Preparation method of silk fibroin/graphene oxide high-concentration blended aqueous solution

Abstract

The invention relates to a preparation method of a silk fibroin / graphene oxide high-concentration blended aqueous solution. The preparation method comprises the following steps of 1, degumming silkworm cocoons, dissolving the degummed silkworm cocoons, carrying out solution dialysis to obtain a silk fibroin aqueous solution, concentrating the silk fibroin aqueous solution until a silk fibroin concentration is in a range of 10-30wt%, and taking out the concentrated silk fibroin aqueous solution, 2, blending a graphene oxide aqueous solution subjected to ultrasonic treatment and the concentrated silk fibroin aqueous solution according to a certain ratio, 3, adding a CaCl2 aqueous solution into the mixture obtained by the step 2 to adjust a calcium ion molar concentration to 0.15-0.3mol / L, and 4, sequentially carrying out concentration to obtain the silk fibroin / graphene oxide high-concentration blended aqueous solution having silk fibroin content of 50-58wt%. The preparation method has simple processes, can be operated easily and can prepare the silk fibroin / graphene oxide high-concentration blended aqueous solution. The silk fibroin / graphene oxide high-concentration blended aqueous solution can be used for dry spinning or film coating.

Description

technical field

[0001] The invention belongs to the field of composite materials, and relates to a preparation method of a silk fibroin / graphene oxide high-concentration blended aqueous solution. Background technique

[0002] Known as the "Fiber Queen", silk is one of the earliest natural proteins used by humans. It has been widely used as a material for high-end clothing for thousands of years. Nowadays, with the continuous development of spinning technology, it is related to The field of research is gradually expanding. Researchers have extracted regenerated silk fibroin from cheap and easy-to-obtain silk. This regenerated silk fibroin has excellent mechanical properties, good biocompatibility and degradability, and can be widely used in biology, medicine, Textile and other fields.

[0003] Graphene, as the thinnest but hardest nanomaterial in the world, has become a research hotspot as soon as it appeared, and graphene oxide is an important derivative of graphene. The ...