System and method for separating and removing circulating tumor cell and blood platelet in blood

A technology for tumor cells and platelets, which is applied in the field of tumor cell separation and removal, can solve the problems of inability to achieve therapeutic effects, inability to remove tumor cells in cancer patients, and cumbersome operation steps, so as to avoid irreversible damage, prevent and spread metastasis, and improve separation flux effect

Active Publication Date: 2014-08-13
THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA
View PDF3 Cites 19 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, these methods generally have the disadvantages of low capture efficiency, cumbersome operation steps, low sensitivity, and easy irreversible damage to blood samples.
Due to the irreversible damage to the blood sample, the existing separation technology can only conduct preliminary analysis and detection of the blood, but cannot remove the tumor

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • System and method for separating and removing circulating tumor cell and blood platelet in blood
  • System and method for separating and removing circulating tumor cell and blood platelet in blood
  • System and method for separating and removing circulating tumor cell and blood platelet in blood

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0045] Example one:

[0046] This embodiment proposes a system for separating and removing circulating tumor cells and platelets in the blood, such as figure 1 As shown, the system includes a blood collection device 1, a first microfluidic separation unit 2 and a second microfluidic separation unit 3. The first microfluidic separation unit 2 includes four first microfluidic chips 21, and the second microfluidic separation unit 3 includes four second microfluidic chips 31. The inlet ends of the microchannels of the four first microfluidic chips 21 are all connected with the blood collection device 1. Such as figure 2 As shown, the outlet end of the microchannel of the first microfluidic chip 21 is divided into three branch outlets, which are a first branch outlet 211, a second branch outlet 212, and a third branch outlet 213 in the direction outward from the center of the chip. . The first branch outlets 211 of the four first microfluidic chips 21 are respectively connected to ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Diameteraaaaaaaaaa
Login to view more

Abstract

The invention discloses a system and method for separating and removing circulating tumor cell and blood platelet in blood, relates to the technical field of separation and removal of tumor cells, and aims at designing to solve the problems of poor effect on separating of circulating tumor cell, failure on blood platelet separation, failure on recycling of blood in the existing separating system. The system for separating and removing the circulating tumor cell and the blood platelet in the blood comprises a blood collecting device, a first micro-fluidic separating unit which is communicated with the blood collecting device through a pipeline, and a second micro-fluidic separating unit which is communicated with the first micro-fluidic separating unit through another pipeline; the first micro-fluidic separating unit is used for separating the circulating tumor cell in the blood; the second micro-fluidic separating unit is used for separating the blood platelet in the blood. The invention also provides a method for separating and removing the tumor cell and the blood platelet in the blood. With the adoption of the separating system, the circulating tumor cell and blood platelet in the blood of a patient with cancer can be effectively removed; the operation is simple and convenient; the separation effect is great; the spreading and metastasizing of cancer cells can be effectively controlled.

Description

technical field [0001] The invention relates to the technical field of tumor cell separation and removal, in particular to a system and method for separating and removing circulating tumor cells and platelets in blood. Background technique [0002] Cancer is one of the biggest killers that have seriously endangered human health in recent years, and the death rate it causes ranks among the top in every country in the world. With the development of medical technology, some progress has been made in the diagnosis and treatment of cancer, but most patients will experience recurrence and metastasis to varying degrees. Recent studies have shown that many factors affect the recurrence and metastasis of cancer, among which peripheral circulating tumor cells play a very important role. Circulating tumor cells are tumor cells that are shed from the primary tumor and invade the peripheral blood or lymphatic circulation. [0003] Since Ashworth first discovered tumor cells in the bloo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61M1/38
CPCA61M1/3621A61M1/38
Inventor 蒋兴宇逯文晶孙佳姝王纪东张璐
Owner THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap