Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of zinc ion sensor molecule and its preparation and application

A zinc ion and sensor technology, applied in the field of cation detection, can solve problems such as complex electrical instruments, tedious sample preparation process, etc.

Inactive Publication Date: 2017-12-29
NORTHWEST NORMAL UNIVERSITY
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these methods require complex electrical instruments and tedious sample preparation processes
However, there are no reports on chemical sensors for the detection of zinc ions.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of zinc ion sensor molecule and its preparation and application
  • A kind of zinc ion sensor molecule and its preparation and application
  • A kind of zinc ion sensor molecule and its preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] The structure and synthesis of the sensor molecule of the present invention, the fluorescence recognition method for zinc ions, the preparation and application of the detection test paper will be described in detail below through specific examples.

[0041] 1. Synthesis and characterization of sensor molecules

[0042] In a 250mL round-bottomed flask, add 0.7500g (5mmol) of hydroxyisophthalaldehyde, 0.5995g (5.5mmol) of 2-hydrazinopyridine, 5mL (0.05mmol) of glacial acetic acid for catalyst, 30mL of ethanol solvent, and stir at reflux at 80°C After 6 hours, a brown-yellow precipitate precipitated out, and the crude product was recrystallized from ethanol to obtain a dark-yellow product, which is the sensor molecule Y, with a yield of 86.2% (m.p. > 300°C). Its structure is characterized as follows:

[0043] 1 H NMR (DMSO– d 6 , 400 MHz) δ: 11.01(s, 1H, O-H); δ: 10.80 (s, 1H, N–H);δ: 10.72 (s, 1H, N–H); δ: 8.31 (s, 1H, CH =N). IR (KBr) ν: 1622 cm -1 (-HC=N-),3422 c...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
volume ratioaaaaaaaaaa
Login to View More

Abstract

The invention discloses a zinc ion sensor molecule, which belongs to the field of cation detection. The sensor molecules of the present invention contain hydrazone and imine functional groups, based on their strong complexation to metal cations, which hinder excited state intramolecular proton transfer (ESIPT) and -HC=N-isomerization processes, resulting in the opening of fluorescence and Identify and detect Zn2+. Experiments show that the sensor molecule in the HEPES buffer system of DMSO / H2O, only the addition of Zn2+ makes the system emit a significant yellow-green fluorescence under ultraviolet light, and in the corresponding fluorescence spectrum, only the addition of Zn2+ makes the buffer system of the sensor molecule The maximum fluorescence emission peak appears at 524nm. Therefore, the sensor molecule can be used for the rapid fluorescence detection of Zn2+, and its minimum detection limit can reach 1.39×10‑8M, and the recognition of Zn2+ by other cations has no serious interference.

Description

technical field [0001] The invention belongs to the field of cation detection, and relates to the preparation of a zinc ion sensor molecule; the invention also relates to the application of the sensor molecule in highly selective fluorescent recognition of zinc ions. Background technique [0002] Zinc ions play a very important role in catalysis and structure, can contain biological enzymes and bind DNA proteins. However, an imbalance in the level of zinc ions in the body may lead to some serious neurological diseases, such as Alzheimer's disease, cerebral ischemia and epilepsy, developmental defects or disabilities. Therefore, people pay more and more attention and are committed to the development and research of efficient and highly selective detection of Zn 2+ methods, such as inductively coupled plasma atomic emission spectrometry, atomic absorption spectrometry, electrochemical methods, etc. However, most of these methods require complex electrical instruments and ted...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07D213/77G01N21/64
Inventor 林奇蔡毅李乔姚虹张有明魏太保
Owner NORTHWEST NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com