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Anti-infectious callicarpa bodinieri injection and preparation method thereof

A kind of technology of Zizhucao and injection, applied in the direction of resisting media-borne diseases, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problem of unsatisfactory anti-infection effect, achieve low cost of medicinal materials, and Easy to get the source and reduce the economic burden

Inactive Publication Date: 2014-10-29
付丽娜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it can be seen from other experiments that its anti-infective effect is not satisfactory.

Method used

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  • Anti-infectious callicarpa bodinieri injection and preparation method thereof
  • Anti-infectious callicarpa bodinieri injection and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 The preparation steps of the anti-infective Zizhucao injection are as follows:

[0033] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 2 hours each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, and discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0034] (2) Take the crude dry powder obtained in step (1), dissolve it with a small amount of water for injection, add lead acetate, stir well, put it in the refrigerator overnight, separate and precipitate to obtain a light yellow solution, add 50% sulfuric acid dropwise to adjust pH 1 to remove lead, filter To obtain a light yellow solution, add 2N sodium carbonate dropwise to bring the pH to 6.5, add 5 times the amount of 65% ethanol to precipitate out, discard the mother liquor, and dry below 60°C;

[0035] (3) Put the chrysanthem...

Embodiment 2

[0038] Example 2 The preparation steps of the anti-infective Zizhucao injection are as follows:

[0039] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0040] (2) Take the crude dry powder obtained in step (1), dissolve it with a small amount of water for injection, add lead acetate, stir well, put it in the refrigerator overnight, separate and precipitate to obtain a light yellow solution, add 50% sulfuric acid dropwise to adjust pH 2 to remove lead, filter To obtain a light yellow solution, add 2N sodium carbonate dropwise to bring the pH to 6.5, add 5 times the amount of 65% ethanol to precipitate out, discard the mother liquor, and dry below 60°C;

[0041] (3) Put the chrysanthemum i...

Embodiment 3

[0046] Example 3 The preparation steps of the anti-infective Zizhucao injection are as follows:

[0047] (1) Take the coarse powder of Zizhucao, extract it twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on the distribution funnel, discard the ethanol Mother liquor, precipitation, and drying below 60°C to obtain dry powder of crude water extract;

[0048] (2) Take the crude dry powder obtained in step (1), dissolve it with a small amount of water for injection, add lead acetate, stir well, put it in the refrigerator overnight, separate and precipitate to obtain a light yellow solution, add 50% sulfuric acid dropwise to adjust pH 1 to remove lead, filter To obtain a light yellow solution, add 2N sodium carbonate dropwise to bring the pH to 6.5, add 5 times the amount of 65% ethanol to precipitate out, discard the mother liquor, and dry below 60°C;

[0049] (3) Put the chrysanthemum i...

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Abstract

The invention discloses an anti-infectious callicarpa bodinieri injection and a preparation method thereof. Every 100ml of the callicarpa bodinieri injection comprises the following main ingredients: 10-20g of callicarpa bodinieri aqueous extract and 6-9g of loosestrife aqueous extract. The injection can be used for treating pharyngalgia, headache, thirst, enteritis and dysentery, upper respiratory infection, septicemia and other bacterial or virus infections and wound infection caused by bacteria or viruses, and has the effects of clearing heat and resisting inflammation, purging internal fire and removing toxicity, clearing heat and drying dampness, inhibiting bacteria and resisting viruses.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an anti-infection Zizhucao injection and a preparation method thereof. Background technique [0002] Infection is the deleterious replication, reproduction process by another species in an individual as a host. Infectious organisms will look for and use the host's internal resources for their own survival, but once this process interferes with the normal physiological operations of the host, it may cause chronic symptoms, acute symptoms, gangrene, engulfment of organs and tissues, and even death. Such species are also called pathogens, usually microorganisms, but in fact infections can be defined more broadly, including bacteria, viruses, parasites, fungi, viroids, or even infectious substances that have the ability to cause disease, but are not biological, For example poon protein. [0003] Infection can cause tissue damage, leading to different clinical phenomena....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/08A61P31/04A61P31/12A61K36/185
CPCY02A50/30
Inventor 付丽娜
Owner 付丽娜
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