123 results about "Tinea imbricata" patented technology

Dermatophytes which belong to one of the three genera Epidermophyton, Trichophyton and Microsporum are the main cause of fungal infections of skin, hair and nails. Traditional diagnostic procedures consist of microscopy and culture, but due to the slow growth rate of dermatophytes typically two to four weeks are needed before a final diagnosis is obtained. The present invention is a rapid DNA extraction method extracting nucleic acids from fungi (e.g. dermatophytes and other pathogenic fungi) which can be performed from directly on hair, nail or skin specimens from humans, from naturally or experimentally infected animals or from cultured fungal colonies for the use in PCR amplification and detection assays. The present invention also includes specific primer sets for detection of any dermatophyte and for species specific detection of Trichophyton rubrum and Epidermophyton floccosum by PCR and a kit for diagnosing fungal infections.

The present invention belongs to the field of traditional Chinese medicine, in particular to a Chinese medicine which is used for treating cough and asthma, and a preparation method thereof. The Chinese medicine is prepared from the following medicinal materials: reed rhizome, seed of fructus trichosanthis, seed of Chinese waxgourd, coix lacryma-jabi, honeysuckle, cordate houttuynia, root of straight ladybell, fructus schizandrae, densely baked almond, gingko-nut, densely baked licorice, densely baked Donghua (winter blooming), densely baked aster, molten exocarpium citri rubrum, balloon-flower root, peach kernel, fried areca, fructus aurantii immaturus, magnolia obavata, medicated leaven, fried corium stomachichum galli, barrenwort, desertliving cistanche and herba pyrrosiae. Based on the conventional treatment, the Chinese medicine avoids the traditional method which can not treat internal asthma and external tinea when treating lung in the sick period and the kidney in everyday life. Moreover, the Chinese medicine has the advantages of reasonable formula, precise and rapid curative effects, and mild use, and is suitable for treating a plurality of types of cough and asthma, fundamentally the cough and asthma.

The invention relates to an externally used traditional Chinese medicament for treating skin diseases which is prepared mainly from the following raw materials (by weight portion): cnidium fruit 0. 5-2 parts, roor of sessile stemona 0. 5-2 parts, Cortex Pseudolaricis 0. 5-2 parts, kuh-seng 0. 5-2 parts, sea apron 0. 3-1 part, seaweed 0. 3-1 part, oldenlandia 0. 5-2 parts, rheum officinale 0. 5-2 parts, rheum officinale 0. 2-0. 8 part, Chinese blistering beetle 0. 1-0. 5 part, edible vinegar concentrate 45-55 parts, arisaema tuber 18-25 parts and secretio bufonis 3-5 parts.

The subject matter relates to a topical, foamable composition including at least one antifungal agent, said composition characterised in that said at least one antifungal agent is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and in that it has a residual non-volatile component content of less than 25%. The subject matter furthermore relates to a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis by applying to the affected area of a patient requiring such treatment the antifungal composition.

A ring-shaped toe-patch is provided for treatment and prevention of tinea pedis, commonly known as athlete's foot. The toe-patches are made of rubber-foam, attached to a hydrophobic material for elimination of fungus like T. rubrum. The toe-patch has cuts extending into the patch from the central circle in the toe-patch. Due to its perfect fit the toe-patch comes close to the affected area making it possible for a hydrophobic material attached to foam to effectively bind the fungi. Simultaneously with the elimination of the fungi the toe-patch works as a toe separator creating space between the toes.

The invention discloses a Shanhu Xuanjing spray and a preparation method thereof. The Shanhu Xuanjing spray is prepared from roots of zingiber corallinum hance, radix curcumae longae, borneol, salicylic acid, glycerol, acetic acid and auxiliary materials including liquid carbon dioxide and sodium hydrogen pyrosulfite, and can efficiently regulate vital energy and blood balance at the soles of the feet and kill the fungi. Compared with the medicine in the conventional dosage form, the spray has better permeation effect, can dissolve the skin cutin, can play the treatment effect of the medicine better, and is more convenient to use.

