Check patentability & draft patents in minutes with Patsnap Eureka AI!

A kind of pellet with tartaric acid as main component

A technology of tartaric acid and pellets, which is applied in the field of medicine and food, can solve the problems of no products coming out, and achieve the effects of convenient preparation, low cost and good drug release reproducibility

Active Publication Date: 2015-12-23
杭州高成生物营养技术有限公司
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Yet at present, tartaric acid is made into drug-loaded pill core, and as base pill, still sees bibliographical information at home and abroad, more does not have product to come out

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of pellet with tartaric acid as main component
  • A kind of pellet with tartaric acid as main component

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] According to the component weight ratio of the micropill with tartaric acid as main component, get tartaric acid: 420g (35%), microcrystalline fiber: 300g (25%), starch: 180g (15%), citric acid: 120g (10%) ), sodium bicarbonate: 120g (10%), povidone K30: 60g (5%).

[0013] Dissolve povidone K30 in 95% ethanol, then fully mix tartaric acid, microcrystalline cellulose, starch, citric acid, and sodium bicarbonate, and then place it in a running centrifugal granulator for preparation. Parameters in operation, the range of air intake is standardized air supply: 0.9-1.1(m 3 / h) / kg, the rotational speed of the centrifugal granulation of the spheronizer is 160-180rpm, the rotational speed of the spray gun is 40-50rpm, and the flow rate is controlled at 50-80rpm, so that pellets of 0.2-1.2mm can be prepared.

Embodiment 2

[0015] According to the component weight ratio of the micropill with tartaric acid as main component, get tartaric acid: 600g (50%), microcrystalline fiber: 240g (20%), starch: 120g (10%), citric acid: 120g (10%) ), sodium bicarbonate: 60g (5%), povidone K30: 60g (5%).

[0016] Dissolve povidone K30 in 95% ethanol, then fully mix tartaric acid, microcrystalline cellulose, starch, citric acid, and sodium bicarbonate, and then place it in a running centrifugal granulator for preparation. Parameters in operation, the range of air intake is standardized air supply: 0.9-1.1(m 3 / h) / kg, the rotational speed of the centrifugal granulation of the spheronizer is 160-180rpm, the rotational speed of the spray gun is 40-50rpm, and the flow rate is controlled at 50-80rpm, so that pellets of 0.2-1.2mm can be prepared.

Embodiment 3

[0018] According to the component weight ratio of the micropill with tartaric acid as main component, get tartaric acid: 300g (37.5%), microcrystalline fiber: 150g (18.75%), starch: 150g (18.75%), citric acid: 70g (8.75%) ), sodium bicarbonate: 70g (8.75%), povidone K30: 60g (7.5%).

[0019] Dissolve povidone K30 in 95% ethanol, then fully mix tartaric acid, microcrystalline cellulose, starch, citric acid, and sodium bicarbonate, and then place it in a running centrifugal granulator for preparation. Parameters in operation, the range of air intake is standardized air supply: 0.9-1.1(m 3 / h) / kg, the rotational speed of the centrifugal granulation of the spheronizer is 160-180rpm, the rotational speed of the spray gun is 40-50rpm, and the flow rate is controlled at 50-80rpm, so that pellets of 0.2-1.2mm can be prepared.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pellet with tartaric acid as a main ingredient. The tartaric acid with a content of more than 98% is selected as the main ingredient, microcrystalline cellulose and povidone are added as adhesives, starch is added as a diluent, and foaming agents are further added to obtain the pellet through a centrifugal granulation process. The pellet with the tartaric acid as the main ingredient can be made into various gastric soluble and intestinal soluble pills and has the advantages of good drug release reproducibility, convenience in preparation, low cost, and the like.

Description

technical field [0001] The invention relates to a pellet with tartaric acid as the main component, belonging to the technical field of medicine and food. Background technique [0002] Tartaric acid, namely, 2,3-dihydroxysuccinic acid, is a carboxylic acid that exists in various plants and is also one of the main organic acids in wine. As an antioxidant added to food, it can make food sour. The largest use of tartaric acid is as a beverage additive and as a raw material for pharmaceutical preparations. For some drugs that are stable under acidic conditions, tartaric acid can be combined with these drugs to form a preparation to stabilize the drug and at the same time promote its release to maximize its efficacy. Yet at present, tartaric acid is made into drug-loaded pill core, and as base pill, still sees bibliographical information at home and abroad, more does not have product to come out. Contents of the invention [0003] The object of the present invention is to pro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K47/12A61K47/38A23L1/03A23L2/52A23L29/00
Inventor 冯利萍
Owner 杭州高成生物营养技术有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com