Runing tablet and preparation method thereof

Abstract

The invention provides a runing tablet. The runing tablet is prepared by compressing, pelletizing and tabletting the following raw materials in parts by weight: 320 parts of asparagus and 10-30 parts of a dispersant. The invention further provides a preparation method of the runing tablet. The preparation method disclosed by the invention has the advantage that the preparation method avoids a problems that drug quality and drug appearance are affected by poor friability, poor hardness, uneven surface and difficulty in coating of the tablet as particles prepared by other pelletizing method are coarse in surface and large in specific surface area or loose in texture, small in bulk density, and the like. The runing tablet prepared by the preparation method disclosed by the invention is good in anti-wettability, uniform in content, stable in tablet weight difference, large in hardness, good in friability and smooth and beautiful in tablet surface.

Description

technical field [0001] The invention relates to a Runing tablet. Background technique [0002] At present, the granulation methods generally adopted by traditional Chinese medicine pharmaceutical companies include wet granulation, dry granulation, spray granulation, fluidized bed granulation, etc. Among them, wet granulation includes various methods such as screw extrusion granulation, shaking granulation, high-speed stirring granulation and so on. Production Select the appropriate granulation method according to the characteristics of the required granules. As a processing process of particles, granulation can achieve the corresponding purpose required by a certain process or dosage form, and is related to the preparation and quality of almost all solid preparations. The granules produced can be final shaped products or intermediates. For example, granules, micropills, drop pills, etc. must be formed by granulation; tablets, capsules, etc., need to use granulation to impr...

AI Technical Summary

Problems solved by technology

The disadvantage is that there are many fine powders of medicinal materials in this product, and the compressibility of the particles prepared by conventional methods is poor, which makes it difficult for the hardness, friability, and weight difference of the tablet to meet the standards, and the surface of the compressed tablet is uneven, which affects the quality of the tablet. product quality

This product has a strong bitter and pungent taste, large dosage, long medication time, large tablet size, difficulty in swallowing, poor patient compliance, and difficult to guarantee drug efficacy

Images