Traditional Chinese medicine granules and preparation method and use thereof

A technology of traditional Chinese medicine granules and traditional Chinese medicine, which is applied in the direction of medical formulas, drug combinations, and medical preparations containing active ingredients, etc. It can solve problems such as difficult product quality control, low production automation level, and inconvenience in taking, and achieve easier product quality control. The effect of improving the level of production automation

Inactive Publication Date: 2015-04-22
BEIJING HANDIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the Pharmacopoeia, the preparation process of Guizhi Fuling pills is as follows: pulverize into fine powder, sieve, mix, and add honey to make it. This traditional raw powder dosage form has a low level of production automation, large dosage, and inconvenient administration. , and product quality is not easy to control

Method used

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  • Traditional Chinese medicine granules and preparation method and use thereof
  • Traditional Chinese medicine granules and preparation method and use thereof
  • Traditional Chinese medicine granules and preparation method and use thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1 A kind of Chinese medicine granule and preparation method thereof

[0043] The prescription of traditional Chinese medicine granules includes: traditional Chinese medicine extracts and excipients prepared from raw materials.

[0044] The Chinese medicine extract is prepared from the following raw materials:

[0045] Guizhi 600g, Poria cocos 600g, Moutan bark 600g, red peony root 600g, peach kernel 600g

[0046] Excipients: Dextrin 560g

[0047] Chinese medicine granules are prepared by the following method:

[0048] (1) Prepare various medicinal materials according to the above prescription;

[0049] (2) Get cassia twig, peony cortex and add 8 times the water of medical material weight, steam distillation extracts volatile oil for 8 hours, and the aqueous solution after distillation is collected in another device, and medicine dregs is for subsequent use; Add appropriate amount of dehydrated ethanol to dissolve volatile oil, take by weighing β-cyclodext...

Embodiment 2

[0053] Embodiment 2 A kind of Chinese medicine granule and preparation method thereof

[0054] The prescription of traditional Chinese medicine granules includes: traditional Chinese medicine extracts and excipients prepared from raw materials.

[0055] The Chinese medicine extract is prepared from the following raw materials:

[0056] Guizhi 600g, Poria cocos 600g, Moutan bark 600g, red peony root 600g, peach kernel 600g

[0057] Accessories: dextrin 760g

[0058] Chinese medicine granules are prepared by the following method:

[0059] (1) Prepare various medicinal materials according to the prescription;

[0060] (2) Get cassia twig, tree peony bark and add 10 times the water of medical material weight, extract volatile oil by steam distillation for 10 hours, the aqueous solution after distillation is collected in another device, and medicinal residue is for subsequent use; Add appropriate amount of absolute ethanol to dissolve volatile oil, and take by weighing β-cyclod...

Embodiment 3

[0064] Embodiment 3 A kind of traditional Chinese medicine granule and preparation method thereof

[0065] The prescription of traditional Chinese medicine granules includes: traditional Chinese medicine extracts and excipients prepared from raw materials.

[0066] The Chinese medicine extract is prepared from the following raw materials:

[0067] Guizhi 600g, Poria cocos 600g, Moutan bark 600g, red peony root 600g, peach kernel 600g

[0068] Accessories: dextrin 240g

[0069] Chinese medicine granules are prepared by the following method:

[0070] (1) Prepare various medicinal materials according to the prescription;

[0071] (2) Get cassia twig, peony bark and add 6 times the water of medical material weight, extract volatile oil by steam distillation for 6 hours, the aqueous solution after distillation is collected in another device, and medicinal residue is standby; Add appropriate amount of absolute ethanol to dissolve volatile oil, and weigh Add β-cyclodextrin with 1...

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Abstract

The invention provides traditional Chinese medicine granules and a preparation method and use thereof. The traditional Chinese medicine granules are prepared from the following medicinal raw materials equal in weight: cassia twigs, poria cocos, moutan barks, red peony roots and peach kernels as well as a proper amount of auxiliary materials. The preparation method comprises the following steps: extracting volatile oil from cassia twigs and poria cocos; clathrating the volatile oil by beta-cyclodextrin; extracting residues with other medicinal raw materials by an ethanol solution with volume concentration of 70-90%; collecting and concentrating to obtain an alcohol extract; extracting the residues by water; collecting and concentrating; adding the alcohol extract; uniformly mixing; adding the proper amount of auxiliary materials and a volatile oil clathrate compound; granulating; and sub-packaging. The preparation method provided by the invention remarkably improves the pharmacodynamic action of cassia twigs and poria cocos, and the effect of the prepared traditional Chinese medicine granules in treating gynecological diseases, particularly gynecological chronic pelvic inflammatory disease, is remarkably improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a cinnamon twig and poria granule, a preparation method and application thereof. Background technique [0002] Guizhi Fuling Pills, the prescription comes from the "Chinese Pharmacopoeia" (Part 1, page 984). It is composed of 5 Chinese herbal medicines including Guizhi, Poria, Moutan Cortex, Radix Paeoniae Rubra, and Peach Kernel. It has the effects of promoting blood circulation, removing stasis, and eliminating symptoms. . The known main medicinal ingredients of Guizhi Fuling pills include cinnamaldehyde, paeonol, etc. Among them, the volatile oil contained in cinnamon sticks is relatively high, and the main component is cinnamaldehyde. Pharmacological research experiments have confirmed that cinnamaldehyde can dilate blood vessels and regulate blood circulation. , antibacterial, analgesic and other effects; Cortex Moutan and Radix Paeoniae Rubra both co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K36/736A61P15/00
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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