The invention relates to a traditional Chinese herbal medicine for treating tinea and a preparation method thereof. The traditional Chinese herbal medicine mainly comprises the following components in parts by weight: 360-450 parts of sophora flavescens, 450-520 parts of poria, 500-580 parts of cortex phellodendri, 480-570 parts of dictamnus dasycarpus turcz, and 350-430 parts of broom cypress fruit. The preparation method is as follows: adding the crops into the traditional Chinese herbs, and fermenting and distilling to form liquid traditional Chinese herbal medicine for treating tinea which can be stored for a long time. The traditional Chinese herbal medicine for treating tinea has the characteristics of remarkable treatment effect and scientific and reasonable preparation method, and has the advantages of fundamentally treating tinea and being less in side effect.

The invention discloses a tinea washing traditional Chinese medicinal preparation and a preparation method thereof. The tinea washing traditional Chinese medicinal preparation is prepared from the following raw materials in part by weight: 8 to 12 parts of common yam rhizome, 14 to 16 parts of pseudolarix, 18 to 22 parts of edible tulip, 14 to 16 parts of pepper, 28 to 32 parts of barbados aloe, 28 to 32 parts of purslane, 14 to 16 parts of mint, 14 to 16 parts of Saposhnikovia divaricata, 28 to 32 parts of lithospermum, 8 to 12 parts of aluminite, 28 to 32 parts of Sophora flavescens, 28 to 32 parts of cortex dictamni, and 18 to 22 parts of common cnidium fruit. The formula raw material are crushed and uniformly mixed, and the mixture is sterilized at a high temperature and packaged by bags. The pure traditional Chinese medicinal powder has the effects of clearing heat and detoxifying, is mainly used for treating various kinds of tinea and can produce remarkable and quick effect.

The invention discloses an external pharmaceutical composition used for treating skin diseases like eczema, dermatitis and tinea and a preparation method thereof. The pharmaceutical composition comprises, by weight, 10 to 100 parts of amur cork-tree bark, 5 to 60 parts of coptis, 5 to 60 parts of natural indigo, 3 to 60 parts of calamine, 3 to 60 parts of dried alum, 1 to 80 parts of artificial cow-bezoar, 2 to 20 parts of borneol and 0.5 to 10 parts of muschus. The invention further discloses a preparation method for an ointment, a gel, a lotion and a cream of the external pharmaceutical composition. The external pharmaceutical composition has a reasonable formula, exerts the effects of heat clearing, detoxifying, dampness eliminating, itching relieving, necrotic tissue removing and tissue regeneration promoting and is applicable to treatment of the skin diseases like eczema, dermatitis and tinea. The preparation method is simple, easy to operate and suitable for industrial production.

The invention provides a partially externally used relieve itching epithem and its preparation process, wherein the epithem employs garlic as the principal active composition, the preparation comprises selecting fresh ripened garlic bulb or haulm or scape and disintegrating, charging different solvent, steeping or mixing, extracting 0.5-12 hours at 20-90 deg. C, stewing 10-20 hours at 4-25 deg. C, decompressing and concentrating, and mixing the extract and right amount of medicinal adjuvant.

The invention relates to a Chinese medicine preparation for treating tinea and its preparation process, wherein the preparation comprises flavescent sophora root, white alum, cnidium fruit, Schizonepeta tenuifolia, ledebouriella root, Chinese dittany bark, safflower, cortex acanthopanacis, Chinese honey locust and vinegar.

The invention discloses a medicine for dispelling tinea, wherein the formulation of the medicament includes Chinese angelica root 10-15g, dittany bark 15-20g, flavescent sophora root 15-20g, spatholobus stem 20-30g, barbat skullcap 15-20g, buthus martensi kirsch 6-10g, cattail pollen 40-50g, natural indigo 40-50g, clove 50-60g, radix euphorbiae ebracteolatae 6-10g, rhubarb 10-15g.

