Formula of sugar-coated aerogenic powder, and preparation method of sugar-coated aerogenic powder

A gas-generating powder and sugar-coating technology, which can be used in pharmaceutical formulations, preparations for in vivo tests, and drug delivery, etc., can solve problems such as mental pain, patients' coughing, and affect the inspection effect, and achieve a pain-free and convenient operation. Effect

Inactive Publication Date: 2014-08-13
王琦
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the gas-generating agent used for examination is in the form of powder, it has a strong stimulating effect on the oral mucosa when it enters the patient's mouth. Patients generally suffer from coughing and choking, and even have difficulty swallowing, which brings unnecessary trouble and mental pain to the patients w

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0015] A formula of sugar-coated gas-generating powder of the present invention, the formula of sugar-coated gas-generating powder is made of the following raw materials: gas-generating powder and sugar coating, the parts by weight of the gas-generating powder are: 100 g of gas-generating powder, the sugar-coating Components and parts by weight ratio are: 35g starch, 15g sucrose, 2g tartrazine, 1g gum arabic, 1g methylcellulose, 5g talcum powder, 5g10% corn protein ethanol solution, 2g glycerin, 15g distilled water, 5g Sichuan wax powder;

[0016] The preparation method process of described sugar-coated gas-producing powder formula is as follows:

[0017] 1) extract 35g starch, 15g sucrose, 2g tartrazine, 1g gum arabic, 1g methylcellulose and 5g talcum powder according to the ratio of parts by weight and grind them into powder for later use;

[0018] 2) Extract 5g of 10% corn gluten ethanol solution and 2g of glycerol in 15g of distilled water according to the ratio by weight...

experiment example

[0023] Subjects: 8 patients who had just undergone barium meal angiography.

[0024] Experimental method and time: 8 patients first took the sugar-coated gas-producing powder formula of the present invention for barium meal radiography, recorded result 1, then took general gas-producing powder for barium meal radiography, recorded result 2, and compared the two results. Experimental results:

[0025] Remarks: Compared with result 1 and result 2, 5 people had tiny lesions that were not detected.

[0026]

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Patient 6

Patient 7

Patient 8

Taste (result 1)

it is good

better

it is good

it is good

it is good

it is good

it is good

better

Taste (result 2)

Difference

Difference

poor

poor

Difference

poor

generally

Difference

[0027] Afterwards, a physical survey was conducted on the patients in the exp...

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PUM

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Abstract

The invention discloses a formula of sugar-coated aerogenic powder, and a preparation method of the sugar-coated aerogenic powder. The formula of the sugar-coated aerogenic powder comprises 100g of aerogenic powder, and sugar coat, and the sugar coat comprises 35g of starch, 15g of sucrose, 2g of lemon yellow, 1g of Arabic gum, 1g of methyl cellulose, 5g of talcum powder, 5g of a 10% zein-ethanol solution, 2g of glycerin, 15g of distilled water and 5g of Chinese wax powder. The sugar-coated aerogenic powder has the advantages of simple preparation, use convenience, no irritation to the oral cavity, extremely easy digestion in human bodies, and no influences on the examination result, and can be easily accepted by patients especially child patients.

Description

technical field [0001] The invention relates to a formula of sugar-coated gas-producing powder and a preparation method thereof. Background technique [0002] At present, when the hospital performs the barium meal contrast examination of the digestive tract clinically, the gas-producing powder is generally used to meet the gas-barium double-contrast examination. The patient needs to pour a certain dose of the gas-producing powder directly into the mouth and drink it with water. After the body, the gastric organs are expanded to facilitate the examination of the instrument. Since the gas-generating agent used for examination is in the form of powder, it has a strong stimulating effect on the oral mucosa when it enters the patient's mouth. Patients generally suffer from coughing and choking, and even have difficulty swallowing, which brings unnecessary trouble and mental pain to the patients who seek medical treatment. , especially for some special patients with swallowing di...

Claims

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Application Information

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IPC IPC(8): A61K49/00A61K9/36
Inventor 王琦韩金花任振杰
Owner 王琦
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