Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

48results about How to "Long-lasting and stable effect" patented technology

Sun block containing natural plant sun composition and preparation method thereof

The invention discloses sunscreen lotion containing natural plant sunscreen components and a preparation method thereof, which comprises A component, B component and de-ionized water; wherein, the A component comprises 5 percent to 10 percent of whiteruss, 3 percent to 8 percent of octodecyl alcohol, 3.5 percent to 6 percent of stearic acid, 0.6 percent to 1.2 percent of sodium lauryl sulfate and 0.1 percent to 0.2 percent of nipagin methyl ester; the B component comprises 6 percent to 9 percent of glycerin, 1 percent to 3 percent of Chinese traditional medicine ingredients, 0.3 percent to 0.5 percent of essence and 0.1 percent to 0.2 percent of nipagine propyl ester; the Chinese traditional medicine ingredients per gram is composed of 0.15 gram to 0.30 gram of flos sophora, 0.50 gram to 0.75 gram of honeysuckle and 0.10 gram to 0.20 gram of peony. When the sunscreen cream is prepared, the Chinese traditional medicine is firstly prepared. Secondly, the A and the B components are respectively heated to about 80 DEG C to be melted, the A component is added into the B component along with stirring, and then the de-ionized water is added into the mixture. The fast stirring can not stop until the mixture is emulsified completely, and then the mixture is cooled to obtain the sunscreen lotion containing natural plant sunscreen components. The invention has broad-spectrum function to UV-A and UV-B rays and compensates the deficiency of a single component, and has favorable effect on absorbing ultraviolet radiation.
Owner:NANJING UNIV OF INFORMATION SCI & TECH

Slow-release patch with daphne giraldii bark extract, and preparation method thereof

The invention belongs to the technical field of medicament, and discloses a percutaneous slow-release patch with a daphne giraldii bark extract, and a reparation method thereof. The patch with the daphne giraldii bark extract comprises a back lining layer, a drug reservoir and an antisticking layer, wherein the drug reservoir consists of the daphne giraldii bark extract, pressure sensitive adhesive and a percutaneous absorption accelerator; plasticizer, tackifier and antioxidant and the like can be added if needed; the selected pressure sensitive adhesive is silicone pressure sensitive adhesive, isobutylene pressure sensitive adhesive or acrylate pressure sensitive adhesive, and can select one or more compounds therein. The percutaneous patch has the advantages that the percutaneous patch can prevent oral administration from causing liver first-pass effect and irritating gastrointestinal tracts, overcomes deficiency that ointment, plaster, liniment, cream and other preparations are uncertain in dosage, easy to pollute clothes and the like, is constant in drug-releasing speed, ensures lasting steady therapeutic effect, and is convenient to use, good in flexibility and suitable in adhesion. The 24-hour accumulated permeation amount of daphnetin in a daphne giraldii bark patch prepared by the method is obviously higher than that of the commercially available daphne giraldii bark plaster.
Owner:SHENYANG PHARMA UNIVERSITY

Tamsulosin hydrochloride double-layer osmotic pump controlled-releasing tablet and preparation method thereof

The invention provides double-layer osmotic pump tablets of tamsulosin ehydrochloride and a process for preparation. The medicament contains tamsulosin ehydrochloride and acceptable medical polymeric excipient, and is characterized in that the invention has excellent zero-level controlled releasing, pH level of environment, movements of the stomach and intestine, and food, has little effect on releasing action and food, and has no effect on the internal pharmacokinetics parameter. According to the percentage by weight, the preparation contains tamsulosin ehydrochloride 0-2%, excipient in pastille layer with the function of controlled-releasing 30-70% excipient in boosting layer with the function of controlled releasing 30-70%, and the rest percentage of other excipient. The of process for preparation the double layer permeable pump controlled-release tablets of tamsulosin ehydrochloride comprises (1) the preparation of pastille layer, (2) the preparation of boosting layer, (3) the compressing of the two layers, (4) the coating of the double layer tablets, (5) the perforating of the coated tablets, (6) the packing of moisture proof cost. The invention is clinically used for the treatment of paruria symptom like frequent micturition, diuresis at night, dysuria caused by prostatic hyperplasia.
Owner:SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI +1