The invention relates to a Chinese medicinal composition for treating tinea, wherein the constituents include gen-seng, astragalus root, pilose asiabell root, rhizoma dioscoreae, poria cocos, prepared rhizome of rehmannia, matrimony vine, pulp of dogwood fruit, dipsacus root, root of red rooted saliva, peach kernels, motherwort, boneol, centipede, flavescent sophora root, natural indigo, corktree bark, goldthread root, beach silvertop root, wild chrysanthemum flower and arctium fruit,

The invention provides a Chinese traditional patent medicine used for treating tinea through external administration, belonging to the technical field of the Chinese traditional patent medicine. The invention aims at solving the problems of poor curative effect and frequent relapse in the existing medicines used for treating tinea. The invention has following components by weight proportion: 26-34 parts of cantharis, 180-220 parts of Sichuan hot pepper, 20-36 parts of centipede, 260-330 parts of cortex pseudolaricis, 260-342 parts of camphor, 350-430 parts of white alum, 380-412 parts of realgar and 140-158 parts of common cnidium fruit; 5000-10000 parts of liquor is adopted for soaking according to the weight proportion so as to refine the Chinese traditional patent medicine used for treating tinea through external administration. The invention has reasonable prescription, significant curative effect, can treat both manifestation and root cause, and is suitable for the treatment of moist tetter, psoriasis, scald head, tinea manuum, tinea pedis, erythrasma and tinea circinata, etc. tinea.

The invention provides application of an evodiamine derivative in preparation of a medicine for treating superficial fungal infection. The evodiamine derivative disclosed by the invention is prepared by taking a methyl anthranilate compound and tryptamine as initial raw materials through amine-ester exchange and a one-step ring closing reaction catalyzed by Lewis acid. The evodiamine derivative disclosed by the invention can show good antibacterial activity on three fungi, namely trichophyton rubrum, trichophyton mentagrophytes and candida albicans. Moreover, cell walls, cell membranes and organelles of fungal spores are destroyed to a certain extent, the hydrophobicity of fungal biomembranes can be influenced to a certain extent, phenomena of dark red erythema, skin hardening and generation of a large amount of scurf caused by errhysis spots of skin subjected to dermabrasion treatment can be obviously relieved, and phenomena of thickened epidermal layer of skin tissue, small-area epidermal layer necrosis, cuticle small-area parakeratosis and the like are avoided. The evodiamine derivative has low toxicity and low drug resistance and can be applied to preparation of drugs for treating the superficial fungal infection.

An exterior-applied ointment for treating skin tinea is prepared from white vaseline, stearic acid, glycerine, nipagin, atoleine and 6 Chinese-medicinal materials including dittany bark, cnidium fruit, broom cypress fruit, etc. Its advantages are high curative effect and no odor.

A ringworm vaccine is disclosed comprising antigen isolated from at least one dermatophyte and a suitable carrier. The “antigen” can include a single antigen from a dermatophyte or a plurality of antigens as long as at least one antigen is included which will produce a sufficient immune response to confer resistance to ringworm infection upon the recipient of the vaccine. The antigen can also be isolated from more than one dermatophyte. If a preparation from more than one dermatophyte is made the antigen can include antigens which are common to all species of dermatophytes employed and / or antigens which are only specific to certain species. A method of producing such a ringworm vaccine is also disclosed.

The invention discloses a tinea-resistant deodorizing nourishing and health care fragrant shoe, comprising the following raw materials by weight percent: 30-50% of adhesives, 15-42% of nourishing agent, 20-47% of bactericidal agent and 1.2-2.3% of flavoring agent. The tinea-resistant deodorizing nourishing health care fragrant shoe further comprises the following components by weight percent: 8% of royal jelly powders and 5% of aloe glue powders, wherein the adhesive is Bali adhesive, the nourishing agent is aloe mineral crystal, the bactericidal gent is triclosan, and the flavoring agent is lemon flavors and osmanthus fragrans flavors. The ringworm-resistant deodorizing nourishing health care fragrant shoe can lastingly remove such pedopathy as tinea pedis, foot stink, onychomycosis and the like, and has substantial effect without relapse.

A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component content of less than 25%. In addition, a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis is provided, and includes applying to the affected area of a patient requiring such treatment an antifungal composition.

