85results about How to "Less prone to drug resistance" patented technology

The invention relates to the application of gallnut extract as the antiseptic and antiseptic containing the gallnut extract. The gallnut extract mainly comprises at least one of the following extracted compounds: Chinese tannin, five gallanilide glucose (1, 2, 3, 4 and 6-Five-O- gallanilide-Beta-D-glucose) and multiply gallanilide glucose (Six or Seven to twevel gallanilide glucose). The invention has good effects for preventing and curing a plurality of crop diseases and is good for environment, which is characterized by low residue, high prevention effect, a plurality of action points and difficulty of generating drug resistance for germina.

The invention relates to the technical field of red fire ant drugs, in particular to a bait type red fire ant drug. Effective ingredients of the bait by weight percentage are 0.01 percent-5 percent of insecticidal active ingredient extracted from insecticidal plants, and teh active ingredient can be one or more of rotenone, matrine, strophanthus divaricatus glycoside, coniine, celangulin and veratrine, 4 percent-40 percent of edible micro-capsule embedding medium, 54.7 percent to 95.89 percent of eating action tempting material that is one or the mixture of animal protein, vegetable protein, glucide, grease and spice and 0.1 percent -0.3 percent of potassium sorbate or sodium sorbate as preservative. The effective ingredients of the bait are extracted from natural plants, thus being degraded in environment timely, and the oxygenolysis speed of the bait can be controlled by introducing controlled release technology. The bait can kill all red fire ants in a nest by alluring ergates of red fire ants to carry the bait to the nest, taking advantage of the habit of cross feeding one to another and passing toxicity to queen ant and other individuals.

The invention relates to an antibacterial functionalized artificial joint with a silver-loaded nanotube array surface. The surface of a metal substrate of the artificial joint is provided with a silver-doped sodium titanate nanotube array layer with a tubular structure. The inside of the silver-doped sodium titanate nanotube array layer is further loaded with bone morphogenetic protein (BMP). A preparation method of the antibacterial functionalized artificial joint with the silver-loaded nanotube array surface comprises the following steps: firstly selecting pure titanium or titanium alloy to process the artificial joint; then adopting the two-step anodizing technology to obtain a titanium dioxide nanotube array layer with a tubular structure on the surface of the pure titanium or titanium alloy artificial joint; adopting the alkaline hydrothermal synthesis technology to convert the titanium dioxide nanotube array layer into the sodium titanate nanotube array layer; doping trace silver in the sodium titanate nanotube array layer by solution impregnation iron exchange; and finally adopting the centrifugal load technology to load the bone morphogenetic protein in the silver-doped sodium titanate nanotube array layer.

The invention provides a sterilization mixed preparation which has environment compatibility and is prepared from a plant source active substance mustard essential oil and allicin in the weight ratio of (1:10)-(10:1). The mixed preparation has a remarkable synergistic interaction function, can be prepared into preparations such as emulsion in water, suspension, water dispersible granules and the like, and can be used for preventing and controlling diseases such as plant powdery mildew, gray mold, phytophthora, anthracnose, wilt, downy mildew and the like, so that the prevention and control effect is improved, the dosage is reduced, the pesticide delivery time is reduced, the prevention and control range is enlarged, the requirements of the technique that the amount of pesticide is reduced are met, and moreover the preparation provided by the invention is an environment-friendly preparation, has the potential to be further developed into safe, efficient, low-toxicity and excellent sterilization agent, and is good in popularization and application prospect.

The invention provides a pregnant sow traditional Chinese medicine health feed and a preparation method thereof, and belongs to the technical field of feeds. The pregnant sow traditional Chinese medicine health feed is suitable for Xiangxi black pigs. The pregnant sow traditional Chinese medicine health feed includes, by weight: corn, soybean meal, wheat bran, folium eucommiae, a pregnant sow compound premix, compound probiotics, yeast cell walls and compound traditional Chinese medicine additives. The compound Chinese medicine additives include radix astragali, radix codonopsis, radix angelicae sinensis, radix achyranthis bidentatae, rhizoma atractylodis macrocephalae, liquorice root, poria cocos and fructus amomi. The preparation method is as below: smashing the corn, the soybean meal, the folium eucommiae, the wheat bran, and the compound traditional Chinese medicine additives to obtain mixed powder, mixing the mixed powder with the pregnant sow compound premix, the compound probiotics and the yeast cell walls, and conducting granulating. The pregnant sow traditional Chinese medicine health feed prepared through the preparation method has the effects of tranquilizing mind, preventing miscarriage, regulating spleen and stomach functions, activating intestinal flora, and reducing constipation. The pregnant sow traditional Chinese medicine health feed tends not to exhibit residuals, or cause drug resistance and toxic side effects, and is safe and reliable.

