Epilepsy state closed-loop control experiment platform based on FPGA

An epileptic state and closed-loop control technology, applied in the field of biomedical engineering, can solve problems such as low precision, imperfect man-machine interface, and difficult analysis of FPGA hardware neuron network operation, so as to improve operability, flexibility, The effect of portable hardware experiment platform

Inactive Publication Date: 2014-10-22
TIANJIN UNIV
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Problems solved by technology

[0007] The existing technology is still in the basic stage, so there are still the following shortcomings: there is no special epilepsy control experiment platform based on FPGA with complete functions; the hardware simulation neuron network model

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  • Epilepsy state closed-loop control experiment platform based on FPGA
  • Epilepsy state closed-loop control experiment platform based on FPGA
  • Epilepsy state closed-loop control experiment platform based on FPGA

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[0021] The closed-loop control FPGA experimental platform structure of the epilepsy neural cluster network of the present invention will be described below in conjunction with the accompanying drawings.

[0022] The design idea of ​​the closed-loop control FPGA experimental platform of the epilepsy neural cluster network of the present invention is to first set up an epilepsy neural cluster network model with multiple neural clusters and complex coupling on the FPGA; then design PI type iterations independently of the neural cluster network model on the FPGA Learning controller, PI type iterative learning control signal is applied to the model as an external current stimulus, and the pathological discharge mode of the epileptic neural cluster network is changed through stimulation to make it produce normal discharge; finally, the software interface of the host computer is designed, and the software interface of the host computer is set by setting parameters And transmit it to t...

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Abstract

The invention provides an epilepsy state closed-loop control experiment platform based on an FPGA. The FPGA serves as a lower computer of the experiment platform, and discharging waveform observation and parameter setting are carried out with the help of an upper computer interface compiled through VB. An epilepsy nerve cluster mathematic model is achieved through the FPGA, discharge mode control of an epilepsy nerve cluster network is achieved by means of closed-loop feedback control, and an upper computer is used for conducting parameter adjustment and discharging waveform observation. The method has the advantages that modeling for a complicated epilepsy neuron network is achieved through the experiment platform serving as non-animal experimenting of a biological neural network and based on the high-speed calculation FPGA neuron network, and the time scale is consistent with that of real biological neurons. The visualization research platform more close to a real neural network is provided for researching a discharge mechanism of neuron clusters of the epileptic disease, epilepsy nerve cluster network closed-loop control under the action of an electric field and the like, and has great practical value for epileptic disease treatment research.

Description

technical field [0001] The invention relates to biomedical engineering technology, in particular to an FPGA experimental platform for closed-loop control of epilepsy based on a neural cluster model. Background technique [0002] Epilepsy is a neurological disease caused by temporary central nervous system dysfunction due to abnormal synchronous excessive discharge of brain cells. So far, there is no thorough and effective treatment. This motivates us to explore new treatments for epilepsy. A large number of studies have shown that seizure transmission originates from or passes through the hippocampus, which is an important region for the generation and seizure of neurological diseases. Because electrical stimulation has the characteristics of flexibility, reversibility and less invasion compared with clinical surgery for epilepsy, it has become an important method to eliminate epileptic seizures. Researchers use different electric field stimulation experiments to weaken or...

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Application Information

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IPC IPC(8): G06F19/00
Inventor 王江杨双鸣邓斌魏熙乐于海涛张茂华
Owner TIANJIN UNIV
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