The invention relates to a Chinese medicinal sterilizing liquor for treating skin tinea and eczema, which is a preparation prepared from the following raw materials by weight: 15 to 20kg of cortex dictamni, 5 to 10kg of pseudolarix kaempferi gord, 8 to 15kg of smilax glabra roxb, 10 to 15kg of sanguisorba officinalis L.and 50 to 70kg of 60 percent white spirit. The Chinese medicinal sterilizing liquor for treating the skin tinea and the eczema is prepared by slicing the cortex dictamni, the pseudolarix kaempferi gord, the smilax glabra roxb and the sanguisorba officinalis L.; soaking the slices in the 60 percent white spirit. The Chinese medicinal sterilizing liquor is an external preparation, greatly reduces adverse reaction, is directly used for infected parts to accelerate absorption, and makes patients out of skin diseases as soon as possible. The Chinese medicinal sterilizing liquor is different from the conventional Chinese medicinal herb compound preparation. Experiments and tests prove that the product has the advantages of no toxic or side effects, short treatment course, quick response, obvious effect, relapse prevention, economy, simpleness and convenience. Compared with oral medicaments and external methods for clinically treating skin diseases caused by dermatophyte, the Chinese medicinal sterilizing liquor has essential difference and fundamentally relieves pains.

The invention relates to a plaster used for curing various dermatosis, which is a miracle plaster to treat skin diseases such as ichthyosis, psoriasis, and various ringworm, etc. and a preparation method thereof. The plaster is a combination of Traditional Chinese Medicine and western medicine, wherein, the components of Chinese Medicine are that (by weight percentage): 15-25 percent of pseudolarix, 15-25 percent of fructus cnidii, and 5-15 percent of dictamni cortex; while the components of western medicine are that (also by weight percentage): 15-25 percent of neomycin sulfate cream, 15-25 percent of urea cream and 15-25 percent of clotrimazole cream. The preparation method is that: the pseudolarix, the fructus cnidii and the dictamni cortex are weighed according to the weight percentage, mixed and soaked in water for 1-2h, and oiled by bloom fire and cooked for 1-2h by mild fire, and then the medicated liquor is poured out and filtered and dehydrated by mild fire to obtain thick liquid; next, the neomycin sulfate cream, the urea cream and the clotrimazole cream are mixed and well stirred to form a mixed cream; finally, the thick liquid and the mixed cream are mixed in a proportion of 1:1 (by weight) and then well stirred to get the finished product. The plaster is characterized by simple preparation method, easily obtained raw materials, low cost and easy production.

The invention discloses a folium artemisiae argyi extract and a preparation method and application thereof to dermatophyte antibacterial agents, and belongs to the field of technical application of plant source antibacterial agents. The antibacterial agents are folium artemisiae argyi extracts prepared by taking traditional Chinese medicinal materials of folium artemisiae argyi as raw materials through ultrasonic extraction (5-75% ethanol) or ethanol reflux extraction, and have an efficient inhibition effect on dermatophytes such as trichophyton rubrum, trichophyton mentagrophytes and microsporum gypseum. After the folium artemisiae argyi extracts are separated and purified through macroporous adsorption resin, 40-95% ethanol separation components have different degrees of inhibition activity on the dermatophytes, wherein the 95% ethanol separation components are most significant. Meanwhile, the main chemical components in the 95% ethanol separation components are eupatilin, physcion, vitexin, brown cyanidin and the like. The folium artemisiae argyi extract can efficiently inhibit the dermatophytes, has the advantages of safety, high efficiency and low toxic and side effects, and provides a new drug source for prevention and treatment of dermatophyte diseases such as tinea of feet and hands.

The invention discloses a medicine for dispelling tinea, wherein the formulation of the medicament includes Chinese angelica root 10-15g, dittany bark 15-20g, flavescent sophora root 15-20g, spatholobus stem 20-30g, barbat skullcap 15-20g, buthus martensi kirsch 6-10g, cattail pollen 40-50g, natural indigo 40-50g, clove 50-60g, radix euphorbiae ebracteolatae 6-10g, rhubarb 10-15g.