The invention discloses a method for preparing a chelerythrine medicament and application thereof in prevention and treatment of bacterial diseases of aquatic animals. The medicament consists of chelerythrine and starch serving as an auxiliary material. The method for preparing the prevention and treatment agent comprises the following steps of: weighing chelerythrine extract (the purity is 80 percent) and starch serving as the auxiliary material, adding the chelerythrine extract and the starch into a mixer, and mixing the chelerythrine extract and the starch uniformly to obtain a preparation containing 5 to 20 percent chelerythrine. When the bacterial disease prevention and treatment agent is added into feed for feeding, the dosage is 200 to 250 mg/kg (according to the quantity of the chelerythrine for each kilogram of weight); the prevention and treatment agent added in the feed has low toxicity, does not affect the quality of aquatic products, has no residue or pollution, is not easy to generate medicament resistance, does not affect the feed and growth of the aquatic animals, has low dosage, and is widely applied in prevention and treatment of bacterial hemorrhage diseases of mandarin fish, weever, carp, grass carp, eel, porgy, flounder and the like.

The invention provides milking sow traditional Chinese medicine healthcare feed and a preparation method thereof, and belongs to the technical field of feed. The milking sow traditional Chinese medicine healthcare feed is suitable for black pigs in western Hunan; the milking sow traditional Chinese medicine healthcare feed is prepared from the following raw materials in parts by weight: corns, soybean meal, folium eucommiae, milking sow compound premix, compound probiotics, oil meal and a composite traditional Chinese medicine additive, wherein the composite traditional Chinese medicine additive is prepared from herba taraxaci, semen vaccariae, rhizoma chuanxiong, bighead atractylodes rhizome, rhizoma dioscoreae and cortex magnoliae officinalis. The preparation method of the milking sow traditional Chinese medicine healthcare feed comprises the following steps: smashing the corns, the soybean meal, the folium eucommiae and the composite traditional Chinese medicine additive, thus obtaining mixed powder; mixing the mixed powder with the milking sow compound premix, the compound probiotics and the oil meal, and pelletizing. The milking sow traditional Chinese medicine healthcare feed prepared through the preparation method has the functions of increasing the feed intake and the lactation yield of a milking sow, reducing the occurrence of postnatal diseases of the milking sow and increasing the survival rate of piglets, residue, drug resistance and toxicity and side effects are not easy to generate, and safety and reliability are achieved.

The invention provides a Bacillus mojavensis QLY002 strain. The Bacillus mojavensis QLY002 strain has a preservation number of CGMCC No. 8905. The invention also provides a microbial inoculum of the Bacillus mojavensis QLY002 strain and its preparation method and use in potato pathogen inhibition and potato growth promotion. The Bacillus mojavensis QLY002 strain and the microbial inoculum can be used as microbe pesticides and fertilizer, can inhibit Phoma foveata, Alternaria solani, Fusarium oxysporum and Colletotrichum coccodes, have an antibacterial rate more than 61%, have potato growth promotion effects, can be used as potato special-purpose microbial pesticide and microbial fertilizer, solve the problem that the existing chemical pesticide has poor environmental friendliness, easily causes pesticide resistance and has poor safety, and have the advantages of good environmental friendliness, no pesticide resistance and good safety.

The invention discloses a preparation method and application of quaternary ammonium salt-N-halamine nano antibacterial fibers. The preparation method includes: performing activation preprocessing on natural fibers, allowing the activated natural fibers to have grafting reaction with a multi-amino polymer compound or a multi-amino multi-sulfydryl polymer compound, then grafting with quaternary ammonium salt, using a crosslinking agent to perform crosslinking, and bleaching to obtain the quaternary ammonium salt-N-halamine nano antibacterial fibers. The prepared quaternary ammonium salt-N-halamine nano antibacterial fibers have contact type and release type bifunctional antibacterial functions and are capable of increasing sterilizing speed, capable of achieving sterilizing under normal temperature, high in sterilizing performance, lasting in effect, less prone to tolerance generation, widely applicable to many fields such food packages, food fresh-keeping, medical equipment, public sanitation and water purification systems and promising in application prospect.

