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Ultrasonic atomization steam inhalation treatment method of ephedrine composition

A technology of ultrasonic atomization and treatment method, which is applied in the direction of medical formula, drug combination, drug delivery, etc. It can solve the problems of delaying the therapeutic effect and achieve the effects of improving ventilation and drainage, increasing the clearance rate of cilia, and easy discharge

Inactive Publication Date: 2014-07-16
SHANGHAI PUDONG INTPROP PROTECTION ASSOC
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  • Abstract
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AI Technical Summary

Problems solved by technology

Since the active ingredient is indirectly provided through the digestive system and absorbed into the blood, as all active ingredients for oral administration, the onset of therapeutic action is delayed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0013] Composition of the present invention is prepared with following method:

[0014] 1, the preparation of ephedrine composition:

[0015] In a steam-jacketed stainless steel mixing kettle of appropriate size, add 330.8 grams of menthol crystals and 330.8 grams of camphor crystals, cover the kettle loosely, and heat the contents to melt the crystals while maintaining the temperature of the molten liquid at approx. 52°C. While melting, the menthol and camphor mixture was stirred occasionally, and when the crystals were completely melted, 223.8 grams of methyl salicylate and 87.6 grams of ephedrine were added to the melt. Heating was discontinued and the solution was allowed to cool to ambient temperature with occasional stirring. When the solution has cooled completely to ambient temperature, it is placed in a suitable amber glass container and closed.

[0016] The solution contains the following components (by weight):

[0017] Ephedrine 9.0%

[0018] Methyl salicy...

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PUM

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Abstract

The invention relates to a method for providing ephedrine in a gas-phase manner, wherein the ephedrine composition contains ephedrine and salicylic acid alkyl ester, preferably the salicylic acid alkyl ester is methyl salicylate, and the non-mandatory component in the composition comprises an aromatic compound such as camphor, menthol and various other essence oils. According to the method, during treatment of nasal congestion and bronchial asthma, the gas-phase manner is adopted to provide ephedrine and other treatment drugs for lesions, and the drug atomization steam inhalation treatment manner is adopted to help the drug to be rapidly absorbed into the lesion through steam so as to effectively and quickly kill viruses and bacteria, treat inflammation and congestion conditions, and improve and recover pathogenetic conditions.

Description

technical field [0001] The invention relates to a method for treating nasal congestion and bronchial asthma by adopting an ephedrine composition, in particular to an ultrasonic atomization steam inhalation treatment method of the ephedrine composition. Background technique [0002] The common cold is generally accompanied by discharge of fluid from the nose (runny nose), sneezing, coughing, headache, and congestion in the nose, bronchi, and lungs. One or more of these symptoms are generally relieved by systemic or topical administration of appropriate medicines such as cold tablets or capsules, external cold medicines, nasal drops, nasal sprays, steam inhalers or other medicines. It has been known that ephedrine (hereinafter referred to as ephedrine) can be used to treat various physiological diseases, including cold symptoms and other nasal mucosa and respiratory diseases. Other uses of ephedrine include: treatment of narrowing of blood vessels; enhancement of blood pressu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/618A61K31/137A61K47/10A61K47/08A61K9/72A61P31/04A61P31/12A61P11/02A61P11/06A61P29/00A61P11/00
Inventor 王也
Owner SHANGHAI PUDONG INTPROP PROTECTION ASSOC
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