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Breast injectant used for preventing and treating dry-milk-period dairy cow mastitis and preparation method thereof

A technology of dry milk cow and udder injection, which is applied in the field of new veterinary drugs, can solve the problems of unsatisfactory treatment effect, lack of broad spectrum, short action time, etc., achieve significant antibacterial effect, no toxic side effects, and repair breasts organization effect

Inactive Publication Date: 2014-01-01
SOUTH CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as penicillin, streptomycin, amoxicillin, etc. These drugs have a short action time and are only effective against Gram-negative bacteria or Gram-positive bacteria. They do not have a broad spectrum and the therapeutic effect is not ideal
Although there are multiple compound breast injections abroad, such as the ampicillin-benzathine cloxacillin breast injection developed by British NORBROOK Company, the compound amoxicillin breast injection developed by Pfizer, etc., these products are only effective for specific Bacterial infections have a certain preventive effect, and most of them are expensive

Method used

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  • Breast injectant used for preventing and treating dry-milk-period dairy cow mastitis and preparation method thereof
  • Breast injectant used for preventing and treating dry-milk-period dairy cow mastitis and preparation method thereof
  • Breast injectant used for preventing and treating dry-milk-period dairy cow mastitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Calculated according to the formula amount of 3g, take 15mg of aluminum distearate, 2.835g of liquid paraffin, and 150mg of cefuroxime, and make the injection according to the following steps:

[0031] (1) Pour aluminum distearate into the dispersing emulsifier (magic LAB type of IKA company in Germany), add liquid paraffin less than the formula amount, and start the emulsifier;

[0032] (2) After the emulsion in (1) is mixed evenly, add cefuroxime, and add liquid paraffin to the formula amount, and grind circularly;

[0033] (3) Check the fineness of the particles, meet the requirements (the particle size is less than 30 μm, and the particles with a particle size >15 μm do not exceed 10%), stop grinding, and the breast injection for preventing and treating mastitis in dry milk cows is obtained. It is filled with 3g per bottle, sealed and stored, and the injection finished product a is obtained.

Embodiment 2

[0035] Calculated according to the formula amount of 3g, take 30mg of aluminum distearate, 2.770g of liquid paraffin, and 200mg of cefuroxime, and make the injection finished product b according to the same steps as in Example 1.

Embodiment 3

[0037] According to the calculation of 3g formula quantity, take 60mg of aluminum distearate, 2.690g of liquid paraffin, and 250mg of cefuroxime, and make the injection finished product c by the same steps as in Example 1.

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Abstract

The invention relates to a novel veterinary drug, in particular to a breast injectant used for preventing and treating dairy cow dry-milk-period mastitis, dairy cow postpartum recessive mastitis and dairy cow subclicnical type mastitis and a preparation method of the breast injectant. The breast injectant comprises the components of cephalosporin, aluminum distearate and liquid paraffin. Compared with the prior art, the breast injectant has the advantages of being long in effect time, stable, broad in spectrum, remarkable in effect, free of toxic and side effects, low in price and free of influences on normal gestation and safety of milk quality.

Description

technical field [0001] The invention relates to a novel veterinary drug, in particular to a udder injection used for preventing and treating dry period, postpartum recessive and subclinical mastitis of dairy cows. Background technique [0002] Mastitis is a common disease in dairy cows, and about 50% of dairy cows in the world suffer from various types of mastitis. Mastitis is one of the most costly diseases of dairy cattle. It brings huge economic losses to the dairy farming industry. The direct economic loss caused by cow mastitis in the United States reaches 2 billion U.S. dollars every year, and the annual loss caused by recessive mastitis in my country is about 135 million yuan. [0003] Cow mastitis is divided into two types: clinical mastitis (also known as overt mastitis) and recessive mastitis. Mastitis is mainly caused by a variety of non-specific pathogenic microorganisms, such as bacteria, fungi, and viruses. Among them, Staphylococcus aureus, Streptococcus ag...

Claims

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Application Information

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IPC IPC(8): A61K9/107A61K31/546A61K47/44A61P15/14A61P31/04A61K47/06
Inventor 李帅鹏黄显会
Owner SOUTH CHINA AGRI UNIV
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