Coccidian vaccine immunopotentiation suspending agent and preparation method thereof

Abstract

The invention discloses a coccidian vaccine immunopotentiation suspending agent which comprises the following raw materials in parts by mass: 0.05-3 parts of Carbomer934P, 0.15-4 parts of hydroxypropyl methyl cellulose, 1-55 parts of astragalus polysaccharide, 0.5-30 parts of chitosan, and 0.9-35 parts of poloxamer. A preparation method of the coccidian vaccine immunopotentiation suspending agent comprises the following steps: respectively taking Carbomer, 4 parts of hydroxypropyl methyl cellulose, astragalus polysaccharide, chitosan and poloxamer in parts by mass, stirring and uniformly mixing at normal temperature, and storing at normal temperature. A using method of the coccidian vaccine immunopotentiation suspending agent comprises the following steps: at first, feeding 1 part of the coccidian vaccine immunopotentiation suspending agent into 25 parts of clear water, stirring for 5-10 minutes, diluting into a suspending solution, then adding each part of live coccidian vaccine into 6 ml of the suspending solution, stirring and uniformly mixing, and drinking the mixture freely by chicken. The suspending agent is lasting in suspending effect, and efficient in immune effect, can shorten the immunifacient stage, and achieves the effects that water is continuously fed before immunization, the immunizing dose is uniform, and the immunifacient stage is short.

Description

technical field [0001] The invention belongs to animal vaccine suspending agent, in particular to a chicken coccidiosis live oocyst vaccine immune synergistic suspending agent used for drinking water immunization. Background technique [0002] Chicken coccidiosis (coccidiosis) is a protozoan disease caused by one or more of the nine species of Eimeria coccidiosis parasitizing in intestinal epithelial cells, mainly caused by diarrhea, intestinal damage or bloody stool. features. It is a common and serious disease. Chicken coccidiosis occurs in almost all chicken farms. Intensive chicken farms are the most important places where coccidiosis breaks out. The incidence of coccidiosis is 50% to 70%, and the mortality rate is 20% to 30%. In severe cases, it can be as high as 80%. Among all chicken diseases, the incidence of coccidiosis is the highest, accounting for about 20%. Even the diseased chickens that have tolerated it can not recover to the level before the infection, a...

AI Technical Summary

Problems solved by technology

The technology of coccidia vaccine suspending agent has been documented, for example, Chinese patent 200510036004.6 discloses a kind of coccidia vaccine suspending agent and its processing technology to be prepared from following raw material and technology: its component content (by suspending agent 100% by weight) carboxymethyl cellulose 5%-20%, air-dried powder 0.5%-3%, and the rest are oligosaccharides, which can suspend coccidia oocysts in water for 6 hours without sedimentation, but have no synergistic effect and the effect of shortening the period of immune production

Images