Production equipment for hemodialysis concentrated solution and production method for hemodialysis concentrated solution

A technology of hemodialysis and production equipment, which is applied in the field of medical devices, can solve the problems of shortening the life of dialysis patients, affecting production efficiency, limiting filtration speed, etc., and achieves the effect of simple structure, small mechanical loss, and improved clarity

Active Publication Date: 2013-12-11
吉林省富生医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Hemodialysis concentrate is used for dialysis treatment for patients with acute and chronic renal failure and drug poisoning. Its main function is to eliminate toxic metabolites in the body and correct water, electrolyte, and acid-base disorders. The clinical use is huge; the hemodialysis concentrate contains Harmful indicators - the content of endotoxin determines the quality of hemodialysis concentrate, and the quality of hemodialysis concentrate determines the quality of life of hemodialysis patients; the endotoxin index of domestic hemodialysis concentrate is ≤0.5EU / ml, while The international index is ≤0.25EU / ml. Studies have shown that the chronic poisoning of many hemodialysis patients is caused by endotoxin. Endotoxin can cause a series of interleukin activity processes in the body of the patient, causing damage to the body and shortening the life of the dialysis patient. Enterprises that produce hemodialysis concentrates dissolve the raw materials and then filter them to remove large particles and endotoxins in the products as much as possible. Most of the filter membranes used for filtration are very fine, the filtration speed is limited, and the production efficiency is affected.

Method used

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  • Production equipment for hemodialysis concentrated solution and production method for hemodialysis concentrated solution
  • Production equipment for hemodialysis concentrated solution and production method for hemodialysis concentrated solution
  • Production equipment for hemodialysis concentrated solution and production method for hemodialysis concentrated solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Production volume and raw material volume of liquid A

[0025] Production volume (L)

1000

2000

3000

5000

Sodium chloride (Kg)

210.00

420.00

630.00

1050

Potassium chloride (Kg)

5.22

10.44

15.66

26.10

Calcium chloride (Kg)

9.00

18.00

27.00

45.00

Magnesium chloride (Kg)

3.56

7.12

10.68

17.80

[0026] Step 1: Put the material into the dissolution tank 1, add dialysis water to the amount required by the process to fully dissolve and set the volume to the specified scale, and stir the solution in the dissolution tank evenly;

[0027] Step 2: Start the booster pump 1, inject the solution in the dissolution tank 1 into the adsorber 2, and spray the solution down in the absorber 2 through the nozzle 10, and then pass through the horizontal parallel arrangement in the absorber 2 Two partitions 8 divide the inner chamber of the adsorber 2 into three sections....

Embodiment 2

[0035] Production volume of B liquid and specifications of adsorber and plate-and-frame filter

[0036]

[0037] The production steps are the same as in Example 1; another group of adsorbers 2 is used for the filtration of the solution, and at the same time, the adsorbers 2 used in the previous shift are backwashed and activated. The treatment steps are as follows: first use drinking water to backwash for 10 minutes Drain the drinking water, then fill the activation solution made of 3% hydrogen peroxide and soak for 30 minutes, drain the activation solution, then rinse with drinking water for 10 minutes, drain the drinking water, and wash with dialysis water for 5 minutes; wait Use one shift.

[0038]The adsorber 2 and the separator 8 are made of 316L stainless steel, which has strong corrosion resistance and improves the service life of the equipment.

[0039] By adopting the technical scheme of the present invention, the endotoxin content of the prepared hemodialysis con...

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PUM

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Abstract

The invention discloses production equipment for a hemodialysis concentrated solution. The production equipment comprises a dissolving tank, an adsorber and a filter which are connected in series in sequence, wherein a pipeline for connecting the dissolving tank and the adsorber is provided with a pressurizing pump I; a pipeline for connecting the adsorber and the filter is provided with a pressurizing pump II; an adsorbent is filled into the adsorber. The invention further discloses a production method for the hemodialysis concentrated solution. According to the technical scheme of the invention, the content of endotoxin in the prepared hemodialysis concentrated solution can reach the international standard of being less than or equal to 0.25 EU / ml, the clarity is increased remarkably and can reach the standard of being less than or equal to 0.5 color solution, the quality of the hemodialysis concentrated solution is ensured, chronic intoxication of a hemodialysis patient is delayed, and the living quality is improved.

Description

technical field [0001] The invention belongs to the field of medical devices, and more specifically, the invention relates to a production equipment of a hemodialysis concentrate and a production method of the hemodialysis concentrate. Background technique [0002] Hemodialysis concentrate is used for dialysis treatment for patients with acute and chronic renal failure and drug poisoning. Its main function is to eliminate toxic metabolites in the body and correct water, electrolyte, and acid-base disorders. The clinical use is huge; the hemodialysis concentrate contains Harmful indicators - the content of endotoxin determines the quality of hemodialysis concentrate, and the quality of hemodialysis concentrate determines the quality of life of hemodialysis patients; the endotoxin index of domestic hemodialysis concentrate is ≤0.5EU / ml, while The international index is ≤0.25EU / ml. Studies have shown that the chronic poisoning of many hemodialysis patients is caused by endotoxi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/14
Inventor 孙维芳刘志敏岳文华
Owner 吉林省富生医疗器械有限公司
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