Comfortable skin-protection health-care parallel spinning wrap soft yarn and preparing method thereof

The invention relates to health-care yarn, in particular to comfortable skin-protection health-care parallel spinning wrap soft yarn and a preparing method and application thereof. The comfortable skin-protection health-care parallel spinning wrap soft yarn is novel composite yarn and is mainly provided with unidirectional wrap composite soft yarn and bidirectional cross wrap composite soft yarn and comprises core yarn, outer wrap yarn and rough yarn, wherein water-soluble polyvinyl alcohol staple fiber filament is adopted by the outer wrap yarn; polymer filament is adopted by the core yarn; the rough yarn is one or more of fine staple cotton fiber and original-color or color pearl fiber. The health-care parallel spinning wrap soft yarn is novel composite yarn and has the advantages of being bright in dyed color, rich in color, high in color fastness, tender in luster, good in moisture absorption and the like, fabric processed through the health-care parallel spinning wrap soft yarn has the performance of being soft in texture, excellent in elasticity, high in water absorption, large in water storage capability, good in moisture absorption and rapid moisture-permeability, good in breathability, good in moisture permeability, good in comfort, good in heat retention and the like.
Owner:ZHONGYUAN ENGINEERING COLLEGE

Multifunctional health-care porous elastic big-belly yarn and preparation method thereof

InactiveCN107130336AReduce drag tensionImprove the finishYarnPolyesterWorsted
The invention relates to a preparation method and application of a multifunctional health-care porous elastic big-belly yarn. The multifunctional health-care porous elastic big-belly yarn is prepared from two core yarns, two fixed yarns and a decorative yarn, wherein the fixed yarns are core-spun yarns obtained by carrying out blended processing on silver fibers, copper fibers, soft silk fibers and DOW-XLA elastic fibers; the core yarns are blended hollow yarns obtained by carrying out blended processing on Porel fibers, hollow polyester fibers and provilion; the decorative yarn is a blended rough yarn obtained by carrying out blended processing on nettle fibers, apocynum fibers and alpaca wool fibers. The multifunctional health-care porous elastic big-belly yarn not only has a special form, but also is rich in yarn colors, multiple in shapes and ever-changing; products developed by using the multifunctional health-care porous elastic big-belly yarns are natural and environment-friendly, have the health care functions of resisting bacteria and eliminating inflammation, protecting skin and keeping fitness, absorbing moisture and releasing sweat, deodorizing and resisting aging, and the like, are good in comfortableness, and do not cause adverse effects when being contacted with a human body; the multifunctional health-care porous elastic big-belly yarn is mainly used for various textiles such as yarn-dyed female lines, knitted fabrics, tweed, coarse worsted fabrics, decorative articles, hand knitted fabrics and shawls.
Owner:ZHONGYUAN ENGINEERING COLLEGE

Long-acting donepezil percutaneous absorption sticking agent

The invention belongs to the technical field of medicines, and particularly provides a long-acting donepezil percutaneous absorption sticking agent. The long-acting donepezil percutaneous absorption patch agent consists of a back lining layer, a drug-containing pressure-sensitive glue layer and an anti-sticking layer, wherein the long-acting donepezil percutaneous absorption sticking agent comprises 5-15 parts of main drug donepezil, 70-95 parts of pressure-sensitive glue and 0.5-15 parts of percutaneous absorption accelerant. The long-acting donepezil percutaneous absorption sticking agent is characterized in that the ingredients of a film selected by the back lining layer comprises polyethylene, polyester and ethylvinylacetate. The donepezil percutaneous absorption sticking agent provided by the invention is stable and durable in curative effect, and each sticking agent has 5 days of effective function. The long-acting donepezil percutaneous absorption sticking agent is characterized in that the back lining layer capable of providing maximum drug-permeable quantity is adopted. The long-acting donepezil percutaneous absorption sticking agent provided by the invention is good in percutaneous permeability, durable and stable in curative effect, and good in skin feeling.
Owner:SHENYANG PHARMA UNIVERSITY

