Preparation method for amine-group-rich polymerization film

Abstract

A disclosed preparation method for an amine-group polymerization film is characterized by comprising performing copolymerization on an organic amine compound with amine groups at two ends and a polyphenol compound containing catechol, and regulating the reaction conditions, so as to obtain the film rich in amine functional groups on the surface of a basic material. The prepared polymerization film has relatively high surface amine content, and is applicable to fixation of a plurality of biological molecules. The prepared film is good in stability, the catechol compound has extremely strong binding force with the base material, and also introduction of the organic amine compound helps to improve the crosslinking degree of the film and further enhancing the stability of the film. The preparation method is simple and practicable, can used to perform deposition on surfaces of a plurality of materials, does not need complex equipment, is low in technological cost, and establishes a base for applying the film to surface modification of biological materials.

Description

technical field [0001] The invention relates to a method for preparing a polymeric film with abundant amino functional groups, which is applied to the surface modification of biological materials. Background technique [0002] Surface modification of biomaterials is a technology that improves the surface properties of materials or enhances special surface properties without affecting the properties of the material itself. It plays an irreplaceable role in the fields of chemistry, biology, materials science, and applied science, engineering, and technology. effect. Existing methods for functional modification of material surfaces include self-assembled thin films, silanization, physical / chemical vapor deposition, and surface grafting. Although these methods are commonly used in research, many methods have many limitations in wide application. For example, the requirements for interface modification and chemical specificity between surfaces, complex equipment used, requiremen...

AI Technical Summary

Problems solved by technology

However, the secondary reactivity of the dopamine film is limited to biomolecules with sulfhydryl or amine groups, because the secondary reactivity of the dopamine film is based on the combination of the phenolic hydroxyl or quinone groups retained on the dopamine film with the biomolecules. Amino or sulfhydryl based on Michael addition or Schiff base reaction

However, there is no report on the introduction of hexamethylenediamine and dopamine copolymerization to prepare films.