GMP (Good Manufacturing Practice) production process of refined fine-powder bag-brewing type ginkgo leaf product and application method thereof

Abstract

The invention relates to a GMP (Good Manufacturing Practice) production process of a refined fine-powder bag-brewing type ginkgo leaf product with medicinal slices being dry whole or broken ginkgo leaves under the item of ginkgo leaves in Chinese Pharmacopoeia 2010 and a new application method thereof. According to a measuring method under the item of ginkgo leaves, the content of total flavonoid glycosides and the content of ginkgolide in ginkgo are adopted as indexes, the experimental study on decoction and hot-water (90 DEG C) brewing is carried out on the broken ginkgo leaves (more than 10 meshes), fine powder (80 meshes) and fine powder (80 meshes) with the same weight respectively. The experimental result shows that within all the same time intervals of 2 minutes, 5 minutes, 10 minutes, 15 minutes, 20 minutes and 30 minutes, the leaching content of the two indexes of the fine powder of ginkgo leaves is obviously higher than that of the broken leaves. Therefore, when the use standard under the item of ginkgo leaves in Chinese Pharmacopoeia is executed, the product shows the obvious advantages that the application is convenient and the curative effect can be improved.

Description

technical field [0001] The invention relates to a GMP production process and a novel application method of a refined fine powder bag-type product of ginkgo biloba whose decoction pieces are dried ginkgo leaves (whole leaves or fragments) under the item of Ginkgo biloba in 2010 of the Chinese Pharmacopoeia. According to the determination method under it, taking the content of total flavonol glycosides and terpene lactones of Ginkgo biloba as indicators, decoct the same weight of Ginkgo leaf fragments (greater than 10 mesh), 80 mesh fine powder, and 100 mesh fine powder , hot water (90 o C) Experimental study on brewing. The experimental results show that: in the same time periods of 2, 5, 10, 15, 20, and 30 minutes, the leaching content of the above two indicators of ginkgo leaf fine powder is significantly higher than that of its fragment leaves. Therefore, in the implementation "Chinese Pharmacopoeia" a ginkgo biloba item usage standard, the product of the present inventio...

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Problems solved by technology

As we all know, vascular tissue, like other tissues in the human body, completes the metabolic process within a certain period, but due to the abnormal formation of new cell tissue, there are "defects" in the vascular wall itself, which is prone to inflammation and poor vasoconstriction, just like It's an old dilapidated pipe that could clog or burst at any moment

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