A kind of stachyose effervescent tablet and preparation method thereof
A technology for stachyose and effervescent tablets, applied in the field of effervescent tablets, can solve the problems of inconvenience to carry, poor taste and high production cost, and achieve the effects of inhibiting production and absorption, low sweetness and high safety
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preparation example Construction
[0032] The preparation method of above-mentioned lactobacillus plantarum powder is as follows:
[0033] (1) Strain activation: under aseptic conditions, the Lactobacillus plantarum ( Lactobacillus plantarum ) The preservation number is CGMCCNo.8212 strain, one loop was inoculated on the solid MRS medium with an inoculation loop, and cultured in a 35-40°C incubator for 16-24 hours;
[0034] (2) Inoculate 2-3 loops of the activated Lactobacillus plantarum into 100mL liquid MRS medium, and incubate in a 36-38°C incubator for 10-12 hours;
[0035] (3) Inoculate the bacterial solution obtained in step (2) into 1L of solid MRS medium at an inoculum volume of 5%; culture in a 36-38°C incubator for 12-14 hours, collect the bacterial cells by centrifugation at 5000rpm, and discard Clear the fermentation broth, add 10mL sterilized freeze-drying protective agent to the bacteria, freeze in a -80°C refrigerator for 24 hours, freeze-dry for 24 hours, that is, Lactobacillus plantarum powder...
Embodiment 1
[0041] A stachyose effervescent tablet is composed of the following ingredients and their weight percentages: 11% stachyose, 64% disintegrant, 17.5% sweetener, 3% binder, 3.5% lubricant, 0.65% cooling agent , 0.15% essence, 0.1% Lactobacillus plantarum powder. The specific preparation method is as follows: pass stachyose, disintegrant, sweetener, binder, lubricant, cooling agent and essence through an 80-mesh sieve, mix according to the above mass percentage, and then air-dry at 45°C for 4 hours , passed through a 14-mesh sieve for granulation, added Lactobacillus plantarum powder, then compressed into tablets at a relative humidity of 40% and a temperature of 18°C, dried at 37°C, and packaged to obtain stachyose effervescent tablets finished product.
[0042] In this specific example, the disintegrating agent is mixed with sodium bicarbonate and citric acid in a mass ratio of 1:1.35; the sweetener is sucralose, sorbitol, xylitol, and erythritol Any one of them is mixed acco...
Embodiment 2
[0048] A stachyose effervescent tablet is composed of the following ingredients and their weight percentages: 15% stachyose, 60% disintegrant, 15% sweetener, 4% binder, 4.5% lubricant, 1.1% cooling agent , 0.2% essence, 0.2% Lactobacillus plantarum powder. The specific preparation method is as follows: pass stachyose, disintegrant, sweetener, binder, lubricant, cooling agent and essence through an 80-mesh sieve, mix according to the above mass percentage, and then air-dry at 45°C for 4 hours , passed through a 14-mesh sieve for granulation, added Lactobacillus plantarum powder, then compressed into tablets at a relative humidity of 35% and a temperature of 15°C, dried at 38°C, and packaged to obtain stachyose effervescent tablets finished product.
[0049] In this specific embodiment, sodium bicarbonate and citric acid are mixed in a ratio of 1:1.2 by mass; the sweetener is any two of sucralose, sorbitol, xylitol, and erythritol. The above combination is mixed at a mass rati...
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