Method for preparing glabridin microcapsules by virtue of complex coacervation-spray drying process

Abstract

The invention discloses a method for preparing glabridin microcapsules by virtue of a complex coacervation-spray drying process. The method comprises the following steps: heating and dissolving to-be-compounded wall materials by using deionized water, then proportionally mixing so as to form a compound wall material solution, then proportionally adding a core material, namely a glabridin extractive, mixing and uniformly stirring so as to obtain a mixed solution; homogenizing and emulsifying the obtained mixed solution so as to obtain an emulsion, and then adding formaldehyde so as to solidify the emulsion so as to obtain a glabridin microcapsule solution; carrying out spray drying on the obtained glabridin microcapsule solution so as to form powder, thus obtaining the glabridin microcapsules. The method has the advantages that the glabridin is wrapped by the compound wall materials, the color of the prepared microcapsules is greatly dodged, after the glabridin microcapsules are added to cosmetic systems, cosmetics do not change in color, and the glabridin microcapsules are compatible with other components in the cosmetic formula and have no influences on the product appearance. The intense smell of microencapsulated glabridin is also alleviated thereupon; the glabridin microcapsules serve as a cosmetic additive; the preparation process is simple, convenient and practicable; the industrial production is easy.

Description

Technical field: [0001] The invention belongs to the technical field of microencapsulation of biologically active functional substances to change physical properties and appearance, and specifically relates to a method for preparing glabridin microcapsules by a composite coacervation-spray drying method. Background technique: [0002] Microcapsule technology is a technology that wraps solid or liquid with easy-to-film-forming materials to form tiny particles. The resulting tiny particles are called microcapsules, and the diameter of the particles is generally in the order of microns or millimeters. The substance wrapped inside the microcapsule is called the core material (or clathrate, capsule core, etc.), the core material can be solid, liquid or gas, and the coating film formed by the easy-to-film-forming material outside the microcapsule is called the wall material ( Or outer membrane, capsule wall), according to the nature, state and use of the core material to be wrapp...

AI Technical Summary

Problems solved by technology

But this method has its defect again: (1) core material material can be adsorbed on the surface of microcapsule, easily causes oxidation; It has a porous structure and cannot prevent the entry of oxygen, and the shelf life of the product is short; (3) the microcapsule wall membrane is fragile and porous, which is not suitable for the preparation or controlled release of microcapsules

However, the content of glabridin in Glycyrrhiza glabra is only 0.1% to 0.3%, and it is difficult to extract

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