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Traditional Chinese medicinal composition for treating mastitis and breast distending pain, and preparation method and use thereof

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as poor patient compliance and affecting curative effect

Active Publication Date: 2015-05-06
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Poor patient compliance, thus affecting efficacy

Method used

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  • Traditional Chinese medicinal composition for treating mastitis and breast distending pain, and preparation method and use thereof
  • Traditional Chinese medicinal composition for treating mastitis and breast distending pain, and preparation method and use thereof
  • Traditional Chinese medicinal composition for treating mastitis and breast distending pain, and preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 A kind of Chinese medicine composition tablet

[0022] Raw material composition: (unit: Kg)

[0023] Dandelion 40, Gualou skin 40; Tu Fritillaria 25, Yuanhu 10.

[0024] Prepared by:

[0025] (1) Add water to decoct the raw material three times, add 11 times the amount of water for the first time, decoct for 3 hours; add 7 times the amount of water for the second time, decoct for 1 hour; add 7 times the amount of water for the third time, decoct After 1 hour, the water extracts were combined, concentrated under reduced pressure to form a thick paste with a relative density of 1.10 measured at 60°C, spray-dried, pulverized, and sieved to obtain 22.4Kg fine powder;

[0026] (2) Add appropriate amount of starch and hydroxypropyl cellulose to the fine powder obtained in step 1, mix well, add appropriate amount of 80% ethanol to make granules, press into tablets, each tablet is 350mg, and a total of 64176 tablets are obtained.

[0027] Dosage: 5 tablets each ti...

Embodiment 2

[0028] Example 2 A kind of traditional Chinese medicine composition capsule

[0029] Composition of API: (unit: 100g)

[0030] Dandelion 45, Gualoupi 45, Tu Fritillaria 30, Yuan Hu 13.5.

[0031] The preparation method is as follows:

[0032] (1) Add water to decoct the raw material three times, add 10 times the amount of water for the first time, decoct for 3 hours; add 7 times the amount of water for the second time, decoct for 2 hours; add 6 times the amount of water for the third time, decoct After 1 hour, the water extracts were combined, concentrated under reduced pressure to form a thick paste with a relative density of 1.06 measured at 60°C, spray-dried, pulverized, and sieved to obtain 3.27Kg fine powder;

[0033] (2) Add appropriate amount of calcium phosphate and calcium hydrogen phosphate to the fine powder obtained in step 1, mix evenly, add appropriate amount of 80% ethanol to make granules, dry, granulate, put into capsules, each 350mg, and a total of 9524 g...

Embodiment 3

[0035] Example 3 A kind of traditional Chinese medicine composition soft capsule

[0036] Raw material composition: (unit: Kg)

[0037] 50 parts of Dandelion, 50 parts of Gualou skin, 35 parts of Tu Fritillaria, and 15 parts of Yuanhu.

[0038] The preparation method is as follows:

[0039] (1) Add water to decoct the raw material three times, add 9 times the amount of water for the first time, decoct for 2 hours; add 8 times the amount of water for the second time, decoct for 1.5 hours; add 7 times the amount of water for the third time, decoct After 1.5 hours, the filtrates were combined, filtered, and the filtrate was concentrated under reduced pressure into a thick paste with a relative density of 1.05 measured at 57°C, spray-dried, pulverized, and sieved to obtain 29.4Kg fine powder;

[0040] (2) Add the fine powder obtained in step 1 to beeswax, hydrogenated palm oil, and soybean lecithin, stir well, mix evenly, let stand, and vacuumize until the air bubbles in the l...

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Abstract

The invention provides a traditional Chinese medicinal composition. The composition is prepared from the following raw materials, by weight, 40-50 parts of Herba Taraxaci, 40-50 parts of snakegourd peel, 25-35 parts of Rhizoma Bolbostematis and 10-15 parts of corydalis tuber, and is preferably prepared from 45 parts of Herba Taraxaci, 45 parts of snakegourd peel, 30 parts of Rhizoma Bolbostematis and 13.5 parts of corydalis tuber. The invention also provides a preparation method of the traditional Chinese medicinal composition, and a use of the composition in the treatment of mastitis and breast distending pain. The traditional Chinese medicinal composition has the advantages of simple composition, definite therapeutic effect on mastitis and breast distending pain, good safety and simple preparation method.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating mastitis and breast tenderness, a preparation method and application thereof. Background technique [0002] Mastitis is a common acute suppurative disease in postpartum lactating women. It is more common in primiparous women and occurs in 3 to 4 weeks postpartum, so it is also called "postpartum mastitis"; of course, it can also occur in other periods . Traditional Chinese medicine believes that this disease is mostly caused by overeating delicious food, accumulated heat in the stomach meridian; or worry and anger, stagnant fire in the liver meridian; or cracked nipple skin, exogenous fire poison invades the breast, etc., resulting in different veins in the breast and poor milk discharge. The stagnant heat, fire toxin and accumulated milk coagulate each other, resulting in carbuncle. The clinical manifestations of breas...

Claims

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Application Information

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IPC IPC(8): A61K36/66A61K9/20A61K9/48A61K9/16A61P15/14A61P29/00
Inventor 胡小虎王贝赵宗平
Owner XIAN CHIHO PHARMA