Metal ruthenium porphyrin, and preparation method and application thereof

Abstract

The invention relates to a metal ruthenium porphyrin, and a preparation method and application thereof. The chemical structural formula of the metal ruthenium porphyrin is disclosed in the specification. The invention also relates to a preparation method of the metal ruthenium porphyrin and application of the metal ruthenium porphyrin in preparing a metalloporphyrin framework compound using ruthenium as a node. The preparation method has the characteristics of high yield, low cost, short reaction time and environment friendliness; and the prepared product has no toxicant residue.

Description

technical field [0001] The present invention relates to a metal porphyrin and its preparation method and application, in particular to a metal ruthenium porphyrin and its preparation method and application. Background technique [0002] Metalloporphyrins are biological models of proteins such as catalase, peroxidase and cytochrome P-450, and are an important class of biomimetic catalysts with good thermal and chemical stability; at the same time, Metalloporphyrin ligands with catalytic properties are important functional blocks of metal-organic frameworks (MOFs), which make the metal-organic frameworks (MOFs) functional and more stable. The excellent properties of metalloporphyrins and their derivatives make them show attractive application prospects in biomimetic systems, molecular recognition, catalysis, materials, organic synthesis and medical treatment. [0003] Metalloporphyrins are formed by the combination of free porphyrins and metal ions. They not only have the cha...

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Problems solved by technology

[0004] At present, the most commonly used method for synthesizing metalloporphyrins is the N,N-dimethylformamide (DMF) method: metal salts and porphyrins are refluxed in DMF for 12 hours, after the reaction, the DMF is evaporated and a large amount of water is added to wash away excess metal Salt can be used to obtain metalloporphyrins, but it needs to be heated and refluxed under the protection of inert gas, the equipment is complex and the cost is high

For example, the prior art CN200610124361.2 discloses a ruthenium porphyrin complex and its preparation method and its application as a photosensitizer for photodynamic therapy, wherein cis-Ru(L)2Cl2 is synthesized in the preparation method step (1): Put RuCl3, bipyridine or bipyridine analogs, and lithium chloride in a three-necked flask, add DMF, heat to reflux under argon protection, cool to room temperature, add acetone, and freeze overnight; filter with suction, use ice water for precipitation, and cool Wash several times with acetone and dry in vacuum to obtain cis-Ru(L)2Cl2 crystals; it needs the protection of argon gas, takes a long time, has high cost, and contains anionic ligands, and there will be toxic residues in the ruthenium porphyrin made

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