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A kind of external medicine for treating ringworm and preparation method thereof

A technology of ointment and mixture, which is applied in the direction of medical formula, drug combination, drug delivery, etc. It can solve the problems of unreported and unsatisfactory effects, and achieve the effect of obvious healing effect, low toxicity and side effects, and 100% effective rate

Active Publication Date: 2017-04-05
GUIZHOU TELIDA NANO CARBON SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this medicament can achieve a certain effect for the treatment of ringworm, and can also kill the ringworm to a large extent, and control the spread and recurrence of the ringworm, its effect is also relatively unsatisfactory.
[0004] Carbon powder has strong adsorption performance, can completely absorb colored and harmful substances in water, and then achieve the purpose of purification; at the same time, there are certain reports on the technical literature of carbon powder as a tracer in the medical field, and it is used as a carrier , the drug for treating a certain disease is delivered to the patient part, and the drug is attached to the diseased part through strong adsorption properties, so as to achieve the purpose of treatment. However, there is no report on the technical literature of using carbon powder to treat patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A kind of preparation method of the medicine for external use for the treatment of tinea is that the particle size containing 95% is 5nm, and the dispersibility in water is 99.35% nano-carbon powder is dissolved in the solution solvent together with the dispersant, after stirring for 40min, Then it was subjected to ultrasonic treatment for 3.5h, after it was fully dispersed, after adding pharmaceutical auxiliary materials, and using a stirring speed of 45r / min to stir for 15min, after the stirring was completed, sodium bicarbonate-sodium carbonate buffer solution was added to it to adjust When the pH value of the solution is 7.3, it is placed in a temperature of 70° C., and when it is concentrated to one-third, the external medicine for treating ringworm is obtained.

[0024] Among them, the mass percentage of nano-carbon powder is 1.5%, the mass percentage of dispersant is 21.3%, the mass percentage of solution solvent is 70.2%, and the rest are pharmaceutical auxiliary...

Embodiment 2

[0029] A preparation method of an external drug for treating ringworm, comprising dissolving nano-carbon powder containing 97% of the particle size of 1.1nm and having a dispersibility of 99.35% in water with a dispersant in a solution solvent, and stirring for 20 minutes , then ultrasonically treat it for 1.1h, after it is fully dispersed, add vaseline, and use a stirring speed of 30r / min to stir for 10min, after the stirring is completed, add sodium bicarbonate-sodium carbonate buffer solution to adjust the solution When the pH value is 5.8, it is placed in a temperature of 50°C, and when it is concentrated to one-third, the external medicine for treating ringworm is obtained.

[0030] Wherein, the mass percentage of nano-carbon powder is 0.3%, the mass percentage of dispersant is 13.5%, the mass percentage of solution solvent is 83.2%, and the rest is petroleum jelly.

[0031] Moreover, the dispersant is prepared by mixing sodium lignosulfonate, triethylhexylphosphoric acid...

Embodiment 3

[0035] A kind of preparation method of the medicine for external use for the treatment of tinea is that the particle size containing 98% is 3nm, and the dispersibility in water is 99.35% nano-carbon powder is dissolved in the solution solvent together with the dispersant, after stirring for 30min, Then ultrasonically treat it for 2 hours, after it is fully dispersed, add pharmaceutical excipients, and stir at a stirring speed of 40r / min for 10-15min, after the stirring is completed, add sodium bicarbonate-sodium carbonate buffer solution When the pH value of the solution is adjusted to 6.8, it is placed in a temperature of 60° C., and when it is concentrated to one-third, the external medicine for treating ringworm is obtained.

[0036] Among them, the mass percentage of nano-carbon powder is 1.1%, the mass percentage of dispersant is 19.8%, the mass percentage of solution solvent is 73.7%, and the rest are pharmaceutical auxiliary materials.

[0037] The pharmaceutical auxili...

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Abstract

The invention relates to the technical field of medicines for treating skin infections, in particular to a medicine for external use for treating ringworm and a preparation method thereof, which contains ≥95% of nano-carbon powder with a particle size of 1.1-5nm and a dispersibility of 99.35% in water and Mix the dispersant and the solution solvent, and stir for 20-40min, then place it in ultrasonic treatment for 1.1-3.5h, so that the nano-carbon powder can be fully dispersed evenly, and then by adding pharmaceutical excipients (Vaseline), After being concentrated and made into an ointment, the efficacy of the prepared external medicine for treating ringworm is greatly improved, so that the cure rate of the medicine for ringworm reaches more than 99%, and the effective rate is 100%.

Description

technical field [0001] The invention relates to the technical field of drugs for treating skin infections, in particular to an external drug for treating ringworm and a preparation method thereof. Background technique [0002] The kind of tinea mainly comprises tinea capitis, tinea corporis, jock itch, tinea manuum, tinea pedis, tinea unguium, tinea versicolor, and tinea fungus eruption according to the pathological features that grow in different parts of the human body and tinea. One of the most important features of ringworm is stubborn growth. Once infected, it is difficult to cure it, and its infectivity is strong, and the diseased part expands quickly. [0003] The treatment and prevention methods for ringworm are the same as other infectious diseases, that is, to eliminate the source of infection, cut off the route of transmission and protect the susceptible parts; however, this method can only hinder the further expansion of ringworm, thereby reducing the incidence ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/44A61K9/06A61P31/10A61P17/00
CPCA61K9/0014A61K9/06A61K33/44
Inventor 聂瑛洁李力
Owner GUIZHOU TELIDA NANO CARBON SCI & TECH