Preparation method of 1,1,1,4,4,4-hexafluoro-2-butyne

Abstract

The invention discloses a preparation method of 1,1,1,4,4,4-hexafluoro-2-butyne. In the present of an organic solvent and under the action of a reaction auxiliary agent, 1,1,1,4,4,4-hexafluoro-2,3-dichloro-2-butene and zinc powder are subjected to carry out a reductive dechlorination reaction so as to obtain 1,1,1,4,4,4-hexafluoro-2-butyne. The preparation method has the advantages of low raw material cost, simple operation, mild reactions, quick reaction speed, high yield, low cost, and high selectivity.

Description

technical field [0001] The invention relates to a preparation method of 1,1,1,4,4,4-hexafluoro-2-butyne. Background technique [0002] 1,1,1,4,4,4-hexafluoro-2-butyne is an important fluorine-containing fine chemical raw material, which can be used to synthesize key intermediates and As a monomer of fluorine-containing polymers, for example, it can be used as a key intermediate for the synthesis of ortho-bistrifluoromethyl benzene ring or heterocycle, cis (Z) hexafluoro-2-butene, etc. The preparation method of hexafluoro-2-butyne in prior art report mainly contains following several kinds: (1) Using trichlorethylene as raw material to prepare hexafluoro-2-butyne by synthesizing perchlorobutadiene: Frank, C. F and Blackham, A. U use benzoyl peroxide to initiate dimerization of trichlorethylene to hexachloro-1-butene (Frank, C. F, Blackham, A. U. J. Am. Chem. Soc . 1950(72), 3283), patent FR836719 reported catalytic hydrogenation while eliminating hydrogen chloride to ...

AI Technical Summary

Problems solved by technology

The main problem of this technology is that the raw material 2-butynedioic acid used is not easy to obtain, and the raw material price of sulfur tetrafluoride is high. This synthetic route is not suitable for industrial production

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