Dental medicinal membrane and preparation method thereof

Abstract

The invention discloses a dental medicinal membrane. The dental medicinal membrane comprises the following components by weight: 3-8g of clotrimazole, 3-8g of dyclonine, 1-3g of metronidazole, 0.3-0.6g of dexamethasone, 10-18g of CMC-Na (sodium carboxymethylcellulose), 40-60g of sodium alginate, 12-18g of tragacanth, 100-150g of ethanol and 1,000-1,500g of purified water. The invention also provides preparation of the dental medicinal membrane, which comprises the following steps: (1) soaking the sodium alginate with ethanol, and grinding in a mortar for later use; (2) naturally peptizing the tragacanth and CMC-Na in the purified water; (3) dissolving the clotrimazole and metronidazole in ethanol, and slowly adding the solution into the mortar in the step (1); dissolving the dexamethasone and metronidazole in the purified water, mixing with the solution in the step (2), slowly adding the mixture into the mortar in the step (1), and constantly grinding to obtain a colloidal liquid; and (4) preparing a membrane from the colloidal liquid, drying and subpackaging. The dental medicinal membrane is low in cost, simple in preparation method and remarkable in treatment effect, and has the effects of inhibiting bacteria and diminishing inflammation; and the dental medicinal membrane is an external application, and is applied to an affected part.

Description

technical field [0001] The invention relates to an oral medicine film and a preparation method thereof, belonging to the technical field of medicine preparation. Background technique [0002] Oral ulcer, also known as "oral sore", is a disease of the department of stomatology. The size can range from rice grains to soybeans, and it is round or oval. The ulcer surface is concave and the surrounding is congested. Ulcers have the characteristics of periodicity, recurrence and self-limitation, and are prone to occur on the lips, cheeks, and tongue margins. With the prolongation of the course of the disease, many patients have enlarged ulcer area and number, aggravated pain, prolonged healing period, and shortened interval, which affect eating and speaking. Various powders for external use currently sold in the market have a slow curative effect and cannot heal ulcers quickly and effectively. [0003] There are many factors that cause oral ulcers, such as oral ulcers caused by ...

AI Technical Summary

Problems solved by technology

Various powders for external use currently on the market have slow curative effects and cannot heal ulcers quickly and effectively

[0003]There are many factors that cause oral ulcers, such as oral ulcers caused by excessive fatigue; internal factors such as endocrine disorders and decreased autoimmunity; genetic factors, high mental pressure, work External factors such as fatigue and frequent insomnia; some people also believe that oral ulcers are directly related to genetics, hormones and other factors. For example, oral ulcers in women tend to worsen before menstruation, and menopausal women are more likely to suffer from oral ulcers, but pregnant women It is not easy to suffer from oral ulcers. These phenomena all show that the occurrence of ulcers is directly related to the changes in hormone levels in the body; although many methods for treating oral ulcers have many advantages, some shortcomings will lead to difficulties in clinical promotion. For example, the application of rhG -GSF saline in the treatment of oral ulcers caused by chemotherapy drugs, although the curative effect is obvious, but due to the high price of rhG-CSF drugs, it is very difficult for poor families to pay for disease chemotherapy, and it is impossible for them to spend expensive The price is to buy rhG-CSF separately for mouthwash, so the high cost of the treatment method is also a limiting factor for clinical promotion