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System and method for optical coherence tomography

A technology of optical coherence and analysis, which is applied in the field of optical coherence tomography, can solve problems such as ghosting, small depth resolution, and signal-to-noise ratio that cannot always be achieved, and achieve low cost, high resolution and Image quality, effect of noise reduction

Inactive Publication Date: 2013-11-27
T2PHARMA GMBH
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Problems solved by technology

However, only small depth resolutions can usually be achieved with light from such sources
In addition, when using spatially resolved planar sensors at the same time, so-called ghost images can occur due to coherent crosstalk, which can only be avoided by an approximately complete destruction of the spatial correlation, which requires a certain technical effort on the one hand. , and on the other hand is only conditionally achieved despite the technical expense
In the case of superimposing light from multiple different SLDs into one light source, ghost images may additionally be caused due to side lobe maxima in the spectrum
Furthermore, when using SLDs, a sufficient signal-to-noise ratio for high image quality cannot always be achieved due to their relatively low power of at most approximately 20 mW, which also decreases with increasing spectral bandwidth.

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Embodiment Construction

[0044] figure 1 A schematic diagram of a system for optical coherence tomography with an interferometer 10 is shown, the system comprising a beam splitter 11 , an illumination arm 12 , a reference arm 13 , a sample arm 14 , and a detector arm 15 . Furthermore, a radiation wave 21 is provided for generating light, which is filtered by an optical filter 22 and focused by an optical system consisting of lenses 23 and 24 into an input region 25 of an optical waveguide 26 . The radiation source 21 together with the optical filter 22 forms what is also referred to as light source 20 in connection with the invention.

[0045] The light of radiation source 20 coupled into light guide 26 by means of lenses 23 and 24 is coupled into illumination arm 12 of interferometer 10 via optical system 28 in output region 27 of the light guide. From there the light coupled in first reaches a beam splitter 11, through which it is forwarded on the one hand into a reference arm 13 and reflected by a...

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Abstract

The system has interferometer (10) for irradiating a sample (1) with light emitted from light source. A detector (40) is provided for detection of light reflected from sample. The light source has radiation source (21) for producing spatially incoherent light. An optical filter (22) has with a bell-shaped or Gaussian spectral filter characteristic for filtering the signal produced by the radiation source of light. An independent claim is included for method for performing optical coherence tomography.

Description

technical field [0001] The invention relates to a system for optical coherence tomography and a corresponding method according to the preambles of the independent claims. Background technique [0002] Optical coherence tomography (OCT) is a method in which light is scattered inside a sample to make measurements on the sample. With OCT, biological tissue is particularly suitable for diagnostic examination due to its light-scattering properties. Because OCT is sufficient with a relatively small light intensity and the wavelength of the light used is mostly in the near-infrared range (750 nm to 1350 nm), OCT has no radiation burden on biological tissues compared to ionizing X-ray diagnostics. Therefore, OCT is of great significance especially for medicine and is roughly similar to ultrasonic diagnosis, in that instead of sound waves, light is used in OCT. The travel time of the reflected light at different boundary layers in the sample is detected by means of an interferomete...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01B9/02G01N21/47
CPCA61B3/00A61B5/0059G01B9/02001G01B9/02091G01N21/4795A61B5/0066
Inventor R.内博西斯
Owner T2PHARMA GMBH