The invention discloses bacillus velezensis HY19 and application thereof. The strain Bacillus velezensis HY19 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation date is January 4, 2021, and the preservation number is CGMCC No.21590. The strain can generate various water-soluble and volatile antibacterial substances, can effectively antagonize various plant pathogenic fungi, is wide in antibacterial spectrum and strong in antibacterial effect, has a relatively good biological prevention and treatment effect on flue-cured tobacco brown spot, is harmless to the ecological environment, and is not easy to cause drug resistance of pathogens. The strain has the characteristics of high breeding speed, high environmental adaptability, simple nutritional requirements, wide disease-resistant spectrum and the like, and is a novel biocontrol microorganism which is safe, efficient and capable of preventing and treating fungal diseases of plants in a broad-spectrum manner. The biocontrol microbial agent of the invention is simple in preparation method, easy for industrial production, and has good development and application prospects.

The invention discloses a new prevention method of citrus yellowshoot. The method covers an insect-proof screen and a farm film to perform physical shield, and applies nutrient to supplement nutritionto plants, thus the plant immunity is improved, and orange tree can be prevented by adjusting PH value of soil. A sick tree is treated by chemical drug firstly while the root part is treated; the sick tree is performed with biological drug treatment by mixing concentrated solution prepared from azedarach, ailanthus, lettuce, cordate houttuynia, rheum officinale, mangnolia officinalis, folium artemisiae argyi and other Chinese herbal medicines and adding with plant growth hormone and inorganic salt synthesis agent. Through implementing the work, the sick tree of the orange tree is recovered, thus the citrus yellowshoot can be prevented, controlled, and treated; the method takes prevention mainly and treatment secondly, and combines prevention and treatment; the method is simple in operation, scientific and high-efficient in use, low in running cost, complete in prevention, good in treatment effect, and not easy to appear dust resistance and others.

The invention provides a traditional Chinese medicine health-care feed for middle and big pigs and a preparation method of the traditional Chinese medicine health-care feed, and belongs to the technical field of feed. The traditional Chinese medicine health-care feed for middle and big pigs comprises the following raw materials in parts by weight: corn, bean pulp, folium cortex eucommiae, compound premix for middle and big pigs, compound probiotic, coated allicin and a compound traditional Chinese medicine additive. The composite traditional Chinese medicine additive comprises dandelion, radix achyranthis bidentatae, bighead atractylodes rhizome, uncaria rhynchophylla, rhizoma zingiberis and hawthorn. The preparation method comprises the following steps: pulverizing the corn, the bean pulp, the folium cortex eucommiae and the compound traditional Chinese medicine additive to obtain mixed powder; and mixing the mixed powder with the compound premix for middle and big pigs, the compound probiotic and the coated allicin and granulating. The traditional Chinese medicine health-care feed for middle and big pigs, which is prepared by the preparation method, can improve the immunity of the middle and big pigs, the morbidity is reduced, the functions of the spleen and stomach are regulated, the feed intake is increased, digestive absorption abilities are improved, growth is promoted, flavor of pork is improved, residues, resistance to drugs and toxic and side effects cannot be caused easily, and the traditional Chinese medicine health-care feed for middle and big pigs has safety and reliability.

The invention relates to the technical field of antibacterial mildew inhibitors, and provides a long-acting antibacterial mildew inhibitor, a preparation method thereof, and an application of the long-acting antibacterial mildew inhibitor in a space station environment. The long-acting antibacterial mildew inhibitor takes an organosilicon quaternary ammonium salt as a main sterilization component,can inhibit bacteria, saccharomycetes and fungi for a long time, is high in safety, and has no acute toxicity or accumulated toxicity hidden danger; the antibacterial mildew inhibitor has long-actingantibacterial and mildew-proof performance, and bacteria and mildew do not easily generate drug resistance; no color change hidden danger or toxic component exists, and long-term storage can be achieved; and furthermore, propylene glycol and the like are used as stabilizers, so the VOC release amount can be reduced, and the situation that toxic gas such as methyl alcohol volatilizes in the special environment of the space station and affects the health of astronauts is avoided. The long-acting antibacterial mildew inhibitor can meet the long-acting antibacterial and mildew-proof requirementsof aluminum alloy and textiles in a space station cabin, the VOC release amount of the product is low, and the air quality requirement of the space station is met.

