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Chinese patent medicine tablets for treating cardiovascular and cerebrovascular diseases and preparation method of Chinese patent medicine tablets

A technology of cardiovascular and cerebrovascular diseases and Chinese patent medicines, which is applied in the field of preparation of plant extract pharmaceutical dosage forms, can solve the problems of singleness and insignificant effect, achieve the effect of auxiliary treatment, improve cardiovascular and cerebrovascular diseases, and make up for the limitations

Inactive Publication Date: 2015-01-14
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Driven by modern drug release technology and various dosage forms, ginkgo biloba preparations have become one of the most popular varieties in the plant market, but at present, most of them are in the form of injection or oral liquid. The effect of other drug compatibility is not significant

Method used

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  • Chinese patent medicine tablets for treating cardiovascular and cerebrovascular diseases and preparation method of Chinese patent medicine tablets
  • Chinese patent medicine tablets for treating cardiovascular and cerebrovascular diseases and preparation method of Chinese patent medicine tablets
  • Chinese patent medicine tablets for treating cardiovascular and cerebrovascular diseases and preparation method of Chinese patent medicine tablets

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Effect test

Embodiment 1

[0029] A Chinese patent medicine tablet for treating cardiovascular and cerebrovascular diseases, the main components and auxiliary materials are:

[0030] 20g Ginkgo biloba extract, 10g Polygonum multiflorum extract, 10g Uncaria extract, 40g carrier PVP-K30, 40g soluble starch, 20g magnesium stearate.

[0031] Ginkgo biloba extract, Polygonum multiflorum extract, and Uncaria extract are crushed and powdered, passed through a 100-mesh sieve, and the remaining materials are respectively passed through a 100-mesh sieve; the three drugs, carriers and soluble starch are mixed evenly in proportion, and an appropriate amount of water is added. Make it into a sticky paste; dry it in an electric constant temperature drying oven, set the temperature at 70°C, and crush it with a pulverizer after the drug is dry, and pass it through a 100-mesh sieve; set the tablet pressing pressure of the tablet machine to 10KN, and the filling depth to 12mm. The thickness of the dose is 4mm; magnesium ...

Embodiment 2

[0033] A Chinese patent medicine tablet for treating cardiovascular and cerebrovascular diseases, the main components and auxiliary materials are:

[0034] 30g Ginkgo biloba extract, 10g Polygonum multiflorum extract, 10g Uncaria extract, 50g carrier PVP-K30, 50g soluble starch, 30g magnesium stearate.

[0035] The preparation method of the present invention comprises: pulverizing the extract of ginkgo biloba, the extract of Polygonum multiflorum, and the extract of Uncaria uncaria into powder, passing through a 100-mesh sieve, and passing the remaining substances through a 100-mesh sieve respectively. Mix the three kinds of medicines, carrier and soluble starch evenly in proportion, add appropriate amount of water to make it sticky. Dry in an electric thermostat oven with a set temperature of 70°C. After the medicine is dry, crush it with a pulverizer and pass through a 100-mesh sieve. Set the tablet pressing pressure of the tablet press to 10KN, the filling depth to 12mm, ...

Embodiment 3

[0037] A Chinese patent medicine tablet for treating cardiovascular and cerebrovascular diseases, the main components and auxiliary materials are:

[0038] 40g Ginkgo biloba extract, 20g Polygonum multiflorum extract, 20g Uncaria extract, 100g carrier PVP-K30, 80g soluble starch, 40g magnesium stearate.

[0039] The preparation method of the present invention comprises: pulverizing the extract of ginkgo biloba, the extract of Polygonum multiflorum, and the extract of Uncaria uncaria into powder, passing through a 100-mesh sieve, and passing the remaining substances through a 100-mesh sieve respectively. Mix the three kinds of medicines, carrier and soluble starch evenly in proportion, add appropriate amount of water to make it sticky. Dry in an electric thermostat oven with a set temperature of 70°C. After the medicine is dry, crush it with a pulverizer and pass through a 100-mesh sieve. Set the tablet pressing pressure of the tablet press to 10KN, the filling depth to 12mm,...

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Abstract

The invention discloses Chinese patent medicine tablets for treating cardiovascular and cerebrovascular diseases. The Chinese patent medicine tablets comprise main drugs and auxiliary materials, wherein the main drugs consist of the following raw material medicines in parts by weight: 20-40 parts of ginkgo leaf extract, 10-20 parts of polygonum multiflorum extract and 10-20 parts of uncaria extract; and the auxiliary materials are prepared from the following substances in parts by weight: 40-80 parts of soluble starch and 20-40 parts of magnesium stearate. According to the formula disclosed by the invention, the advantages of the effects of the ginkgo leaf extract, the polygonum multiflorum extract and the uncaria extract in the aspect of treating the cardiovascular and cerebrovascular diseases to the human body are fully complemented, the limitation of single drug use effects is overcome, the effect of improving the cardiovascular and cerebrovascular diseases is achieved by using reasonable formula and amount, the drug effect is far superior to that of a single plant extract, and the formula is simple, does not have any toxic or side effect, can be used for a long time and is suitable for middle aged and elderly people and sub-health crowds.

Description

technical field [0001] The present invention relates to the preparation of medicinal dosage forms of plant extracts, in particular to a Chinese patent medicine tablet for treating cardiovascular and cerebrovascular diseases and its preparation method Background technique [0002] The main medicinal components of Ginkgo biloba extract are flavonoids and terpenoid lactones. Pharmacological tests have shown that ginkgo flavonoids can dilate coronary vessels and other blood vessels, total flavonoids of ginkgo can resist free radicals and inhibit lipid peroxidation, and ginkgolides can antagonize platelet activating factor (PAF). Ginkgo biloba series preparations are effective substances extracted from Ginkgo biloba leaves. The advent and successful clinical application of Ginkgo biloba preparations has become a milestone in the history of herbal medicine development. [0003] There are many studies on the preparation of various dosage forms of Chinese patent medicines with Gink...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K9/28A61P9/00
CPCA61K9/2866A61K36/16A61K36/704A61K36/74A61K2300/00
Inventor 杨荣华盛现波杨明晖张秀玲
Owner TAISHAN MEDICAL UNIV
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