The invention discloses a jiumiao jiaxianling traditional Chinese medicine composition which is prepared from the following components in parts by weight: 1-30 parts of golden larch bark, 1-30 parts of common goldenrod, 1-30 parts of fructus cnidii, 1-30 parts of dragon blood, 1-30 parts of rheum officinale, 1-30 parts of golden cypress, 1-15 parts of indigo naturalis, 1-15 parts of dried alum and medical oil, including 0.1g-3 parts of artemisia scoparia oil, 0.1g-3 parts of clove oil, 0.1g-3 parts of zanthoxylum oil and 0.1g-3 parts of artemisia oil. The traditional Chinese medicine composition has the killing effect on dermatophytes, trichophyton rubrum, trichophyton gypseum, epidermophyton floccosum, alpha fungus, molds, saccharomycetes and the like and has the advantages that a patient feel less pain, the effect is good, the disease is not easy to relapse, the bacteria can be thoroughly killed, and the small toxic or side effect is caused.

The blood cleaning metabolism bolus of the present invention is used for treating hemopathy and hemopathy related hyperlipemia, cardiac and cerebral angiosclerosis, psoriasis, hypertension, etc. It is prepared with Chinese medicinal materials including rehmannia root, red peony root, peony bark, etc. and through washing, stoving, crushing, grinding into fine powder, mixing with honey and making bolus. It has functions of stopping bleeding, dissolving thrombus, promoting blood circulation, etc. and has obvious curative effect, low cost and no toxic side effect.

The compound phellodendron liniment for curing tinea is made of six Chinese medicinal materials of xanthium fruit, flavescent sophora root, phelldendron bark, cnidium seed, alum and clutch through the processes of soaking, decocting, precipitation, filtering, concentrating, taking out supernatant fluid and mixing it with vinegar. For curing tinea manuum and tinea pedis its cure rate is above 80%,and its total effective rate is above 90% and for curing tinea corporis and tinea cruris its cure rate is above 90% and its total effective rate is 100%.

The invention discloses compound nano-silver emulsifiable paste and a preparation method thereof. The compound nano-silver emulsifiable paste is O / W or W / O type emulsifiable paste prepared from nano-silver and zinc oxide as main drugs by certain processes. Nano-silver has strong antibacterial effects and a wide antimicrobial spectrum and causes drug resistance of bacteria difficultly. Zinc oxide has convergence and wound heal promotion effects. The compound nano-silver emulsifiable paste prepared from nano-silver and zinc oxide has anti-infection and wound heal promotion effects. The compound nano-silver emulsifiable paste has treatment advantages of moisture exposed burn ointment and sulfadiazine silver cream and avoids treatment defects and adverse reactions of moisture exposed burn ointment and sulfadiazine silver cream. The compound nano-silver emulsifiable paste can be used for anti-infection treatment on burns and scalds, infected wounds caused by physical mechanical damages, and chronic surface ulcers, and promotion of wound heal. The compound nano-silver emulsifiable paste can also be used for treatment on skin diseases such as sores, carbuncles, furuncles, erysipelas and tinea caused by bacteria, fungi and viruses.

A ringworm vaccine is disclosed comprising antigen isolated from at least one dermatophyte and a suitable carrier. The “antigen” can include a single antigen from a dermatophyte or a plurality of antigens as long as at least one antigen is included which will produce a sufficient immune response to confer resistance to ringworm infection upon the recipient of the vaccine. The antigen can also be isolated from more than one dermatophyte. If a preparation from more than one dermatophyte is made the antigen can include antigens which are common to all species of dermatophytes employed and / or antigens which are only specific to certain species. A method of producing such a ringworm vaccine is also disclosed. The method comprises making an antigen preparation comprising the dermatophyte antigen described above and combining the antigen preparation with a suitable carrier. Methods of treating a patient are also disclosed employing the vaccine of the present invention and vaccines produced according to the method of the present invention. Methods are also disclosed for treating a pregnant with such vaccines such that the progeny of the pregnancy exhibit resistance to ringworm infection at birth.

The present invention relates to a liquid medicine in treating tinea, ringworm and dermatomycosis and its preparation method. It is prepared by the following steps: using the Chinese medicinal materials of clove, stemona root, alum and sumac gallnut as raw material, proportioning them, soaking them in alcohol for several days, adding edible vinegar essence so as to obtain the invented product. Said liquid medicine not only can be used in effectively treating tinea corporis, tinea manuum and tinea pedis, but also can be used in treating general dermatosises of eczema, red swelling and titillation, and its therapeutic effect is obvious.