Anti-tuberculous traditional Chinese medicine fritillary and burdock fruit tuberculosis-eliminating extractive and application

Abstract

The invention relates to an anti-tuberculous traditional Chinese medicine fritillary and burdock fruit tuberculosis-eliminating extractive and application and belongs to the field of traditional Chinese medicine treatment preparations. Alcohol water, water and / or alcohol are adopted to extract three extractives, adopted raw medicinal materials include, by weight, 3-5 parts of burdock fruits, 5-10 parts of common bletilla pseudobulb, 3-5 parts of fritillary fruits, 3-5 parts of platycodon grandiflorum, 3-10 parts of sticky rice and 3-5 parts of houttuynia cordata and are weighed in proportion, ethyl alcohol and / or water are / is added into the raw medicinal materials, heating is performed for reflux extraction after soaking, filtration is performed to obtain an extracting solution, pressure reduction is performed to recover a solvent, the solvent is concentrated to form thick paste, pressure-reduction drying is performed to form dry paste, and the dry paste is smashed and screened to obtain the extractive. The fritillary and burdock fruit tuberculosis-eliminating extractive serves as a traditional Chinese medicine treatment preparation and enables the weight of a mouse to be inordinately increased than the weight before the mouse is treated, and the weight is more than the weight increased by means of existing medicine powder combinations. Bacterial quantity of the spleen tissues can be remarkably decreased, the lung lesions are inordinately relieved, and a normal lung structure can be seen. The fritillary and burdock fruit tuberculosis-eliminating extractive is better than existing medicine powder in overall treatment effect and can be used for preparation of medicines for treating tuberculosis of patients.

Description

technical field [0001] The invention relates to an anti-tuberculosis traditional Chinese medicine Niubei Xiaonuo extract and its preparation and application, in particular to three Chinese medicine Niubei Xiaonuo extracts for antibacterial, especially anti-tuberculosis, and their preparation and application, belonging to the field of traditional Chinese medicine treatment preparations. Background technique [0002] Tuberculosis (TB) is a serious respiratory infectious disease caused by Mycobacterium tuberculosis (MTB). Although the number of tuberculosis patients worldwide has decreased, the number of patients with multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) continues to increase. According to the 2013 WHO Global Tuberculosis Report: In 2012, there were 8.7 million new tuberculosis patients worldwide and 1.3 million tuberculosis patients died of it. MDR-TB cases rose in 27 high MDR-TB burden countries, with 450 000 MDR-TB a...

AI Technical Summary

Problems solved by technology

[0008] The Chinese invention patent with the patent number 200710048778.X has the following disadvantages: first, because the invention patent is only to clean each Chinese herbal medicine, air-dry, pulverize, then mix and package, resulting in large dosage and poor patient compliance ; secondly, some active ingredients are not easy to release in the gastrointestinal tract; thirdly, although the Chinese medicinal materials have been cleaned, they have not been aseptically processed, and the bacteria contained in them do not rule out the possibility of infection in tuberculosis patients with low immunity

[0011] The inventors have found that it has a better effect on improving the liver lesions caused by tuberculosis, but the improvement effects on lung lesions and emaciation (weight loss) caused by tuberculosis are general or even ineffective.

Images