Adsorbent capable of reducing in vivo urotoxin

A technology for adsorbents and urea toxins, applied in the direction of anti-drugs, urinary system diseases, carbon active ingredients, etc., can solve the problems of interfering with the normal function of the gastrointestinal tract, limited effect, poor adsorption of urea toxin precursors, etc., and achieve high adsorption force, reduce the incidence, reduce the effect of accumulation
CN104666342AInactive Publication Date: 2015-06-03JINGYUN BIOLOGICAL TECH SHANGHAI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JINGYUN BIOLOGICAL TECH SHANGHAI
Publication Date
2015-06-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an adsorbent capable of reducing in vivo urotoxin. The adsorbent comprises a polyacrylonitrile active carbon fiber with the characteristics that (1) the mean diameter is 5-30 microns; (2) the BET specific surface area is greater than 390m<2> / g; and (3) the total acidic group is greater than 1.2meq / g or the total basic group is greater than 1meq / g. The adsorbent has relatively high adsorption capacity on an urotoxin precursor, but has relatively low adsorption capacity on normal ferment in intestinal tracts. Therefore, the urotoxin adsorbent disclosed by the invention is capable of effectively relieving deterioration of the renal function, and is used as a therapeutic agent or a preventive for kidney diseases.
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Description

technical field

[0001] The present invention relates to an oral substance for treating or preventing kidney diseases, in particular to an adsorbent capable of reducing uremic toxins in the body, which is used for reducing uremic toxins in individuals and slowing down the deterioration of renal function. Background technique

[0002] The metabolic wastes excreted by the kidneys are commonly called urea toxins, and the concentration of urea toxins in serum can be used as an indicator of renal function. A uremic toxin: indoxyl sulfate (indoxyl sulfate) is considered to be one of the main causes of exacerbation of chronic kidney disease. The production process of indoxyl sulfate is that the bacteria in the intestine metabolize the tryptophan (Tryptophan) ingested from food into indole (Indole), and indole is metabolized into indoxyl sulfate in the liver, and then excreted through the kidneys. When renal function declines, indoxyl sulfate and other urea toxins, such as creatinin...

Claims

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