Amlodipine controlled release patch and preparing method thereof

The invention belongs to medical technique field and discloses an amlodipine controlled-release patch and a preparation method. The invention comprises a backing layer, a drug reservoir and an anti-sticking layer. The drug reservoir consists of amlodipine which is the main medicine materials, pressure sensitive adhesive and composite and percutaneous absorption enhancer; wherein, the dosage of amlodipine accounts for 0.5 to 45 wt percent of the weight of drug reservoir, the dosage of pressure sensitive adhesive accounts for 10 to 90 wt percent of the weight of drug reservoir and the dosage of the composite and percutaneous absorption enhancer accounts for 1 to 45 wt percent of the weight of drug reservoir. The invention also can be added with plasticizer, tackifier and chemical inhibitor, etc. an amlodipine controlled-release patch is a novel drug delivery system which can avoid the gastrointestinal stimulation of oral dosage and release drug slowly to relieve the side effects of the drug, and releases drug continuously for 72 hours, thereby having persistent and steady efficacy. When drug delivery needs to be interrupted, people just need to take off the patch, thereby being convenient. The invention also has the advantages of good flexibility and appropriate adhesiveness.
Owner:沈阳药大制剂新技术有限公司

Escitalopram percutaneous patch and preparation method thereof

ActiveCN104840973AEffective regulation of transdermal penetration rateSimple technologyOrganic active ingredientsNervous disorderOrganic acidEscitalopram
The invention belongs to the technical field of medicine and relates to an escitalopram percutaneous patch and a preparation method thereof. The escitalopram percutaneous patch is composed of a backing layer, a medicine-carrying pressure-sensitive adhesive layer and an anti-sticking layer, the medicine-carrying pressure-sensitive adhesive layer comprises escitalopram free alkali or organic acid ion pair compound thereof, pressure-sensitive adhesive and percutaneous absorption promoter, the escitalopram free alkali or organic acid ion pair compound thereof accounts for 2.0-20wt% of total weight of the medicine-carrying pressure-sensitive adhesive layer, pressure-sensitive adhesive accounts for 77-97wt% of the total weight, the percutaneous absorption promoter accounts for 0-6.8wt% of the total weight, and in the escitalopram organic acid ion pair compound, a ratio of escitalopram free alkali and different organic acids is 0.5:1-2:1. Compared with an escitalopram organic acid ion pair compound percutaneous absorption patch and an escitalopram free alkali percutaneous absorption patch, the escitalopram percutaneous patch has the advantages that medicine release up to seven days and similar to constant rate can be provided, so that medication compliance of a patient is improved greatly.
Owner:SHENYANG PHARMA UNIVERSITY

Pramipexole transdermal patch and preparing method thereof

The invention belongs to the technical field of medicine, and discloses a pramipexole transdermal patch and a preparing method thereof. The pramipexole transdermal patch comprises a back lining, a medicine storage library and a binding-prevention layer, wherein the medicine storage library comprises 1-20 wt% of a main medicine pramipexole, 50-90 wt% of a pressure-sensitive adhesive and 0.5-10 wt%of a transdermal absorption accelerator. An inert filler, a tackifier, an antioxidant and the like can also be added, and the dosages of the inert filler, the tackifier, the antioxidant and the like are 0.1-10 wt% separately. The pramipexole transdermal patch is a novel medicine delivery system, the situation that the medicine delivery adaptability of an injection is poor can be avoided, the irritation of the oral dosage form to the gastrointestinal tract can also be avoided, the drug is released slowly, thus the toxic and side effects of the medicine are alleviated, and the curative effect islasting and steady; if medicine delivery needs to be interrupted, what is only needed is to uncover the patch, and thus the patch is convenient to use. The pramipexole transdermal patch also has theadvantages of being good in adhesiveness and flexibility, causing no contamination and the like.
Owner:大道隆达(北京)医药科技发展有限公司

Sun cream containing natural sun-prevention component and preparation method thereof