The invention discloses a synergistic insecticide of plant source and a preparation method thereof. The insecticide uses nicotine in tobacco stem extracts, sanguinarine and chelerythrine in cordata cordata extracts, and rhodojaponin in Rhododendron molle extracts as the active substances of the insecticide, uses ramie oil, ortho-hydroxybenzoic acid and turpentine as synergistic agents, by adding an appropriate amount of environment-friendly solvent, biologically degradable emulsifiers, anti-freezing agent, thickener and defoaming agent, and using low energy emulsification method to prepare a stable nano water emulsion. The synergistic insecticide of plant source is a pure plant source insecticide, has no chemical pesticide contents, has good preventive effect to aphids and rice planthopper in crops, is safe to human and livestock, causes no pollution to environment, is not prone to trigger resistance to the insecticide, is prone to degrade in natural environment, and the like. The synergistic insecticide of plant source has huge application and promotion value in organic agricultural productscultivation, and is an ideal novel green insecticide.

The invention provides a formulation and a preparation method of a Chinese herbal feed additive for livestock and poultry. The additive comprises the following components by weight: 25-40 parts of Phyllanthus urinaria, 15-25 parts of Gelsemium elegans Benth, 25-35 parts of Artemisia annua, 5-15 parts of Flos Daturae, and 5-15 parts of ambrette seeds. The raw materials adopted by the additive are all produced by manual labor according to GAP standards, so that the additive has multifunctionality, naturalness, low t toxic and side effect and other advantages, does not contain antibiotics and heavy metals, and is difficult to generate drug resistance. The feces from animal products are directly applied to various crops, thus having little pollution to the environment. Meanwhile, the mountain waste and desolate lands in rural areas are utilized to plant the raw materials, so that the land is sufficiently utilized, and the income of farmers is increased.

The invention provides traditional Chinese medicine health fodder for piglets and a preparation method of the fodder and belongs to the technical field of fodder. The traditional Chinese medicine health fodder for the piglets is applicable to black pigs in western Hunan and is prepared from corn, soybean meal, eucommia ulmoides leaves, compound premix for piglets, compound probiotics, montmorillonite and a compound traditional Chinese medicine additive, wherein the compound traditional Chinese medicine additive is prepared from Chinese yams, radix achyranthis bidentatae, rhizoma atractylodis macrocephalae, cinnamon, poria cocos and hawthorn fruits. According to the preparation method of the traditional Chinese medicine health fodder, the corn, the soybean meal, the eucommia ulmoides leaves and the compound traditional Chinese medicine additive are crushed, mixed powder is obtained and mixed with the compound premix for the piglets, the compound probiotics and montmorillonite, and the mixture is granulated. The traditional Chinese medicine health fodder prepared with the preparation method can promote development of immune organs of the piglets, improve the functions of the liver and the kidney, regulate the functions of the spleen and the stomach, promote establishment of intestinal flora, improve the immunity of the piglets and reduce the morbidity and the death rate of the piglets, has low probability of residues, drug resistance and toxic and side effects and is safe and reliable.

The invention relates to a vegetable insecticide. The vegetable insecticide comprises following components in parts by weight: 10-15 parts of potassium sulfate, 10-15 parts of sophocarpidine, 1-5 parts of tetramethrin, 0.1-0.5 part of citric acid, 15-25 parts of ammonium phosphate, 2-6 parts of sodium borate and 4-10 parts of citric dibutyl calcium naphthalenesulfonate. The vegetable insecticide provided by the invention has the advantages of reasonable formula, low cost, obvious insect killing effect and no damage on plants.

The invention discloses a nano composite material based on enzyme degradation enhanced photo-thermal removal of bacterial biofilms, and a preparation method and application of the nano composite material. The nano composite material is a MnO2 nano sheet (namely MnO2-amylase-PEG-ICG NSs, MAPI for short) modified by amylase, polyethylene glycol (PEG) and indocyanine green (ICG). The material can degrade extracellular polymers (EPS) of a biofilm through the amylases, damage the structure of the biofilm, and further enhance the photo-thermal sterilization effect of the ICG. The MAPI provided by the invention has the advantages of good stability, excellent bacteria killing effect in a biofilm and small cytotoxicity, and can meet basic conditions of biological medicine application.

