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Ointment comprising lincomycin

A technology of lincomycin and ointment, which is applied in the field of ointment containing lincomycin, can solve the problem of no product, etc., and achieve the effect of easy carrying, convenient use and good stability

Inactive Publication Date: 2014-08-27
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there is no report on lincomycin ointment and its preparation process, and there is no related product

Method used

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  • Ointment comprising lincomycin
  • Ointment comprising lincomycin

Examples

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Embodiment 1

[0016] The invention provides a lincomycin ointment, which is made of the following ingredients:

[0017] Lincomycin 2.5g

[0018] The composition of glyceryl monostearate, lanolin and hexyl laurate (the weight ratio of the three is 2.7:4.1:1.5) 330g

[0019] The composition of polyethylene glycol 2000 and triethanolamine (the weight ratio of the two is 3:7) 150g

[0020] The composition of propylene glycol, oleic acid and lauryl methyl sulfoxide (the weight ratio of the three is 1.5:2.3:3.7) 115g

[0021] Sodium chloride 20g

[0022] Methylparaben 30g

[0023] Add distilled water to 1000g

[0024] The preparation method of lincomycin ointment, the steps are as follows:

[0025] (1) Glyceryl monostearate, lanolin and hexyl laurate in the above weight ratio of the prescription amount are mixed and heated to 70-80° C. to melt to make an oil phase;

[0026] (2) Under the condition of 70-80°C, the composition of prescription amount of lincomycin, polyethylene glycol 2000 and...

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PUM

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Abstract

The invention relates to an ointment comprising lincomycin. An ointment base material comprises an oily base material and a water-based base material, the oily base material is the composition of glycerin monostearate, lanolin and hexyl laurate, the weight ratio of the glycerin monostearate, the lanolin and the hexyl laurate is 2.7: 4.1: 1.5, the water-based base material is the composition of polyethylene glycol 2000 and triethanolamine, and the weight ratio of the polyethylene glycol 2000 and the triethanolamine is 3: 7.

Description

technical field [0001] The present application relates to an ointment, specifically, an ointment containing lincomycin. Background technique [0002] Lincomycin, the English name is Lincomycin. It acts on the 50S subunit of the ribosome of sensitive bacteria to prevent the elongation of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. Chemical name: 6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-6,8-dideoxy-D-erythro-α-D- Galactopyranoside hydrochloride monohydrate. Lincomycin is a white crystalline powder; it has a slight or special odor; it tastes bitter. Lincomycin is easily soluble in water or methanol and slightly soluble in ethanol. Lincomycin acts on the 50S subunit of the ribosome of susceptible bacteria to prevent the elongation of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. Lincomycin is generally a bacteriostatic agent, but at high concentrations, it also has a bactericidal effe...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K31/7056A61K47/14A61K47/34A61K47/10A61K47/12A61K47/20A61P31/04
Inventor 黄祥彬李志征周祎谢姗瑾
Owner XINXIANG MEDICAL UNIV
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