Preparation method of levocarnitine freeze-dried powder for injection
A technology for freeze-dried powder and injection, which is applied in the field of preparation of levocarnitine freeze-dried powder for injection, which can solve the problem of uneven quality of levocarnitine freeze-dried powder, not very standardized process control, and inaccurate parameter control and other issues, to achieve the effect of being suitable for promotion, improving the shelf life, and standardizing the process
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[0026] In order to better understand the present invention, the following examples are used to further specifically illustrate the present invention, but it should not be understood as a limitation of the present invention. For those skilled in the art, some non-essential improvements and adjustments made based on the above-mentioned content of the invention, It is also deemed to fall within the protection scope of the present invention.
[0027] According to the method provided by the present invention, the following operations are performed:
[0028] First, prepare the following parts by weight:
[0029] 500g L-carnitine, 600g mannitol, 3500g water for injection, 7g activated carbon, and then use the following steps:
[0030] a. Weigh 70% of the prepared amount of water for injection into the mixing tank and cool to room temperature.
[0031] b. Add the approved amount of mannitol and levocarnitine, stir until completely dissolved, and adjust the pH to 5.7-6.8 with hydrochloric acid....
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