Composite bactericide of nano-silver and polyhexamethylene guanidine and processing technology of composite bactericide

A technology of polyhexamethylene guanidine and compound fungicides, which is applied in the direction of fungicides, biocides, antifungal agents, etc., can solve the problems of low sterilization efficiency, harm to human body, and short drug effect period, so as to improve the sterilization efficiency , Ease of popularization and cost reduction

Inactive Publication Date: 2015-04-22
ANHUI HANCHI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Fungicides include organic fungicides and inorganic fungicides. The dosage of organic fungicides is small and the sterilization efficiency is high. However, long-term use makes fungi prone to drug resistance. The use of fungicides needs to continue to increase, and the final effect is getting smaller and smaller.
Another weakness is that organic fungicides are prone to failure and have a short efficacy period
The dosage of inorganic fungicides is large, the sterilization efficiency is low, and the toxicity is high
However, inorganic fungicides often have a long duration of efficacy and do not produce drug resistance. Now polyhexamethyleneguanidine is a very effective environmental-friendly organic fungicide. It has very low toxicity and does not cause harm to the human body, but it also has the potential to produce resistance. The problem of short duration of drug and drug effect
Silver is a metal that is friendly to the human body. Silver salt fungicides are popular because of their high sterilization rate and long-lasting efficacy. However, silver salts are oxidative fungicides, and improper use can easily cause harm to the human body.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 0.5 grams of nano silver, 10 grams of polyhexamethylene guanidine, 1 gram of dodecyltrimethylammonium bromide, 5 grams of acetamide, 10 grams of glycine, and the rest are pharmaceutical grade purified water. Dissolve polyhexamethyleneguanidine in water at room temperature, then add dodecyltrimethylammonium bromide, glycine and acetamide, stir well, and finally add nano-silver, stir well, and filter.

Embodiment 2

[0025] 0.01 grams of nano silver, 20 grams of polyhexamethylene guanidine, 2 grams of cetyltrimethylammonium bromide, 2 grams of sodium polyacrylate, 15 grams of glutamic acid, and the rest are pharmaceutical grade purified water. Dissolve polyhexamethylene guanidine in water at room temperature, then add hexadecyltrimethylammonium bromide, glutamic acid and sodium polyacrylate, stir well, and finally add nano-silver, stir well, and filter. .

Embodiment 3

[0027] 0.15 grams of nano silver, 18 grams of polyhexamethylene guanidine, 3 grams of Tween 80, 1 gram of caprolactam, 20 grams of alanine, and the rest is pharmaceutical grade purified water. Dissolve polyhexamethyleneguanidine in water at room temperature, then add Tween 80, alanine and caprolactam, stir well, finally add nano-silver, stir well, and filter.

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Abstract

The invention relates to a composite bactericide of nano-silver and polyhexamethylene guanidine and a processing technology of the composite bactericide. The composite bactericide comprises the nano-silver, the polyhexamethylene guanidine, dispersing agents, stabilizers, complexing agents and water. The composite bactericide is a water solution, the mass ratio of the nano-silver to the polyhexamethylene guanidine is (1:100)-(1:10000), the total mass of the nano-silver and the polyhexamethylene guanidine accounts for 1%-50% of the total solution mass, the mass of the dispersing agents accounts for 0.1%-10% of the total solution mass, the mass of the stabilizers accounts for 0.1%-10% of the total solution mass, the mass of the complexing agents accounts for 1%-30% of the total solution mass, and the balance is the water. The composite bactericide is high in sterilization efficiency and low in cost.

Description

technical field [0001] The invention relates to the technical field of material chemistry, in particular to a composite bactericide of nano silver and polyhexamethylene guanidine. Background technique [0002] Fungicides include organic fungicides and inorganic fungicides. Organic fungicides are used in a small amount and have high sterilization efficiency. However, long-term use makes fungi prone to drug resistance. The use of fungicides needs to continue to increase, and the final effect is getting smaller and smaller. Another weakness is that organic fungicides are prone to failure and have a short efficacy period. Inorganic fungicides have large dosage, low sterilization efficiency and high toxicity. However, inorganic fungicides often have a long duration of efficacy and do not produce drug resistance. Now polyhexamethyleneguanidine is a very effective environmental-friendly organic fungicide. It has very low toxicity and does not cause harm to the human body, but it a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/16A01P1/00A01P3/00A61K33/38A61P31/02A61P31/10A61P27/02A61P17/00A61P15/02A01N47/44A61K31/785
Inventor 张星辰张建江张磊
Owner ANHUI HANCHI BIOTECH
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