Stachyose effervescent tablet and preparation method thereof
A technology of stachyose and effervescent tablets, applied in the field of effervescent tablets, which can solve the problems of high production cost, inconvenient carrying, and poor taste, and achieve the effects of high safety, inhibition of production and absorption, and low sweetness
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preparation example Construction
[0032] The preparation method of above-mentioned lactobacillus plantarum powder is as follows:
[0033] (1) Strain activation: under aseptic conditions, the Lactobacillus plantarum ( Lactobacillus plantarum ) The preservation number is CGMCC No.8212 strain, and one loop was inoculated on the solid MRS medium with an inoculation loop, and cultured in a 35-40°C incubator for 16-24 h;
[0034] (2) Inoculate 2-3 loops of the activated Lactobacillus plantarum into 100mL liquid MRS medium, and incubate in a 36-38°C incubator for 10-12 hours;
[0035] (3) Inoculate the bacterial solution obtained in step (2) into 1L of solid MRS medium at an inoculum volume of 5%; culture in a 36-38°C incubator for 12-14 hours, collect the bacterial cells by centrifugation at 5000rpm, discard Add 10mL of sterilized freeze-drying protective agent to the supernatant fermentation liquid, put it in a -80°C refrigerator for 24 hours, and freeze-dry it for 24 hours, that is, Lactobacillus plantarum powder...
Embodiment 1
[0041] A stachyose effervescent tablet is composed of the following ingredients and their weight percentages: 11% stachyose, 64% disintegrant, 17.5% sweetener, 3% binder, 3.5% lubricant, 0.65% cooling agent , 0.15% essence, 0.1% Lactobacillus plantarum powder. The specific preparation method is as follows: pass stachyose, disintegrant, sweetener, binder, lubricant, cooling agent and essence through an 80-mesh sieve, mix according to the above mass percentage, and then air-dry at 45°C for 4 hours , passed through a 14-mesh sieve for granulation, added Lactobacillus plantarum powder, then compressed into tablets at a relative humidity of 40% and a temperature of 18°C, dried at 37°C, and packaged to obtain stachyose effervescent tablets finished product.
[0042] In this specific example, the disintegrating agent is mixed with sodium bicarbonate and citric acid in a mass ratio of 1:1.35; the sweetener is sucralose, sorbitol, xylitol, and erythritol Any one of them is mixed at a...
Embodiment 2
[0048] A stachyose effervescent tablet is composed of the following ingredients and their weight percentages: 15% stachyose, 60% disintegrant, 15% sweetener, 4% binder, 4.5% lubricant, 1.1% cooling agent , 0.2% essence, 0.2% Lactobacillus plantarum powder. The specific preparation method is as follows: pass stachyose, disintegrant, sweetener, binder, lubricant, cooling agent and essence through an 80-mesh sieve, mix according to the above mass percentage, and then air-dry at 45°C for 4 hours , passed through a 14-mesh sieve for granulation, added Lactobacillus plantarum powder, then compressed into tablets at a relative humidity of 35% and a temperature of 15°C, dried at 38°C, and packaged to obtain stachyose effervescent tablets finished product.
[0049] In this specific embodiment, sodium bicarbonate and citric acid are mixed in a ratio of 1:1.2 by mass; the sweetener is any two of sucralose, sorbitol, xylitol, and erythritol. The above combination is mixed at a mass rati...
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