Application of white peony root extract in preparation of health food or cosmetic with anti-radiation and anti-aging effects

A technology of health food and extract, which is applied in the field of Radix Paeoniae Alba, can solve the problems that have not been disclosed, and achieve the effects of low preparation cost, high extraction efficiency, and reduced cell damage

Active Publication Date: 2014-02-19
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there is no published research on the application of the Radix Paeoniae Alba e

Method used

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  • Application of white peony root extract in preparation of health food or cosmetic with anti-radiation and anti-aging effects
  • Application of white peony root extract in preparation of health food or cosmetic with anti-radiation and anti-aging effects
  • Application of white peony root extract in preparation of health food or cosmetic with anti-radiation and anti-aging effects

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The Radix Paeoniae Alba extract provided in this embodiment is prepared by the following method:

[0043] A: Pretreatment: wash the white peony root with water, crush it, sieve it to 30-60 mesh, and weigh 1 kg;

[0044] B: Extraction: Use 8-10 kg of ethanol aqueous solution with a volume percentage of 60% to ultrasonically extract at room temperature twice, each time for 20-40 minutes, filter through a 500-800 mesh filter cloth, combine the filtrate, and concentrate the filtrate under reduced pressure to 3-5 kg ​​to obtain a concentrated solution, add 6-8 kg of water to the concentrated solution, and filter to obtain the B extract;

[0045] C: Macroporous adsorption column separation: put the B extract on the first PIPO-02 macroporous resin separation column, first use methanol water with a volume percentage of 3% and formic acid with a volume percentage of 0.2% Formic acid water is used as the mobile phase to elute 3-5kg, and then methanol water with a volume percenta...

Embodiment 2

[0048] The Radix Paeoniae Alba extract provided in this embodiment is prepared by the following method:

[0049] A: Pretreatment: wash the white peony root raw material with water, crush it, sieve it to 30-60 mesh, and weigh 10 kg;

[0050] B: Extraction: Use 80-100 kg of ethanol aqueous solution with a volume percentage of 80% ethanol to extract twice at room temperature ultrasonically, for 20-40 minutes each time, filter through a 500-800 mesh filter cloth, combine the filtrate, and concentrate the filtrate under reduced pressure to 30-50 kg to obtain a concentrated solution, add 60-80 kg of water to the concentrated solution, and filter to obtain the B extract;

[0051] C: Macroporous adsorption column separation: put the B extract on the first PIPO-02 macroporous resin separation column, first use methanol water with a volume percentage of 3% and formic acid with a volume percentage of 0.2% Formic acid water is used as the mobile phase, eluting 30-50 kg, and then methanol...

Embodiment 3

[0054] A Radix Paeoniae Alba extract, which is prepared by the following method:

[0055] A: Pre-treatment: wash the white peony root raw material with water, crush it, sieve it to 30-60 mesh, and weigh 100 kg;

[0056] B: Extraction: Use 800-1000 kg of ethanol solution with a volume percentage of 75% ethanol to extract 3 times at room temperature by ultrasonic, 20-40 minutes each time, filter with a filter cloth of 500-800 mesh, combine the filtrate, and concentrate the filtrate under reduced pressure to 300-500 kg to obtain a concentrated solution, add 600-800 kg of water to the concentrated solution, and filter to obtain the B extract;

[0057] C: Macroporous adsorption column separation: put the B extract on the first PIPO-02 macroporous resin separation column, first use methanol water with a volume percentage of 3% and formic acid with a volume percentage of 0.2% Formic acid water is used as the mobile phase to elute 300-500 kg, and then methanol water with a volume per...

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Abstract

The invention discloses an application of a white peony root extract in the preparation of health food or cosmetic with anti-radiation and anti-aging effects. The white peony root extract has an anti-UVA radiation effect and can reduce cellular damage caused by UV radiation. meanwhile, the white peony root extract has an obvious effect of inhibiting macrophage inflammatory factor expression and can play a role in anti-inflammatory and anti-aging effects. According to the invention, it is also expounded that the white peony root extract has anti-UV radiation and anti-aging effects at the cell and molecular level. In addition, the invention also discloses an optimized preparation method of the above white peony root extract which has anti-radiation and anti-aging effects.

Description

technical field [0001] The invention belongs to the technical field of Radix Paeoniae Alba, and specifically relates to the application of Radix Paeoniae Alba extract in preparing health food or cosmetics with anti-radiation and anti-aging effects. technical background [0002] In recent years, active ingredients derived from plants have been increasingly used in compositions for medicinal, therapeutic, and cosmetic purposes. At present, the plant Radix Paeoniae Alba extract is used in various medicine and health care. [0003] Aging is a physiological phenomenon, and its physiological manifestation is the decline of the functions of various organs, leading to the occurrence of various aging diseases. And the most intuitive evidence is the aging of the skin. At the molecular level, it is manifested as cellular senescence, which is a gradual event that accompanies the aging of the body. Aging not only leads to the degradation of the body's physiological functions, but also...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K36/71A61K8/97A61P39/06A61P39/00A61P17/16A61P17/18A61Q19/08A61Q17/04A23L33/00
CPCA23L33/105A23V2002/00A61Q17/04A61Q19/08A23V2200/30A23V2200/302A23V2250/21
Inventor 赵宏伟王一飞吴志韻袁晓邹士玉马忠华
Owner INFINITUS (CHINA) CO LTD
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