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Strains of lactic acid bacteria and/or bifidobacteria inhibiting/reducing the growth of different biotypes of E. coli and different biotypes of clostridia

A technology of Escherichia coli, Bifidobacterium breve, applied in the field of lactic acid bacteria and Bifidobacterium strains, which can solve the problems of harmful antibiotic use, imbalance, prevalence of spoilage species, etc.

Inactive Publication Date: 2014-05-28
PROBIOTICAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The pathogenesis usually caused by Clostridium difficile is associated with the use of antibiotics that cause a marked imbalance in the intestinal microbial flora, predisposing to the prevalence of putrefactive species to the detriment of those bacteria that are fermentative

Method used

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  • Strains of lactic acid bacteria and/or bifidobacteria inhibiting/reducing the growth of different biotypes of E. coli and different biotypes of clostridia
  • Strains of lactic acid bacteria and/or bifidobacteria inhibiting/reducing the growth of different biotypes of E. coli and different biotypes of clostridia
  • Strains of lactic acid bacteria and/or bifidobacteria inhibiting/reducing the growth of different biotypes of E. coli and different biotypes of clostridia

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Embodiment Construction

[0036] Applicants have conducted extensive research and initiated screening from a very broad panel of bacterial strains. At the end of this work, the applicant discovered and selected the Lactobacillus delbrueckii, Lactobacillus delbrueckii subsp. delbrueckii, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus pentosus and Bifidobacterium breve Group or alternatively a group of bacterial strains of one or more species selected from the group consisting of these bacteria. Selected strains are capable of producing bacteriocins and / or metabolites and / or oxygenated water, substances that are effective against, inhibit or reduce pathogenic bacteria. These strains have effective application and use in the prophylactic and / or curative treatment of infections and / or pathologies associated with Gram-negative and / or Gram-positive pathogenic bacteria.

[0037] The pathogenic bacteria are selected from the group comprising coliforms and Clostridia. Coliforms are a group of...

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Abstract

The present invention refers to strains of lactic bacteria and / or bifidobacteria having activity of inhibiting / reducing the growth of different biotypes of E. coli, including E. coli O157:7 and different biotypes of clostridia, including Clostridium difficile, Listeria monocytogenes, Enterococcus sp. and Klebsiella sp. Furthermore, the present invention refers to a pharmaceutical or dietary composition or a supplement or a medical device comprising at least one of the said strains of bacteria, optionally in combination with acetylcysteine and / or microencapsulated gastroprotected lysozyme and / or acetylcysteine with microencapsulated gastroprotected lysozyme.

Description

technical field [0001] The present invention relates to lactic acid bacteria and bifidobacteria strains which have the ability to inhibit / reduce different biotypes of Escherichia coli (E. coli) (Gram-negative) including E. coli O157:H7 and O104:H4 Role of different bacterial species (Clostridium difficile) belonging to the family Clostridiaceae (anaerobic, Gram-positive, rod-shaped) for endoinfection. [0002] Furthermore, the invention relates to resistance to Listeria monocytogenes (Gram positive), Enterococcus sp. and Klebsiella sp. (Gram Negative), lactic acid bacteria strains with specific antibacterial activity. The invention also relates to a pharmaceutical or dietary composition or supplement or medical device comprising at least one of said strains of lactic acid bacteria and / or bifidobacteria, optionally in combination with acetylcysteine ​​and / or lysozyme. Background technique [0003] Escherichia coli (abbreviated E.coli) is known as a species of the well-known...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/74A23L1/30A61K35/745A61K35/747
CPCA61K38/47A61K35/747A61K35/745C12Y302/01017A23L1/3014A23L1/308A61K9/48A23L1/305A61K31/198C12N1/20A23L1/3051A61K47/44A23L33/135A23L33/17A23L33/175A23L33/21A61P31/04Y02A50/30A61K2300/00A23V2002/00A23V2400/167A23V2400/175A23V2400/169
Inventor G·莫格纳
Owner PROBIOTICAL
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