A fingerprint detection method of anti-tumor traditional Chinese medicine composition

A fingerprint and detection method technology, which is applied in the field of fingerprint detection of traditional Chinese medicine compositions, can solve the problems of inability to comprehensively and objectively detect and evaluate the quality of Tianfoshen Oral Liquid

Active Publication Date: 2016-03-30
常熟雷允上制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, Acanthopanax ovalifolia, kiwi fruit root, and sea buckthorn fruit are extracted by water extraction process, and American ginseng, asparagus, and soil Fritillaria are extracted by alcohol extraction process. The polarity of the compounds contained in the total extract covers the range of strong polarity and medium polarity. The detection methods of the prior art cannot comprehensively and objectively detect and evaluate the quality of Tianfoshen Oral Liquid

Method used

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  • A fingerprint detection method of anti-tumor traditional Chinese medicine composition
  • A fingerprint detection method of anti-tumor traditional Chinese medicine composition
  • A fingerprint detection method of anti-tumor traditional Chinese medicine composition

Examples

Experimental program
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Effect test

Embodiment 1

[0111] 1. A fingerprint detection method of an anti-tumor Chinese medicine composition. In parts by weight, the Chinese medicine composition is composed of 50 parts of American ginseng, 0.25 part of toad venom, 167 parts of asparagus, 200 parts of S. 599 parts of Acanthopanax, 1000 parts of kiwi fruit root, 333 parts of seabuckthorn fruit, and 167 parts of bergamot are made into oral liquid preparations, and the fingerprint detection method comprises the following steps:

[0112] (1) Preparation of the test solution: get the Chinese medicine composition, and make the test solution after being processed by an appropriate method;

[0113] (2) The contrast fingerprint of this product is determined by high performance liquid chromatography: get more than 10 batches of traditional Chinese medicine composition test samples to inject samples under appropriate chromatographic conditions, record the fingerprints of each batch of test samples, and use these fingerprints Based on the spe...

Embodiment 2

[0124] A method for detecting fingerprints of an anti-tumor traditional Chinese medicine composition. In parts by weight, the traditional Chinese medicine composition is composed of 50 parts of American ginseng, 0.25 parts of toad venom, 167 parts of asparagus, 200 parts of S. 599 parts, 1000 parts of kiwi fruit root, 333 parts of seabuckthorn fruit, and 167 parts of bergamot are made into oral liquid preparations, and the fingerprint detection method comprises the following steps:

[0125] (1) Preparation of the test solution: get the Chinese medicine composition, and make the test solution after being processed by an appropriate method;

[0126] (2) The contrast fingerprint of this product is determined by high performance liquid chromatography: get more than 10 batches of traditional Chinese medicine composition test samples to inject samples under appropriate chromatographic conditions, record the fingerprints of each batch of test samples, and use these fingerprints Based...

Embodiment 3

[0137] A method for detecting fingerprints of an anti-tumor traditional Chinese medicine composition. In parts by weight, the traditional Chinese medicine composition is composed of 60 parts of American ginseng, 0.30 parts of toad venom, 180 parts of asparagus, 210 parts of S. 620 parts, 1100 parts of kiwifruit roots, 340 parts of sea buckthorn fruit, and 210 parts of bergamot are made into oral liquid preparations, and the fingerprint detection method comprises the following steps:

[0138] (1) Preparation of the test solution: get the Chinese medicine composition, and make the test solution after being processed by an appropriate method;

[0139] (2) The contrast fingerprint of this product is determined by high performance liquid chromatography: get more than 10 batches of traditional Chinese medicine composition test samples to inject samples under appropriate chromatographic conditions, record the fingerprints of each batch of test samples, and use these fingerprints Base...

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PUM

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Abstract

The invention discloses a fingerprint detection method for an antitumor traditional Chinese medicine composition. The composition is prepared from American ginseng, venenum bufonis, asparagus cochinchinensis, rhizoma bolbostemmae, acanthopanax obovatus hoo, Chinese actinidia root, fructus hippophae and fingered citron as crude drugs. Multiple experiments prove that the quality of the composition can be comprehensively, objectively and accurately detected and evaluated by the fingerprint detection method disclosed by the invention; and the clinical curative effect is ensured.

Description

technical field [0001] The invention relates to a fingerprint detection method of a traditional Chinese medicine composition, in particular to a fingerprint detection method of a traditional Chinese medicine composition with anti-tumor effect. Background technique [0002] Tianfoshen oral liquid is a pure natural traditional Chinese medicine preparation refined and refined by modern advanced technology. It is produced by Changshu Leiyunshang Pharmaceutical Co., Ltd. It has the effects of nourishing yin and replenishing qi, detoxifying and dispelling stagnation, and it is used in combination with anti-tumor chemicals It is used for non-small cell lung cancer with deficiency of both qi and yin, and can relieve nausea, vomiting, constipation, hair loss and other phenomena caused by chemotherapy. It has been widely used in clinical practice, and its curative effect is accurate and reliable. Among them, Tianfoshen Oral Liquid is composed of 8 medicinal materials: American ginseng...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/02
Inventor 顾治平阙瑞艳王恒斌陈力建张礼学
Owner 常熟雷允上制药有限公司
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