the circuit and the simulated physiological significance of the representation are shown in Table 1.

[0085] Step two,

[0086] According to the circuit model established in step 1, the established dynamic circuit is analyzed by the state variable analysis method, and the corresponding state equations are established for the relevant nodes in the circuit according to the formula in the specification.

[0087] Step 3. Set the corresponding parameters (see Table 4 for details) and solve the state equation, where D M The value of is according to the following formula, which represents the situation ...

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Abstract

The invention relates to cardiovascular systems, in particular to a digital simulation method for blood backflow caused by mitral valve insufficiency. A, a four-cavity lumped parameter angiocarpy dynamic circuit model equivalent to lesser circulation system, a systemic circulation system, a left heart circulation system and a right heart circulation system is established according to the equivalent relation of hemodynamics parameters and circuit parameters; B, according to the circuit model established in the step A, an established dynamic circuit is analyzed through a state variable analysis method, and corresponding state equations are established for related nodes in the circuit; C, according to simulation needs, the corresponding parameters in the step A and the step B are set, the state equations are solved according to the circuit model arranged in the step A and the state equations arranged in the step B, and the time curve graphs of the nodes in the circuit are obtained; D, QM obtained in the step C is calculated, and the blood backflow amount VRM, the mitral valve forward output amount VFM and the mitral valve volume VM under the condition that the mitral valve insufficiency occurs are obtained.

Description

technical field [0001] The invention relates to a cardiovascular system, in particular to a digital simulation method for mitral regurgitation insufficiency blood backflow. Background technique [0002] Mitral valve insufficiency is one of the common pathological phenomena in cardiovascular diseases. It is caused by the failure of the mitral valve to close normally during systole, and blood flows from the left ventricle to the aorta while part of the blood flows back from the left ventricle to the left atrium. . Mitral valve insufficiency can produce blood regurgitation, which can cause dilation of the left ventricle and dysfunction of the left ventricle, and even lead to heart failure and even death in severe cases. The study of blood regurgitation during mitral valve insufficiency, especially the impact of different degrees of insufficiency on blood regurgitation, has important guiding significance for mitral valve clinical repair and valve replacement surgery. [0003] ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F17/50
Inventor 黄晓阳赵晓佳苏茂龙钟琪冯敏
Owner XIAMEN UNIV
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