Homopolysaccharide in ganoderma sinensis submerged fermentation mycelium, as well as preparation method and applications thereof

A technology of submerged liquid fermentation and mycelium, which is applied in the fields of allergic diseases, antineoplastic drugs, drug combinations, etc., can solve the problems of inability to investigate the mechanism of antitumor action, unclear active ingredients, low polysaccharide content, etc., and achieve active ingredients The effect of single clear, excellent dosage, high polysaccharide content
CN103374078AActive Publication Date: 2013-10-30JIANGSU KANION PHARMA CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU KANION PHARMA CO LTD
Publication Date
2013-10-30

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Abstract

The invention discloses a preparation method of homopolysaccharide which exists in ganoderma sinensis submerged fermentation mycelium and has a novel structure, and applications of the homopolysaccharide in the preparation of antineoplastic drugs and immune adjustment drugs. The homopolysaccharide is characterized in that the total polysaccharide content of the homopolysaccharide is more than 95%, the molecular weight of the homopolysaccharide is 10000-30000 Daltons, and preferentially is 21190 Daltons, and the homopolysaccharide has the characteristics of high efficiency, low toxicity and immunity enhancement in the antineoplastic application. The homopolysaccharide in the ganoderma sinensis submerged fermentation mycelium, provided by the invention, is high in polysaccharide content and purity, and is excellent in administration dosage, and the preparation method is suitable for industrial production.
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Description

technical field

[0001] The present invention relates to the homogeneous polysaccharide GS-A-1 of Zizhi liquid submerged fermentation mycelium, its preparation method and its use in the preparation of antitumor drugs and immunomodulators. Background technique

[0002] Tumor is one of the most common and serious diseases that directly threaten human life in today's world, so how to effectively prevent and treat tumor has become a hot spot in the medical field. While prolonging the life of cancer patients, traditional surgery, radiotherapy and chemotherapy will produce side effects such as damage to internal organs and suppression of immune function, which will significantly reduce the quality of life of patients. At present, fungal polysaccharides are often used in the adjuvant therapy of tumors because of their advantages of less toxic side effects, high safety, and good tumor inhibition effect.

[0003] Edible and medicinal fungi have various functions such as anti-tumor an...

Claims

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