The invention discloses urban and rural garbage fermentation liquid and a preparation method thereof. The urban and rural garbage fermentation liquid is prepared from the following raw materials in part by weight: 1 to 5 parts of EM liquid, 1 to 15 parts of raising agent and 1 to 10 parts of leavening agent. The urban and rural garbage fermentation liquid is prepared by the following steps of: adding the EM liquid, the raising agent and the leavening agent in the weight ratio to stir uniformly; and adjusting the pH value to be 4.6 to 4.8 by using caustic soda to obtain the product, wherein a preparation method of the EM liquid comprises the following steps of: preparing 50 milliliters of mixed solution of thermophilic sporotrichum, phanerochaete chrysosporium, lactobacillus bulgaricus and saccharomycetes in a ratio of 1:1:1:1; mixing the 50 milliliters of mixed solution, 20 to 40 grams of brown granulated sugar, 100 milliliters of rice vinegar and 100 milliliters of 30-degree to 50-degree spirit uniformly; and cultivating the mixture at the temperature of between 28 and 32 DEG C for 5 to 7 days to obtain 250 milliliters of EM liquid. By the urban and rural garbage fermentation liquid and the preparation method thereof, the urban and rural garbage can be converted into organic fertilizer which can prevent and control germs, can increase yield, can improve quality, and does not have toxicity, pollution and residuals.

The invention relates to a pesticide composition and applications thereof in preventing and controlling saffron crocus corm rot. Active ingredients of the pesticide composition are basic chrome sulphate, mancozeb and fludioxonil, wherein the mass ratio of basic chrome sulphate, mancozeb and fludioxonil is (50-72):(27.5-82.5):(0.6-6.3). The invention also provides the applications of the pesticide composition in preventing and controlling saffron crocus corm rot. Control efficiency of the pesticide composition on saffron crocus corm rot is excellent, and the control efficiency is increased significantly compared with that of utilization of only one ingredient selected from basic chrome sulphate, mancozeb or fludioxonil.

The invention provides a biological rodenticide with multiple deratization effects, which comprises the following raw materials in parts by weight: 40-60 parts of blue-green algea mud and 15-25 partsof tripterygium wilfordii micro powder. The toxic component blue-green algea toxin contained in the blue-green algea mud is combined with the tripterygium wilfordii micro powder, so that a remarkablesynergistic effect is achieved; the prepared rodenticide has an antifertility effect on male rats, also has a remarkable antifertility effect on female rats, and has a poisoning effect and an anticoagulation effect on various harmful rats; and the rodenticide disclosed by the invention is prepared from pure natural raw materials, does not pollute the environment, does not easily cause drug resistance, does not generate a secondary poisoning phenomenon, is easy to naturally degrade, and belongs to a green and safe biological rodenticide.

The invention discloses a pharmaceutical composition for killing diamondback moth, including alum extract, dry lacquer charcoal extract, torreya extract, polygala extract, jackfruit extract, caperia japonica extract, and inula inula extract , Scrophulariaceae extract, Qingpi extract and toosendanin. The pharmaceutical composition described in the present invention can kill Plutella xylostella in a targeted manner without any toxic and side effects on natural enemies of Plutella xylostella, has good safety, good biodegradation, no pollution and irritating odor, and no environmental toxicity. There is no residue in the animal body, does not destroy the ecological balance, and has little impact on the crop growth environment; it has good permeability and moisture, interferes with the nervous system of the insect body, inhibits the synthesis and development of insect eggs, and is not easy to develop drug resistance; quick-acting Well, it is suitable for widespread application in pest control.

The invention discloses a plant-derived antioxidant for treating psoriasis and a preparation method thereof. The pure plant natural antioxidant preparation product comprises polygonum cuspidatum, senecio scandens, usnea, cactus, marigold and other plants. The preparation method comprises the following steps of: adding water which is 10-30 times the weight of the raw materials into the plant raw materials, performing water extraction at a certain temperature for 1-3 hours, extracting for 2-3 times, and merging the extracting solutions, thereby obtaining water extracts of the raw materials; and respectively preparing solutions with crude drug concentration of 1g/L by utilizing the water extracts of the pure plant raw materials, and mixing according to an accurate ratio, thereby forming the pure plant natural antioxidant preparation product which is high in damaged skin repairing capacity, fast in itching relieving and free of toxic or side effect. The antioxidant is non-irritating, free of toxic or side effect, free of residue, stable, safe and high-efficiency.