Angelica oil transdermal patch and preparation method thereof
A technology of transdermal patch and angelica oil, applied in the field of medicine, can solve problems such as adverse effects, and achieve the effects of reducing individual differences, reducing toxic and side effects, and being convenient to use
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[0026] Example 1: (1) Heat 4g of PEG400 and 5g of PEG4000 and mix them uniformly. (2) Take 4g of angelica oil, heat and mix with the base to make angelica oil ointment. (3) Spread the ointment on the backing film (thickness 0.3mm, area 4cm x 6cm or 6cm x 8cm), cover it with EVA controlled release film (thickness 50μm), and seal it with thermoplastic. (4) The pressure-sensitive adhesive is hot-melt coated on the release layer, covering the adhesive surface outside the controlled release film. (5) Sealed and packaged in aluminum-plastic composite film bags and stored in a cool, dark place.
Example Embodiment
[0027] Example 2: (1) 4g of PEG400 and 5g of PEG4000 were heated and melted and mixed uniformly. (2) Take 4g of angelica oil, heat and mix with the base to make angelica oil ointment. (3) Spread the ointment on the backing film (thickness 0.5mm, area 4cm x 6cm or 6cm x 8cm), cover it with EVA controlled release film (thickness 50μm), and seal it with thermoplastic. (4) Coat the PEG matrix (thickness 0.2mm) on the outside of the controlled release film, then cover the release layer, and attach a medical adhesive sticker. (5) Sealed and packaged in aluminum-plastic composite film bags and stored in a cool, dark place.
Example Embodiment
[0028] Example 3: (1) Heating, melting, and mixing PEG400 40g and PEG4000 50g evenly. (2) Take 40g of angelica oil, heat and mix it with the base to make angelica oil ointment. (3) Spread the ointment on the backing film (thickness 0.4mm, area 4cm x 6cm or 6cm x 8cm), cover the EVA controlled release film (thickness 50μm), and seal it with thermoplastic. (4) Coat the PEG matrix (thickness 0.2mm) on the outside of the controlled release film, then cover the release layer, and attach a medical adhesive sticker. (5) Sealed and packaged in aluminum-plastic composite film bags and stored in a cool, dark place.
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