The invention discloses sunblocking cream containing natural sunblocking ingredients and a preparation method thereof. The sunblocking cream comprises a component A, a component B and deionized water, wherein the component A consists of 8 to 12 percent of caprylic acid/caprin, 2 to 4 percent of stearic acid, 3 to 6 percent of hexadeca octadecanol, 2.5 to 6 percent of isopropyl palmitate, 1 to 1.6 percent of gyceryl monostearate, and 0.1 percent of propylparaben; the component B consists of 5 to 10 percent of natural plant ingredients, 5 to 8 percent of glycerol, 2 to 2.4 percent of cetanol ether phosphate sylvite, and 0.1 percent of methyl hydroxybenzoate; the balance being the deionized water; and 1 gram of the natural plant ingredients consist of 0.40 to 0.60 gram of grape leaf, 0.25 to 0.50 gram of sweet osmanthus and 0.10 to 0.15 gram of green tea. During the preparation, the natural plant ingredients are prepared firstly. The component A and the component B are respectively heated up to about 80 DEG C so as to be dissolved, and are stirred and mixed evenly; the deionized water is added into the component A and the component B; and the solution is stirred rapidly for complete emulsification and then is cooled down to obtain the sunblocking cream. The sunblocking cream has the advantages that the sunblocking cream has stronger absorption property for medium-wave and long-wave ultraviolet rays, and can effectively prevent the radiation of the ultraviolet rays on skin without generating any adverse reactions such as stimulus and irritability and so on.
Owner:NANJING UNIV OF INFORMATION SCI & TECH

Microcapsule Chinese herbal medicine composition capable of inhibiting bacteria, resisting inflammation and promoting blood circulation, and preparation method for microcapsule Chinese herbal medicine composition

The invention belongs to the daily chemical field. A microcapsule Chinese herbal medicine composition capable of inhibiting bacteria, resisting inflammation and promoting blood circulation is preparedfrom a microcapsule inclusion and following ingredients in parts by weight: polygoni multiflori radix, cacumen platycladi, Zingiber officinale Rosc. roots, radix angelicae sinensis, Eclipta prostrata(L.) L., Piper nigrum L seeds, capsicum annuum fructus and yeast extracts. The composition has the efficacy of resisting inflammation, inhibiting bacteria, promoting blood circulation, preventing hair loss, restoring hair and nourishing hair. According to the preparation method disclosed by the invention, various Chinese herbal medicines are mixed and extracted so as to prevent from importing excessive impurities, the high purity of the active ingredients of an extracting solution is guaranteed, and the microcapsule Chinese herbal medicine composition is moderate and inirritative. The microcapsule inclusion is adopted to carry out inclusion protection on a traditional Chinese medicine compound extracting solution and the yeast extracts, and the stability and the high activity of effectiveingredients are improved. During utilization, the microcapsule Chinese herbal medicine composition exhibits better pertinence, a higher medicine effect and an obvious effect, and a treatment period is effectively shortened.
Owner:OPAL COSMETICS HUIZHOU

Anastrozole controlled release patch and preparation method thereof

The invention belongs to the field of pharmaceutical technology, disclosing an anastrozole controlled release patch and a preparation method thereof. The invention comprises a back lining layer, a medicine reservoir and an anti-sticking layer, wherein, the medicine reservoir comprises remedium cardinale anastrozole, pressure sensitive adhesive and sorbefacient by skin, wherein, the anastrozole accounts for 0.5-30wt%, the pressure sensitive adhesive accounts for 70-90wt% and the sorbefacient by skin accounts for 0.5-50wt%; inert filler, plasticizer, tackifier, chemical inhibitor and the like can also be added to the list. The anastrozole, the pressure sensitive adhesive and the sorbefacient by skin are fully mixed and transferred to be coated on the anti-sticking layer for being dried at the temperature of 40-80 DEG C, and then the mixture are compounded by using PVC or lining materials without woven fabrics and made into the patch of different sizes and specifications by die cutting, thus obtaining the finished product. The patch can not only avoid stimulus to the gastrointestinal tract by oral medication but also reduce the toxic side effect of the medicine by slow release; the release lasts for at least 7 days, thus ensuring lasting and stable therapeutical efficiency; if medicine administration is desired to be halted, removing the patch can achieve the purpose; the patch features convenient use; in addition, the patch is flexible and appropriately adhesive.
Owner:SHENYANG PHARMA UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products