Sharpleaf galangal fruit composition for treatment of acute or chronic gastroenteritis and preparation method thereof

A kind of composition, the technology of Nourishing Kernel, applied in the field of pharmacy

Active Publication Date: 2014-04-16
HAINAN FANSI TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, preparing a composition with clear components and stable quality from Yizhiren for the prevention and treatment of acute and chronic gastroenteritis has not been reported yet.

Method used

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  • Sharpleaf galangal fruit composition for treatment of acute or chronic gastroenteritis and preparation method thereof
  • Sharpleaf galangal fruit composition for treatment of acute or chronic gastroenteritis and preparation method thereof
  • Sharpleaf galangal fruit composition for treatment of acute or chronic gastroenteritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Take 400g of Yizhiren, add 3200ml of 70% ethanol, heat and reflux to extract twice, each time for 1h, filter and collect the filtrate; add distilled water to adjust the alcohol content to 50%, put on D101 macroporous resin, and wash with 50% ethanol 3000ml first Remove impurities, continue to elute with 90% ethanol, and recover ethanol from the 90% ethanol eluent with a rotary evaporator until the extract has no alcohol smell and becomes a thick paste, so as to obtain the nootropic kernel composition.

Embodiment 2

[0052]Take 400g of Yizhiren, add 4000ml of 90% ethanol, heat and reflux for extraction twice, each time for 1h, and collect the filtrate by filtration; Remove impurities, continue to elute with 90% ethanol, and recover ethanol with a rotary evaporator for the 90% ethanol eluent until the extract has no alcohol smell and becomes a thick paste to obtain the Nootropic kernel composition.

Embodiment 3

[0054] Take 400g of Yizhiren, add 5000ml of 80% ethanol, heat and reflux for extraction twice, each time for 1h, and collect the filtrate by filtration; 3000ml elution, remove impurity, continue to elution with 95% ethanol, 95% ethanol eluent reclaims ethanol with rotary evaporator until the extract has no alcohol smell and becomes thick paste, obtains the composition of nutraceuticals.

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PUM

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Abstract

A sharpleaf galangal fruit composition for treatment of acute or chronic gastroenteritis and a preparation method thereof are disclosed. The invention relates to a composition obtained by sharpleaf galangal fruit and application thereof in drug preparation, and belongs to the field of medicines. HPLC (High Performance Liquid Chromatography) analysis shows that the extract mainly contains 8 compounds, and has a good inhibition effect on mice diarrhea caused by folium sennae, and shows that the composition has a good therapeutic effect on the gastroenteritis.

Description

Technical field: [0001] The invention relates to a composition for treating acute and chronic gastroenteritis extracted and separated from Yizhiren and its application in preparing medicine, which belongs to the field of pharmacy. Background technique: [0002] Yizhiren is the dry and mature fruit of Alpinia oxyphylla Miq., a plant of the ginger family. It is mainly produced in Hainan and Guangdong in my country, and is one of the four major southern medicines. Yizhi has a wide range of pharmacological activities. Current research data show that Yizhi can antagonize calcium ion activity, anti-tumor effect, anti-aging effect, anti-allergic effect, inhibit the production of NO in cells and degranulation, and affect the nervous system. In the traditional application of Yizhi, it is mainly based on warming the spleen to stop diarrhea and consolidating essence and shrinking urine. In modern Chinese medicine clinics, it is also multi-purposed for diarrhea caused by deficiency and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P1/12
Inventor 张俊清李永辉王生魏娜
Owner HAINAN FANSI TECH CO LTD
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