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Natural medicine extract and preparation method thereof

A technology of extract and natural medicine, applied in the field of natural medicine extract and its preparation

Inactive Publication Date: 2013-11-20
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural medicine extract and preparation method thereof

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Experimental program
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Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of the concentrated extract of radish seed Baimuxiang decoction

[0037] According to the compatibility ratio of 1-4:1, take radish and white wood, soak in distilled water, heat and decoct, filter, add distilled water to the medicine dregs, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate, super Membrane filtration, drying under reduced pressure, that is.

[0038] (2) Preparation of Raphanusin

[0039] Grind radish seeds, add excess n-hexane to degrease, enzymatically hydrolyze with pH 7.0 phosphate buffer, add dichloromethane to extract 3 times, combine solvents, remove organic solvent under reduced pressure, and dissolve the residue with 10% ethanol solution by volume fraction , extracted three times with n-hexane to remove grease, then extracted the ethanol phase three times with dichloromethane, combined the solvents, and removed the dichloromethane by rota...

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Abstract

The invention relates to a natural medicine extract and a preparation method thereof. The natural medicine extract comprises a radish seed and aquilaria sinensis-decocted concentration extract, sulforaphane, an aquilaria sinensis chloroform extract and an aquilaria sinensis hexane extract according to the ratio of (2-5):(6-9):(2-5):(3-6). The composition has good curative effect on the cancer chemotherapy-induced diarrhea, and can play a synergism role in cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine extract, more specifically relate to a kind of natural medicine extract that is composed of radish seed and white wood perfume decoction concentrated extract, radish, white wood chloroform extract and white wood hexane extract, the said The preparation method of the natural medicine extract and the use of the natural medicine extract in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemother...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P35/00A61P1/12A61K31/26
Inventor 石强
Owner 石强