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Antrodia camphorata extraction method, antrodia camphorata oral liquid and preparation method of antrodia camphorata oral liquid

Antrodia cinnamomea oral liquid and extraction method technology are applied in pharmaceutical formulations, medical preparations containing active ingredients, organic active ingredients, etc., and can solve problems such as single active ingredient, scarce active ingredients in supernatant liquid, and short liquid fermentation period of Antrodia cinnamomea , to achieve the effect of high efficacy and absorption rate and rich content

Active Publication Date: 2014-03-26
SHENZHEN RENTAI BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Most of the existing Antrodia oral liquids are directly concentrated from the Antrodia cinnamomea liquid fermentation liquid. The Antrodia cinnamomea liquid fermentation cycle is short and the active ingredients are single, and the active ingredients in the supernatant are even rarer, mainly water-soluble exopolysaccharides
The core pharmacological components of Antrodia Antrodia are triterpenoids and polysaccharides. Most of the triterpenoids contained in Antrodia Antrodia are fat-soluble, and the polysaccharides contained in Antrodia Antrodia are mainly concentrated in the cells. Therefore, the existing preparation process of Antrodia Antrodia Oral Liquid greatly wastes the activity of Antrodia Antrodia. Element

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0106] Specifically, the preparation method of the sugar-type Antrodia camphorata oral liquid comprises the following steps:

[0107] (1) Pectin, gellan gum, xanthan gum, powdered ethanol extract of Antrodia camphorata (if powdered water extract of Antrodia camphorata is used, add here together with powdered ethanol extract of Antrodia camphorata) , acesulfame-K, stevia, aspartame and sucralose are pre-mixed evenly, and slowly added to fructose syrup and honey while stirring, fully dispersed and dissolved, and the first part of the material is obtained after colloid milling;

[0108] (2) Mix β-glucan, fucoidan, arabinose, and sucrose evenly to obtain the second part of the material;

[0109] (3) Add the water extract of Antrodia camphorata according to the prescription (if the powdered water extract of Antrodia camphorata is used, add the amount of water in the oral liquid formula here) and heat to 80-90 degrees, at a speed of 100-150 rpm Under the condition of 10 minutes, sl...

Embodiment 1

[0117] Example 1: Sugar-free Antrodia Antrodia Oral Liquid

[0118] The formula of sugar-free Antrodia camphorata oral liquid, by weight percentage, its raw material composition is as follows:

[0119] Antrodia camphorata raw material 3%; β-glucan 2%; fucoidan 2%; arabinose 2%; polydextrose 2%; sucralose 0.001%; ​​aspartame 0.001%; Honey 0.001%; ​​xanthan gum 0.01%; gellan gum 0.01%; pectin 0.01%; the balance is water.

[0120] 1. Extraction process of Antrodia camphorata

[0121] Take the fruiting body of Antrodia camphorata, wash and chop.

[0122] According to the mass ratio of Antrodia camphorata raw material: pure water = 1:10, add the Antrodia camphorata raw material and water, extract at 95°C for 40 minutes, filter, and take the filtrate; add water 10 times the quality of the Antrodia camphorata raw material, in Extract at 95°C for 40 minutes, filter to obtain the filtrate; repeat the previous step once more; combine the filtrates obtained three times to obtain the w...

Embodiment 2

[0149] Embodiment 2: preparation of sugar-type Antrodia camphorata oral liquid

[0150] The formula of Antrodia Antrodia Oral Liquid, by weight percentage, is as follows:

[0151] Antrodia camphorata raw material 4%; β-glucan 4%; fucoidan 4%; arabic 4%; fructose syrup 4%; sucrose 4%; honey 4%; sucralose 0.01%; aspartame 0.01% ; Stevia 0.01%; Acesulfame K 0.01%; Xanthan gum 0.5%; Gellan gum 0.5%; Pectin 0.5%;

[0152] 1. Extraction process of Antrodia camphorata

[0153] Take the fruiting body of Antrodia camphorata, wash and chop.

[0154]According to the volume ratio of Antrodia camphorata raw material: pure water = 1:10, add Antrodia camphorata raw material and water, extract at 80°C for 60 minutes, filter, and take the filtrate; then extract 10 times the volume of water at 80°C for 60 minutes Minutes, filter to obtain the filtrate; repeat the previous step once more; combine the filtrates obtained three times to obtain the water extract of Antrodia camphorata. Concentra...

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PUM

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Abstract

The invention discloses an antrodia camphorata extraction method, antrodia camphorata oral liquid and a preparation method of the antrodia camphorata oral liquid. An antrodia camphorata extractive in the antrodia camphorata oral liquid is prepared by taking antrodia camphorata sporocarp or mycelium as an antrodia camphorata raw material. The antrodia camphorata oral liquid extracted from the antrodia camphorata sporocarp and mycelium tends to be natural. In order to extract effective components of the antrodia camphorata to a maximum extent, the antrodia camphorata extraction method comprises the steps of performing hot water extraction and ethanol extraction for the antrodia camphorata raw material in sequence, then processing extraction solutions obtained by the two steps, and adding the extraction solutions into the antrodia camphorata oral liquid according to a technical science. In order to improve medical effects of the antrodia camphorata, effective substances such as beta-glucan, fucoidin, arabinose, and the like are further added into the antrodia camphorata oral liquid and used for cooperating with the medical effects of the antrodia camphorata, so that the absorption rate and the effects of the antrodia camphorate oral liquid are maximized.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to an extraction method of Antrodia camphorata, oral liquid of Antrodia camphorata and a preparation method thereof. Background technique [0002] Most of the existing Antrodia oral liquids are directly concentrated from the Antrodia camphorata liquid fermentation liquid. The Antrodia camphorata liquid fermentation cycle is short and the active ingredient is single, and the active ingredients in the supernatant are even rarer, mainly water-soluble exopolysaccharides. The core pharmacological components of Antrodia Antrodia are triterpenoids and polysaccharides. Most of the triterpenoids contained in Antrodia Antrodia are fat-soluble, and the polysaccharides contained in Antrodia Antrodia are mainly concentrated in the cells. Therefore, the existing preparation process of Antrodia Antrodia Oral Liquid greatly wastes the activity of Antrodia Antrodia. Element. [0003] The Antrodia camph...

Claims

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Application Information

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IPC IPC(8): A61K36/07A61P35/00A61P37/04A61K31/716A61K31/715A61K31/7004
Inventor 赵宗杰杨如钢谢海涛周荣灵
Owner SHENZHEN RENTAI BIOLOGICAL TECH
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