High-efficiency high-yield preparation method of panax notoginseng extract

Abstract

The invention discloses a high-efficiency high-yield preparation method of a panax notoginseng extract. The high-efficiency high-yield preparation method of the panax notoginseng extract comprises the steps of taking fresh panax notoginseng as a raw material, homogenizing, performing freeze drying and extracting. The method specifically comprises the following steps: taking the fresh panax notoginseng as the raw material, adding water according to the weight ratio of 0.05-0.50 time, homogenizing to obtain a panax notoginseng slurry, and performing freeze drying, thereby obtaining panax notoginseng powder; adding an ethanol solution in a weight amount of 3-8 times into the panax notoginseng slurry, leaching at the temperature of 20-35 DEG C for 0.5-3.0 hours, filtering, and concentrating, thereby obtaining a target panax notoginseng extract; and adding an ethanol solution in a weight amount of 5-15 times into the panax notoginseng slurry, leaching at the temperature of 20-35 DEG C for 1-4 hours, filtering, and concentrating, thereby obtaining the target panax notoginseng extract. By utilizing the characteristics that fresh panax notoginseng cells are full, the cell structure is easy to damage and the active ingredients can be efficiently dissolved, the panax notoginseng powder is prepared by combining a low-temperature freeze drying method by adopting a homogenizing technology; and moreover, the characteristic that the active ingredients are free in the panax notoginseng powder and are easy to dissolve is utilized, the active ingredients can be directly extracted and enriched, the panax notoginseng extract is prepared, and the defects of the traditional method for preparing the panax notoginseng powder by disintegrating the panax notoginseng medicinal materials and performing reflux extraction to produce the panax notoginseng extract are overcome.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a high-efficiency and high-yield preparation method of a Panax notoginseng extract. Background technique [0002] Panax notoginseng is the dry root of Panax notoginseng (Burk) F. H. Chen. Panax notoginseng was first recorded in "Compendium of Materia Medica", and modern "Chinese Materia Medica" listed it as a blood-invigorating medicine. Traditional Chinese medicine is used as a medicine for removing blood stasis and stopping bleeding, reducing swelling and analgesia. It has the characteristics of "stopping bleeding without leaving stasis". Panax notoginseng contains saponins, notoginseng, flavonoids, volatile oils, amino acids, sugars and other active ingredients. Its total saponin content is about 12%, which is the main active ingredient of panax notoginseng. Modern pharmacological research has found that the pharmacological activity of the total saponins of Pana...

AI Technical Summary

Problems solved by technology

Since the plant cells have been dehydrated, the active ingredients must be dissolved from the dry and solidified cells. Despite the adoption of various modern methods and technologies, there are still constraints between cost and yield.

[0004] Panax notoginseng is known for its hard texture and is described as a "copper-skinned iron bone lion's head". It is more time-consuming and labor-intensive to crush it, and the continuous high temperature during the drying and crushing process causes a greater loss of active ingredients in Panax notoginseng

These methods are all: the percolation method takes a long time, the amount of solvent is large, and the solvent recovery rate is low; the active ingredient of the reflux method is partially degraded due to heating for a long time, so that the yield of the active ingredient is reduced; although ultrasonic or microwave-assisted methods can accelerate the extraction speed, Improve the yield, but at present, industrial equipment consumes a lot of energy and is noisy, making it difficult for industrial applications

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